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2020

Evaluating the Effects of Canagliflozin on Cardiovascular and Renal Events in Patients With Type 2 Diabetes Mellitus and Chronic Kidney Disease According to Baseline HbA1c, Including Those With HbA1c <7%: Results From the CREDENCE Trial

Cannon, C. P., Perkovic, V., Agarwal, R., Baldassarre, J., Bakris, G., Charytan, D. M., de Zeeuw, D., Edwards, R., Greene, T., Heerspink, H. J. L., Jardine, M. J., Levin, A., Li, J. W., Neal, B., Pollock, C., Wheeler, D. C., Zhang, H., Zinman, B. & Mahaffey, K. W., Feb 4 2020, In : Circulation. 141, 5, p. 407-410 4 p.

Research output: Contribution to journalLetter

Open Access

Extravascular Lung Water Assessment by Ultrasound to Guide Dry Weight Changes: Ready for Prime Time?

Agarwal, R., Toto, R. D. & Weir, M. R., Jan 2020, In : American Journal of Kidney Diseases. 75, 1, p. 1-3 3 p.

Research output: Contribution to journalEditorial

Open Access
2019
2 Citations (Scopus)

Ambulatory Blood Pressure Reduction With SGLT-2 Inhibitors: Dose-Response Meta-analysis and Comparative Evaluation With Low-Dose Hydrochlorothiazide

Georgianos, P. I. & Agarwal, R., Apr 1 2019, In : Diabetes care. 42, 4, p. 693-700 8 p.

Research output: Contribution to journalReview article

Sodium-Glucose Transport Proteins
Hydrochlorothiazide
Meta-Analysis
Blood Pressure
Randomized Controlled Trials
Angiotensin Receptor Antagonists
Angiotensin-Converting Enzyme Inhibitors
Chronic Kidney Failure
Longitudinal Studies
Cohort Studies

Assessment and management of hypertension among patients on peritoneal dialysis

Vaios, V., Georgianos, P. I., Liakopoulos, V. & Agarwal, R., Feb 7 2019, In : Clinical Journal of the American Society of Nephrology. 14, 2, p. 297-305 9 p.

Research output: Contribution to journalArticle

Peritoneal Dialysis
Hypertension
Renal Dialysis
Dietary Sodium
Renal Replacement Therapy
6 Citations (Scopus)

Canagliflozin and Cardiovascular and Renal Outcomes in Type 2 Diabetes Mellitus and Chronic Kidney Disease in Primary and Secondary Cardiovascular Prevention Groups

Mahaffey, K. W., Jardine, M. J., Bompoint, S., Cannon, C. P., Neal, B., Heerspink, H. J. L., Charytan, D. M., Edwards, R., Agarwal, R., Bakris, G., Bull, S., Capuano, G., de Zeeuw, D., Greene, T., Levin, A., Pollock, C., Sun, T., Wheeler, D. C., Yavin, Y., Zhang, H. & 4 others, Zinman, B., Rosenthal, N., Brenner, B. M. & Perkovic, V., Aug 27 2019, In : Circulation. 140, 9, p. 739-750 12 p.

Research output: Contribution to journalArticle

Open Access
Secondary Prevention
Chronic Renal Insufficiency
Type 2 Diabetes Mellitus
Kidney
Primary Prevention
259 Citations (Scopus)

Canagliflozin and renal outcomes in type 2 diabetes and nephropathy

for the CREDENCE Trial Investigators, Jun 13 2019, In : New England Journal of Medicine. 380, 24, p. 2295-2306 12 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Kidney
Confidence Intervals
Chronic Kidney Failure
Placebos
8 Citations (Scopus)

Cardiovascular outcome trials in patients with chronic kidney disease: Challenges associated with selection of patients and endpoints

Rossignol, P., Agarwal, R., Canaud, B., Charney, A., Chatellier, G., Craig, J. C., Cushman, W. C., Gansevoort, R. T., Fellström, B., Garza, D., Guzman, N., Holtkamp, F. A., London, G. M., Massy, Z. A., Mebazaa, A., Mol, P. G. M., Pfeffer, M. A., Rosenberg, Y., Ruilope, L. M., Seltzer, J. & 15 others, Shah, A. M., Shah, S., Singh, B., Stefánsson, B. V., Stockbridge, N., Stough, W. G., Thygesen, K., Walsh, M., Wanner, C., Warnock, D. G., Wilcox, C. S., Wittes, J., Pitt, B., Thompson, A. & Zannad, F., Mar 14 2019, In : European Heart Journal. 40, 11, p. 880-886 7 p.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Patient Selection
Cardiovascular Diseases
Kidney
Chronic Kidney Failure

Caring for individuals with hypertension in CKD, especially those with low education

Agarwal, R., Oct 1 2019, In : Kidney international. 96, 4, p. 820-822 3 p.

Research output: Contribution to journalComment/debate

Hypertension
Education
Spironolactone
Albuminuria
Potassium
3 Citations (Scopus)
Open Access
Clinical Pharmacology
Antihypertensive Agents
Hypertension
Sodium Chloride Symporter Inhibitors
Adrenergic Antagonists
1 Citation (Scopus)

Design and baseline characteristics of the finerenone in reducing cardiovascular mortality and morbidity in diabetic kidney disease trial

Ruilope, L. M., Agarwal, R., Anker, S. D., Bakris, G. L., Filippatos, G., Nowack, C., Kolkhof, P., Joseph, A., Mentenich, N. & Pitt, B., Jan 1 2019, (Accepted/In press) In : American Journal of Nephrology.

Research output: Contribution to journalArticle

Open Access
Diabetic Nephropathies
Morbidity
Chronic Renal Insufficiency
Mortality
Type 2 Diabetes Mellitus
1 Citation (Scopus)

Design and baseline characteristics of the finerenone in reducing kidney failure and disease progression in diabetic kidney disease trial

Bakris, G. L., Agarwal, R., Anker, S. D., Pitt, B., Ruilope, L. M., Nowack, C., Kolkhof, P., Ferreira, A. C., Schloemer, P. & Filippatos, G., Jan 1 2019, (Accepted/In press) In : American Journal of Nephrology.

Research output: Contribution to journalArticle

Open Access
Kidney Diseases
Diabetic Nephropathies
Renal Insufficiency
Disease Progression
Chronic Renal Insufficiency
1 Citation (Scopus)
Glomerular Filtration Rate
Chronic Renal Insufficiency
Albuminuria
Quality of Life
Sarcopenia

Hypertension in chronic kidney disease: Nephrology Dialysis Transplantation notable 2017 advances

Georgianos, P. I. & Agarwal, R., Jan 1 2019, In : Nephrology Dialysis Transplantation. 34, 1, p. 1-4 4 p.

Research output: Contribution to journalReview article

Open Access
Nephrology
Chronic Renal Insufficiency
Dialysis
Transplantation
Hypertension

Intravenous iron and maintenance hemodialysis

Agarwal, R., Jun 13 2019, In : New England Journal of Medicine. 380, 24, p. E46

Research output: Contribution to journalLetter

Renal Dialysis
Iron
Maintenance
3 Citations (Scopus)

KDOQI US Commentary on the 2017 ACC/AHA Hypertension Guideline

Kramer, H. J., Townsend, R. R., Griffin, K., Flynn, J. T., Weiner, D. E., Rocco, M. V., Choi, M. J., Weir, M. R., Chang, T. I., Agarwal, R. & Beddhu, S., Apr 1 2019, In : American Journal of Kidney Diseases. 73, 4, p. 437-458 22 p.

Research output: Contribution to journalArticle

American Heart Association
Kidney Diseases
Cardiology
Guidelines
Hypertension
5 Citations (Scopus)

Patiromer versus placebo to enable spironolactone use in patients with resistant hypertension and chronic kidney disease (AMBER): a phase 2, randomised, double-blind, placebo-controlled trial

Agarwal, R., Rossignol, P., Romero, A., Garza, D., Mayo, M. R., Warren, S., Ma, J., White, W. B. & Williams, B., Oct 26 2019, In : The Lancet. 394, 10208, p. 1540-1550 11 p.

Research output: Contribution to journalArticle

Spironolactone
Chronic Renal Insufficiency
Placebos
Hypertension
Hyperkalemia

Rehospitalization Rates in Hypertensive Emergency

Agarwal, R., Jan 1 2019, In : Hypertension (Dallas, Tex. : 1979). 73, 1, p. 49-51 3 p.

Research output: Contribution to journalEditorial

Emergencies

Review: Automated office BP measures are similar to awake ambulatory BP and lower than other office BP measures

Georgianos, P. I. & Agarwal, R., Jun 18 2019, In : Annals of internal medicine. 170, 12, p. JC69

Research output: Contribution to journalComment/debate

Systolic and diastolic hypertension among patients on hemodialysis: Musings on volume overload, arterial stiffness, and erythropoietin

Georgianos, P. I. & Agarwal, R., Jan 1 2019, (Accepted/In press) In : Seminars in Dialysis.

Research output: Contribution to journalReview article

Vascular Stiffness
Erythropoietin
Renal Dialysis
Hypertension
Antihypertensive Agents

Systolic Blood Pressure Intervention Trial and Statins, a Story of Statistical Interaction

Tu, W. & Agarwal, R., Jan 1 2019, In : American Journal of Nephrology. p. 294-296 3 p.

Research output: Contribution to journalReview article

Open Access
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Blood Pressure
2018
2 Citations (Scopus)

Big data in nephrology-a time to rethink

Agarwal, R. & Sinha, A., Jan 1 2018, In : Nephrology Dialysis Transplantation. 33, 1, p. 1-3 3 p.

Research output: Contribution to journalReview article

Nephrology
2 Citations (Scopus)

Blood pressure control in conventional hemodialysis

Georgianos, P. I. & Agarwal, R., Jan 1 2018, (Accepted/In press) In : Seminars in Dialysis.

Research output: Contribution to journalArticle

Renal Dialysis
Blood Pressure
Sodium
Renin-Angiotensin System
Antihypertensive Agents
3 Citations (Scopus)

Creatinine Bump Following Antihypertensive Therapy

Bakris, G. L. & Agarwal, R., Dec 1 2018, In : Hypertension (Dallas, Tex. : 1979). 72, 6, p. 1274-1276 3 p.

Research output: Contribution to journalEditorial

Blood Pressure Determination
Type 2 Diabetes Mellitus
Antihypertensive Agents
Creatinine
Blood Pressure

Feeding during dialysis - Risks and uncertainties

Agarwal, R. & Georgianos, P., Jun 1 2018, In : Nephrology Dialysis Transplantation. 33, 6, p. 917-922 6 p.

Research output: Contribution to journalReview article

Uncertainty
Dialysis
Eating
Meals
Postprandial Period

Kidney parenchymal hypertension

Andersen, M. J. & Agarwal, R., Mar 30 2018, Nephrology Secrets: Fourth Edition. Elsevier Inc., p. 438-443 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Hypertension
Kidney
4 Citations (Scopus)

Mechanisms and mediators of hypertension induced by erythropoietin and related molecules

Agarwal, R., Oct 1 2018, In : Nephrology Dialysis Transplantation. 33, 10, p. 1690-1698 9 p.

Research output: Contribution to journalReview article

Erythropoietin
Hypertension
Hemoglobins
Chronic Renal Insufficiency
Antihypertensive Agents

Meet the twins: Intradialytic and interdialytic hypertension

Georgianos, P. I. & Agarwal, R., Nov 1 2018, In : American Journal of Nephrology. 48, 4, p. 292-294 3 p.

Research output: Contribution to journalReview article

Hypertension
Chronic Renal Insufficiency
Ambulatory Blood Pressure Monitoring
Blood Pressure
Reading
Hypertension

Nonpharmacologic treatment of hypertension

Andersen, M. J. & Agarwal, R., Mar 30 2018, Nephrology Secrets: Fourth Edition. Elsevier Inc., p. 483-486 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Hypertension
6 Citations (Scopus)

Patiromer to Enable Spironolactone Use in the Treatment of Patients with Resistant Hypertension and Chronic Kidney Disease: Rationale and Design of the AMBER Study

Agarwal, R., Rossignol, P., Garza, D., Mayo, M. R., Warren, S., Arthur, S., Romero, A., White, W. B. & Williams, B., Jan 1 2018, (Accepted/In press) In : American Journal of Nephrology. p. 172-180 9 p.

Research output: Contribution to journalArticle

Spironolactone
Chronic Renal Insufficiency
Hypertension
Potassium
Hyperkalemia
2017
6 Citations (Scopus)

A Comparison of the Safety and Efficacy of HX575 (Epoetin Alfa Proposed Biosimilar) with Epoetin Alfa in Patients with End-Stage Renal Disease

Weir, M. R., Pergola, P. E., Agarwal, R., Fink, J. C., Kopyt, N. P., Singh, A. K., Kumar, J., Schmitt, S., Schaffar, G., Rudy, A., McKay, J. P. & Kanceva, R., Oct 30 2017, (Accepted/In press) In : American Journal of Nephrology. p. 364-370 7 p.

Research output: Contribution to journalArticle

Epoetin Alfa
Biosimilar Pharmaceuticals
Chronic Kidney Failure
Safety
Hemoglobins
4 Citations (Scopus)

Albuminuria and masked uncontrolled hypertension in chronic kidney disease

Agarwal, R., Dec 1 2017, In : Nephrology Dialysis Transplantation. 32, 12, p. 2058-2065 8 p.

Research output: Contribution to journalArticle

Masked Hypertension
Albuminuria
Chronic Renal Insufficiency
Pulse Wave Analysis
Cardiovascular Diseases
1 Citation (Scopus)

Altered circadian hemodynamic and renal function in cirrhosis

Liangpunsakul, S. & Agarwal, R., Feb 1 2017, In : Nephrology Dialysis Transplantation. 32, 2, p. 333-342 10 p.

Research output: Contribution to journalArticle

Fibrosis
Hemodynamics
Blood Pressure
Kidney
Endotoxemia
3 Citations (Scopus)
Vascular Stiffness
Chronic Renal Insufficiency
Pulse Wave Analysis
Longitudinal Studies
Blood Pressure
14 Citations (Scopus)

Blood pressure and mortality in long-term hemodialysis-time to move forward

Georgianos, P. I. & Agarwal, R., Jan 1 2017, In : American Journal of Hypertension. 30, 3, p. 211-222 12 p.

Research output: Contribution to journalReview article

Renal Dialysis
Blood Pressure
Mortality
Dialysis
Hypertension
4 Citations (Scopus)

Blood pressure in hemodialysis: Targets?

Georgianos, P. I. & Agarwal, R., Nov 1 2017, In : Current Opinion in Nephrology and Hypertension. 26, 6, p. 523-529 7 p.

Research output: Contribution to journalReview article

Renal Dialysis
Blood Pressure
Dialysis
Hypertension
Mortality

Blood pressure is blood pressure is blood pressure: Or is it?

Agarwal, R., 2017, (Accepted/In press) In : Journal of Clinical Hypertension.

Research output: Contribution to journalArticle

3 Citations (Scopus)
Masked Hypertension
Chronic Renal Insufficiency
Exercise
Blood Pressure
Hypertension
8 Citations (Scopus)

Diagnosing and managing sleep apnea in patients with chronic cerebrovascular disease: a randomized trial of a home-based strategy

Bravata, D., McClain, V., Austin, C., Ferguson, J., Burrus, N., Miech, E., Matthias, M., Chumbler, N., Ofner, S., Foresman, B., Sico, J., Vaz Fragoso, C. A., Williams, L., Agarwal, R., Concato, J. & Klar Yaggi, H., Apr 6 2017, (Accepted/In press) In : Sleep and Breathing. p. 1-13 13 p.

Research output: Contribution to journalArticle

Cerebrovascular Disorders
Sleep Apnea Syndromes
Chronic Disease
Obstructive Sleep Apnea
Continuous Positive Airway Pressure
90 Citations (Scopus)
Methylprednisolone
Immunoglobulin A
Randomized Controlled Trials
Steroids
Glomerular Filtration Rate
5 Citations (Scopus)

Endothelin A receptor antagonists in diabetic kidney disease

Georgianos, P. I. & Agarwal, R., Sep 1 2017, In : Current Opinion in Nephrology and Hypertension. 26, 5, p. 338-344 7 p.

Research output: Contribution to journalReview article

Diabetic Nephropathies
Proteinuria
Chronic Kidney Failure
Endothelins
Renin-Angiotensin System
1 Citation (Scopus)
Glomerular Filtration Rate
11 Citations (Scopus)

Hypertension in dialysis patients: a consensus document by the European Renal and Cardiovascular Medicine (EURECA-m) working group of the European Renal Association – European Dialysis and Transplant Association (ERA-EDTA) and the Hypertension and the Kidney working group of the European Society of Hypertension (ESH)

Sarafidis, P. A., Persu, A., Agarwal, R., Burnier, M., de Leeuw, P., Ferro, C., Halimi, J. M., Heine, G., Jadoul, M., Jarraya, F., Kanbay, M., Mallamaci, F., Mark, P. B., Ortiz, A., Parati, G., Pontremoli, R., Rossignol, P., Ruilope, L., van der Niepen, P., Vanholder, R. & 5 others, Verharr, M. C., Wiecek, A., Wuerzner, G., London, G. M. & Zoccali, C., Feb 2 2017, (Accepted/In press) In : Journal of Hypertension.

Research output: Contribution to journalArticle

Dialysis
Medicine
Hypertension
Transplants
Kidney
35 Citations (Scopus)

Hypertension in dialysis patients: A consensus document by the European Renal and Cardiovascular Medicine (EURECA-m) working group of the European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) and the Hypertension and the Kidney working group of the European Society of Hypertension (ESH)∗

Sarafidis, P. A., Persu, A., Agarwal, R., Burnier, M., De Leeuw, P., Ferro, C. J., Halimi, J. M., Heine, G. H., Jadoul, M., Jarraya, F., Kanbay, M., Mallamaci, F., Mark, P. B., Ortiz, A., Parati, G., Pontremoli, R., Rossignol, P., Ruilope, L., Van Der Niepen, P., Vanholder, R. & 5 others, Verhaar, M. C., Wiecek, A., Wuerzner, G., London, G. M. & Zoccali, C., Apr 1 2017, In : Nephrology Dialysis Transplantation. 32, 4, p. 620-640 21 p.

Research output: Contribution to journalReview article

Dialysis
Medicine
Hypertension
Transplants
Kidney
57 Citations (Scopus)
Blood Pressure
Left Ventricular Hypertrophy
Research
Research Design
5 Citations (Scopus)

Iron deficiency anemia in chronic kidney disease: Uncertainties and cautions

Agarwal, R., Jul 1 2017, In : Hemodialysis International. 21, p. S78-S82

Research output: Contribution to journalReview article

Iron-Deficiency Anemias
Chronic Renal Insufficiency
Uncertainty
Iron
Intravenous Administration

Modification of Potassium-Mortality Relationship by Ethnicity and Race: Solving the Puzzle

Agarwal, R., Jun 1 2017, In : American Journal of Nephrology. 45, 6, p. 552-554 3 p.

Research output: Contribution to journalReview article

Potassium
Mortality
15 Citations (Scopus)

Revisiting RAAS blockade in CKD with newer potassium-binding drugs

Georgianos, P. I. & Agarwal, R., Jan 1 2017, (Accepted/In press) In : Kidney International.

Research output: Contribution to journalArticle

Renin-Angiotensin System
Chronic Renal Insufficiency
Potassium
Hyperkalemia
Pharmaceutical Preparations
8 Citations (Scopus)

Setting the dry weight and its cardiovascular implications

Sinha, A. & Agarwal, R., 2017, (Accepted/In press) In : Seminars in Dialysis.

Research output: Contribution to journalArticle

Weights and Measures
Dialysis
Left Ventricular Hypertrophy
Renal Dialysis
Standard of Care