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  • Larry Cripe

Aberrant GSK3β nuclear localization promotes AML growth and drug resistance

Ignatz-Hoover, J. J., Wang, V., Mackowski, N. M., Roe, A. J., Ghansah, I. K., Ueda, M., Lazarus, H. M., Lima, M. D., Paietta, E., Fernandez, H., Cripe, L., Tallman, M. & Wald, D. N., Nov 13 2018, In : Blood Advances. 2, 21, p. 2890-2903 14 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Allogeneic hematopoietic cell transplantation compared to chemotherapy consolidation in older acute myeloid leukemia (AML) patients 60–75 years in first complete remission (CR1): an alliance (A151509), SWOG, ECOG-ACRIN, and CIBMTR study

Ustun, C., Le-Rademacher, J., Wang, H. L., Othus, M., Sun, Z., Major, B., Zhang, M. J., Storrick, E., Lafky, J. M., Chow, S., Mrózek, K., Attar, E. C., Nand, S., Bloomfield, C. D., Cripe, L. D., Tallman, M. S., Appelbaum, F., Larson, R. A., Marcucci, G., Roboz, G. J. & 12 others, Uy, G. L., Stone, R. M., Jatoi, A., Shea, T. C., de Lima, M., Foran, J. M., Sandmaier, B. M., Litzow, M. R., Erba, H. P., Hurria, A., Weisdorf, D. J. & Artz, A. S., Nov 1 2019, In : Leukemia. 33, 11, p. 2599-2609 11 p.

Research output: Contribution to journalArticle

10 Scopus citations
1 Scopus citations

A noncanonical Flt3ITD/NF-κB signaling pathway represses DAPK1 in acute myeloid leukemia

Shanmugam, R., Gade, P., Wilson-Weekes, A., Sayar, H., Suvannasankha, A., Goswami, C., Li, L., Gupta, S., Cardoso, A. A., Al Baghdadi, T., Sargent, K. J., Cripe, L. D., Kalvakolanu, D. V. & Boswell, H. S., Jan 15 2012, In : Clinical Cancer Research. 18, 2, p. 360-369 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

A phase 1b/2 study of vosaroxin in combination with cytarabine in patients with relapsed or refractory acute myeloid leukemia

Lancet, J. E., Roboz, G. J., Cripe, L. D., Michelson, G. C., Fox, J. A., Leavitt, R. D., Chen, T., Hawtin, R., Craig, A. R., Ravandi, F., Maris, M. B., Stuart, R. K. & Karp, J. E., Jan 1 2015, In : Haematologica. 100, 2, p. 231-237 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

A phase Ib study of vosaroxin, an anticancer quinolone derivative, in patients with relapsed or refractory acute leukemia

Lancet, J. E., Ravandi, F., Ricklis, R. M., Cripe, L. D., Kantarjian, H. M., Giles, F. J., List, A. F., Chen, T., Allen, R. S., Fox, J. A., Michelson, G. C. & Karp, J. E., Dec 2011, In : Leukemia. 25, 12, p. 1808-1814 7 p.

Research output: Contribution to journalArticle

37 Scopus citations

Cell signaling-based classifier predicts response to induction therapy in elderly patients with acute myeloid leukemia

Cesano, A., Willman, C. L., Kopecky, K. J., Gayko, U., Putta, S., Louie, B., Westfall, M., Purvis, N., Spellmeyer, D. C., Marimpietri, C., Cohen, A. C., Hackett, J., Shi, J., Walker, M. G., Sun, Z., Paietta, E., Tallman, M. S., Cripe, L. D., Atwater, S., Appelbaum, F. R. & 1 others, Radich, J. P., Apr 17 2015, In : PloS one. 10, 4, e0118485.

Research output: Contribution to journalArticle

4 Scopus citations

Combination of sorafenib, vorinostat and bortezomib for the treatment of poor-risk AML: report of two consecutive clinical trials

Sayar, S., Cripe, L. D., Saliba, A. N., Abu Zaid, M., Konig, H. & Boswell, H. S., Feb 2019, In : Leukemia Research. 77, p. 30-33 4 p.

Research output: Contribution to journalLetter

3 Scopus citations

Consecutive epigenetically-active agent combinations act in ID1-RUNX3-TET2 and HOXA pathways for Flt3ITD+ve AML

Sayar, H., Liu, Y., Gao, R., Zaid, M. A., Cripe, L. D., Weisenbach, J., Sargent, K. J., Nassiri, M., Li, L., Konig, H., Suvannasankha, A., Pan, F., Shanmugam, R., Goswami, C., Kapur, R., Xu, M. & Scott Boswell, H., 2018, In : Oncotarget. 9, 5, p. 5703-5715 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

Cyclophosphamide/fludarabine nonmyeloablative allotransplant for acute myeloid leukemia

Khawaja, M. R., Perkins, S. M., Schwartz, J. E., Robertson, M. J., Kiel, P. J., Sayar, H., Cox, E. A., Vance, G. H., Farag, S. S., Cripe, L. D. & Nelson, R. P., Feb 1 2015, In : American Journal of Hematology. 90, 2, p. 97-99 3 p.

Research output: Contribution to journalArticle

Cytarabine in relapsed acute myeloid leukemia

Hardesty, B. M. & Cripe, L. D., Apr 1 2012, In : Leukemia Research. 36, 4, p. 387-388 2 p.

Research output: Contribution to journalEditorial

Differences between Supportive Music and Imagery and Music Listening during Outpatient Chemotherapy and Potential Moderators of Treatment Effects

Burns, D. S., Meadows, A. N., Althouse, S., Perkins, S. M. & Cripe, L. D., Mar 9 2018, In : Journal of Music Therapy. 55, 1, p. 83-108 26 p.

Research output: Contribution to journalArticle

4 Scopus citations

Discussions of life expectancy moderate relationships between prognosis and anxiety or depression in men with advanced cancer

Cripe, L. D., Rawl, S. M., Schmidt, K. K., Tong, Y., Monahan, P. O. & Rand, K. L., Jan 1 2012, In : Journal of palliative medicine. 15, 1, p. 99-105 7 p.

Research output: Contribution to journalReview article

14 Scopus citations

Evidence of a role for functional heterogeneity in multidrug resistance transporters in clinical trials of P-glycoprotein modulation in acute myeloid leukemia

Marcelletti, J. F., Sikic, B. I., Cripe, L. D. & Paietta, E., Jan 2019, In : Cytometry Part B - Clinical Cytometry. 96, 1, p. 57-66 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Functional pathway analysis in acute myeloid leukemia using single cell network profiling assay: Effect of specimen source (bone marrow or peripheral blood) on assay readouts

Cesano, A., Rosen, D. B., O'Meara, P., Putta, S., Gayko, U., Spellmeyer, D. C., Cripe, L. D., Sun, Z., Uno, H., Litzow, M. R., Tallman, M. S. & Paietta, E., May 2012, In : Cytometry Part B - Clinical Cytometry. 82 B, 3, p. 158-172 15 p.

Research output: Contribution to journalArticle

24 Scopus citations

Functional Pathway Analysis Using SCNP of FLT3 Receptor Pathway Deregulation in AML Provides Prognostic Information Independent from Mutational Status

Cesano, A., Putta, S., Rosen, D. B., Cohen, A. C., Gayko, U., Mathi, K., Woronicz, J., Hawtin, R. E., Cripe, L., Sun, Z., Tallman, M. S. & Paietta, E., Feb 19 2013, In : PloS one. 8, 2, e56714.

Research output: Contribution to journalArticle

5 Scopus citations

Illness appraisal, religious coping, and psychological responses in men with advanced cancer

Rand, K. L., Cripe, L. D., Monahan, P. O., Tong, Y., Schmidt, K. & Rawl, S. M., Aug 2012, In : Supportive Care in Cancer. 20, 8, p. 1719-1728 10 p.

Research output: Contribution to journalArticle

27 Scopus citations
12 Scopus citations

Long-term outcome of NPM1 mutated acute myeloid leukemia: A single-institution experience

Sayar, S., Bashardoust, P., Cripe, L., Chakraborty, S. & Bai, S., Feb 1 2017, In : American Journal of Hematology. 92, 2, p. E17-E18

Research output: Contribution to journalLetter

2 Scopus citations

Medical Students’ Professionalism Narratives Reveal That Experiences With Death, Dying, or Palliative Care Are More Positive Than Other Experiences During Their Internal Medicine Clerkship

Cripe, L. D., Hedrick, D. G., Rand, K. L., Burns, D., Banno, D., Cottingham, A., Litzelman, D., Hoffmann, M. L., Martenyi, N. & Frankel, R. M., Feb 1 2017, In : American Journal of Hospice and Palliative Medicine. 34, 1, p. 79-84 6 p.

Research output: Contribution to journalArticle

4 Scopus citations
22 Scopus citations

Overexpression of IL-1 receptor accessory protein in stem and progenitor cells and outcome correlation in AML and MDS

Barreyro, L., Will, B., Bartholdy, B., Zhou, L., Todorova, T. I., Stanley, R. F., Ben-Neriah, S., Montagna, C., Parekh, S., Pellagatti, A., Boultwood, J., Paietta, E., Ketterling, R. P., Cripe, L., Fernandez, H. F., Greenberg, P. L., Tallman, M. S., Steidl, C., Mitsiades, C. S., Verma, A. & 1 others, Steidl, U., Aug 9 2012, In : Blood. 120, 6, p. 1290-1298 9 p.

Research output: Contribution to journalArticle

90 Scopus citations

Physicians in Postgraduate Training Characteristics and Support of Palliative Sedation for Existential Distress

Cripe, L. D., Perkins, S. M., Cottingham, A., Tong, Y., Kozak, M. A. & Mehta, R., Sep 1 2017, In : American Journal of Hospice and Palliative Medicine. 34, 8, p. 697-703 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Pilot study of erlotinib in patients with acute myeloid leukemia

Sayar, S., Czader, M., Amin, C., Cangany, M., Konig, H. & Cripe, L. D., Feb 1 2015, In : Leukemia Research. 39, 2, p. 170-172 3 p.

Research output: Contribution to journalArticle

3 Scopus citations

Predicting symptoms of anxiety and depression in patients living with advanced cancer: the differential roles of hope and optimism

Fischer, I. C., Cripe, L. D. & Rand, K. L., Oct 1 2018, In : Supportive Care in Cancer. 26, 10, p. 3471-3477 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Randomized, dose-escalation study of the p38α MAPK inhibitor SCIO-469 in patients with myelodysplastic syndrome

Sokol, L., Cripe, L., Kantarjian, H., Sekeres, M. A., Parmar, S., Greenberg, P., Goldberg, S. L., Bhushan, V., Shammo, J., Hohl, R., Verma, A., Garcia-Manero, G., Li, Y. P., Lowe, A., Zhu, J. & List, A. F., Apr 1 2013, In : Leukemia. 27, 4, p. 977-980 4 p.

Research output: Contribution to journalLetter

21 Scopus citations

Results from a randomized trial of salvage chemotherapy followed by lestaurtinib for patients with FLT3 mutant AML in first relapse

Levis, M., Ravandi, F., Wang, E. S., Baer, M. R., Perl, A., Coutre, S., Erba, H., Stuart, R. K., Baccarani, M., Cripe, L. D., Tallman, M. S., Meloni, G., Godley, L. A., Langston, A. A., Amadori, S., Lewis, I. D., Nagler, A., Stone, R., Yee, K., Advani, A. & 12 others, Douer, D., Wiktor-Jedrzejczak, W., Juliusson, G., Litzow, M. R., Petersdorf, S., Sanz, M., Kantarjian, H. M., Sato, T., Tremmel, L., Bensen-Kennedy, D. M., Small, D. & Smith, B. D., Mar 24 2011, In : Blood. 117, 12, p. 3294-3301 8 p.

Research output: Contribution to journalArticle

276 Scopus citations

REVEAL-1, a phase 2 dose regimen optimization study of vosaroxin in older poor-risk patients with previously untreated acute myeloid leukaemia

Stuart, R. K., Cripe, L. D., Maris, M. B., Cooper, M. A., Stone, R. M., Dakhil, S. R., Turturro, F., Stock, W., Mason, J., Shami, P. J., Strickland, S. A., Costa, L. J., Borthakur, G., Michelson, G. C., Fox, J. A., Leavitt, R. D. & Ravandi, F., Mar 1 2015, In : British journal of haematology. 168, 6, p. 796-805 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

The impact of design on research teams in health services

Sanematsu, H. & Cripe, L. D., Jan 1 2017, In : Information Design Journal. 23, 3, p. 310-318 9 p.

Research output: Contribution to journalArticle

Thrice weekly azacitidine does not improve hematological responses in lower-risk myelodysplastic syndromes: A study of the Hoosier Oncology Group

Sayar, H., Chan, R. J., Orschell, C. M., Chan, E. M., Yu, Z., Hood, D., Plett, A., Yang, Z., Hui, C. L., Nabinger, S. C., Kohlbacher, K. J., West, E. S., Walter, A., Sampson, C., Wu, J. & Cripe, L. D., Aug 1 2011, In : Leukemia Research. 35, 8, p. 1108-1110 3 p.

Research output: Contribution to journalArticle

7 Scopus citations

Trustworthiness

Cripe, L. D., Sep 1 2011, In : Journal of Clinical Oncology. 29, 25, p. 3483-3486 4 p.

Research output: Contribution to journalShort survey

1 Scopus citations

Very poor long-term survival in past and more recent studies for relapsed AML patients: The ECOG-ACRIN experience

Ganzel, C., Sun, Z., Cripe, L. D., Fernandez, H. F., Douer, D., Rowe, J. M., Paietta, E. M., Ketterling, R., O'Connell, M. J., Wiernik, P. H., Bennett, J. M., Litzow, M. R., Luger, S. M., Lazarus, H. M. & Tallman, M. S., Aug 2018, In : American Journal of Hematology. 93, 8, p. 1074-1081 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

“My Future is Now”: A Qualitative Study of Persons Living With Advanced Cancer

Cottingham, A. H., Cripe, L. D., Rand, K. L. & Frankel, R. M., Apr 1 2018, In : American Journal of Hospice and Palliative Medicine. 35, 4, p. 640-646 7 p.

Research output: Contribution to journalArticle

6 Scopus citations