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  • Naga Chalasani
2019

Admission plasma uromodulin and the risk of acute kidney injury in hospitalized patients with cirrhosis: a pilot study

Patidar, K. R., Garimella, P. S., Macedo, E., Slaven, J. E., Ghabril, M. S., Weber, R. E., Anderson, M., Orman, E. S., Nephew, L. D., Desai, A. P., Chalasani, N. P. & El-Achkar, T. M., Oct 1 2019, In : American journal of physiology. Gastrointestinal and liver physiology. 317, 4, p. G447-G452

Research output: Contribution to journalArticle

Advice Regarding Alcohol Use by Individuals With Nonalcoholic Fatty Liver Disease: Primum non nocere

Dunn, W. & Chalasani, N., Jan 2019, In : Hepatology. 69, 1, p. 9-11 3 p.

Research output: Contribution to journalEditorial

Alcohol abstinence does not fully reverse abnormalities of mucosal-associated invariant T cells in the blood of patients with alcoholic hepatitis

Li, W., Lin, E. L., Liangpunsakul, S., Lan, J., Chalasani, S., Rane, S., Puri, P., Kamath, P. S., Sanyal, A. J., Shah, V. H., Radaeva, S., Crabb, D. W., Chalasani, N. & Yu, Q., Jun 1 2019, In : Clinical and translational gastroenterology. 10, 6, e-00052.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury

Drug-Induced Liver Injury Network (DILIN) investigators & International DILI consortium (iDILIC), May 2019, In : Gastroenterology. 156, 6, p. 1707-1716.e2

Research output: Contribution to journalArticle

20 Scopus citations

Association of Histologic Disease Activity With Progression of Nonalcoholic Fatty Liver Disease

Nonalcoholic Steatohepatitis Clinical Research Network, Oct 2 2019, In : JAMA Network Open. 2, 10, p. e1912565

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Black Adult Patients With Acute Liver Failure Are Sicker and More Likely to Undergo Liver Transplantation Than White Patients

Nephew, L., Zia, Z., Ghabril, M., Orman, E., Lammert, C. & Chalasani, N., Nov 1 2019, In : Liver Transplantation. 25, 11, p. 1634-1641 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Candidate biomarkers for the diagnosis and prognosis of drug-induced liver injury: An international collaborative effort

Church, R. J., Kullak-Ublick, G. A., Aubrecht, J., Bonkovsky, H. L., Chalasani, N., Fontana, R. J., Goepfert, J. C., Hackman, F., King, N. M. P., Kirby, S., Kirby, P., Marcinak, J., Ormarsdottir, S., Schomaker, S. J., Schuppe-Koistinen, I., Wolenski, F., Arber, N., Merz, M., Sauer, J. M., Andrade, R. J. & 3 others, van Bömmel, F., Poynard, T. & Watkins, P. B., Feb 1 2019, In : Hepatology. 69, 2, p. 760-773 14 p.

Research output: Contribution to journalArticle

45 Scopus citations

Characteristics, aetiologies and trends of hepatocellular carcinoma in patients without cirrhosis: a United States multicentre study

Gawrieh, S., Dakhoul, L., Miller, E., Scanga, A., deLemos, A., Kettler, C., Burney, H., Liu, H., Abu-Sbeih, H., Chalasani, N. & Wattacheril, J., Oct 1 2019, In : Alimentary Pharmacology and Therapeutics. 50, 7, p. 809-821 13 p.

Research output: Contribution to journalArticle

8 Scopus citations

Consensus: guidelines: best practices for detection, assessment and management of suspected acute drug-induced liver injury during clinical trials in patients with nonalcoholic steatohepatitis

Regev, A., Palmer, M., Avigan, M. I., Dimick-Santos, L., Treem, W. R., Marcinak, J. F., Seekins, D., Krishna, G., Anania, F. A., Freston, J. W., Lewis, J. H., Sanyal, A. J. & Chalasani, N., Mar 2019, In : Alimentary Pharmacology and Therapeutics. 49, 6, p. 702-713 12 p.

Research output: Contribution to journalReview article

4 Scopus citations

Correction: Cytokine profiles in acute liver injury-Results from the US Drug-Induced Liver Injury Network (DILIN) and the Acute Liver Failure Study Group (PLoS ONE (2018) 13:10 (e0206389) DOI: 10.1371/journal.pone.0206389)

US Drug-Induced Liver Injury Network and the Acute Liver Failure Study Group, Feb 2019, In : PloS one. 14, 2, e0212394.

Research output: Contribution to journalComment/debate

Open Access

Development and Validation of a Model Consisting of Comorbidity Burden to Calculate Risk of Death Within 6 Months for Patients With Suspected Drug-Induced Liver Injury

Ghabril, M., Gu, J., Yoder, L., Corbito, L., Ringel, A., Beyer, C. D., Vuppalanchi, R., Barnhart, H., Hayashi, P. H. & Chalasani, N., Nov 2019, In : Gastroenterology. 157, 5, p. 1245-1252.e3

Research output: Contribution to journalArticle

Development and Validation of a Model to Predict Acute Kidney Injury in Hospitalized Patients With Cirrhosis

Patidar, K. R., Xu, C., Shamseddeen, H., Cheng, Y. W., Ghabril, M. S., Mukthinuthalapati, V. V. P. K., Fricker, Z. P., Akinyeye, S., Nephew, L. D., Desai, A. P., Anderson, M., El-Achkar, T. M., Chalasani, N. P. & Orman, E. S., Sep 1 2019, In : Clinical and translational gastroenterology. 10, 9, p. e00075

Research output: Contribution to journalArticle

Open Access

Diagnostic Accuracy of Noninvasive Fibrosis Models to Detect Change in Fibrosis Stage

NASH Clinical Research Network, Aug 2019, In : Clinical Gastroenterology and Hepatology. 17, 9, p. 1877-1885.e5

Research output: Contribution to journalArticle

17 Scopus citations

Drug-induced liver injury

Chalasani, N. & Crabb, D., Jan 1 2019, In : Gastroenterology and Hepatology. 15, 1, p. 35-37 3 p.

Research output: Contribution to journalComment/debate

Drug-induced liver injury

Andrade, R. J., Chalasani, N., Björnsson, E. S., Suzuki, A., Kullak-Ublick, G. A., Watkins, P. B., Devarbhavi, H., Merz, M., Lucena, M. I., Kaplowitz, N. & Aithal, G. P., Dec 1 2019, In : Nature Reviews Disease Primers. 5, 1, 58.

Research output: Contribution to journalArticle

4 Scopus citations
3 Scopus citations

Early predictors of outcomes of hospitalization for cirrhosis and assessment of the impact of race and ethnicity at safety-net hospitals

Mukthinuthalapati, V. V. P. K., Akinyeye, S., Fricker, Z. P., Syed, M., Orman, E. S., Nephew, L., Vilar-Gomez, E., Slaven, J., Chalasani, N., Balakrishnan, M., Long, M. T., Attar, B. M. & Ghabril, M., Mar 1 2019, In : PLoS ONE. 14, 3, e0211811.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Expanding the Donor Pool With the Use of Extended Criteria Donation After Circulatory Death Livers

Mihaylov, P., Mangus, R., Ekser, B., Cabrales, A., Timsina, L., Fridell, J., Lacerda, M., Ghabril, M., Nephew, L., Chalasani, N. & Kubal, C. A., Jan 1 2019, In : Liver Transplantation.

Research output: Contribution to journalArticle

9 Scopus citations

Factors Associated With Histologic Response in Adult Patients With Nonalcoholic Steatohepatitis

Loomba, R., Sanyal, A. J., Kowdley, K. V., Terrault, N., Chalasani, N. P., Abdelmalek, M. F., McCullough, A. J., Shringarpure, R., Ferguson, B., Lee, L., Chen, J., Liberman, A., Shapiro, D. & Neuschwander-Tetri, B. A., Jan 2019, In : Gastroenterology. 156, 1, p. 88-95.e5

Research output: Contribution to journalArticle

6 Scopus citations

Haptoglobin 2 Allele is Associated with Histologic Response to Vitamin E in Subjects with Nonalcoholic Steatohepatitis

Banini, B. A., Cazanave, S. C., Yates, K. P., Asgharpour, A., Vincent, R., Mirshahi, F., Le, P., Contos, M. J., Tonascia, J., Chalasani, N. P., Kowdley, K. V., McCullough, A. J., Behling, C. A., Schwimmer, J. B., Lavine, J. E. & Sanyal, A. J., Nov 1 2019, In : Journal of Clinical Gastroenterology. 53, 10, p. 750-758 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Histologic Findings of Advanced Fibrosis and Cirrhosis in Patients With Nonalcoholic Fatty Liver Disease Who Have Normal Aminotransferase Levels

and the NASH Clinical Research Network, Oct 1 2019, In : The American journal of gastroenterology. 114, 10, p. 1626-1635 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Impact of obeticholic acid on the lipoprotein profile in patients with non-alcoholic steatohepatitis

for the NASH CRN, Jan 1 2019, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Importance of Hepatitis C Virus RNA Testing in Patients with Suspected Drug-Induced Liver Injury

Ahmad, J., Reddy, K. R., Tillmann, H. L., Hayashi, P. H., Chalasani, N., Fontana, R. J., Navarro, V. J., Stolz, A., Barnhart, H., Cloherty, G. A. & Hoofnagle, J. H., Sep 15 2019, In : Digestive diseases and sciences. 64, 9, p. 2645-2652 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Increasing economic burden in hospitalized patients with cirrhosis: Analysis of a national database

Desai, A. P., Mohan, P., Nokes, B., Sheth, D., Knapp, S., Boustani, M., Chalasani, N., Fallon, M. B. & Calhoun, E. A., Jan 1 2019, In : Clinical and translational gastroenterology. 10, 7, e-00062.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Is Fasting Necessary for Individuals with Nonalcoholic Fatty Liver Disease to Undergo Vibration-Controlled Transient Elastography?

Vuppalanchi, R., Weber, R., Russell, S., Gawrieh, S., Samala, N., Slaven, J. E., Harden, L. & Chalasani, N., Jun 1 2019, In : American Journal of Gastroenterology. 114, 6, p. 995-997 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Letter: metformin reduces the risk of hepatocellular carcinoma in diabetic patients. Authors' reply

Vilar-Gomez, E. & Chalasani, N., Oct 1 2019, In : Alimentary Pharmacology and Therapeutics. 50, 7, p. 838-839 2 p.

Research output: Contribution to journalLetter

1 Scopus citations
7 Scopus citations
7 Scopus citations

Nonalcoholic Fatty Liver Disease and the Heart: JACC State-of-the-Art Review

Stahl, E. P., Dhindsa, D. S., Lee, S. K., Sandesara, P. B., Chalasani, N. P. & Sperling, L. S., Mar 5 2019, In : Journal of the American College of Cardiology. 73, 8, p. 948-963 16 p.

Research output: Contribution to journalReview article

18 Scopus citations

Novel HLA class I alleles outside the extended DR3 haplotype are protective against autoimmune hepatitis

Lammert, C., McKinnon, E. J., Chalasani, N. & Phillips, E. J., Jun 1 2019, In : Clinical and translational gastroenterology. 10, 6, e-00032.

Research output: Contribution to journalArticle

Open Access

Older Age and Disease Duration Are Highly Associated with Hepatocellular Carcinoma in Patients with Autoimmune Hepatitis

Dakhoul, L., Jones, K. R., Gawrieh, S., Ghabril, M., McShane, C., Vuppalanchi, R., Vilar-Gomez, E., Nephew, L., Chalasani, N. & Lammert, C., Jun 15 2019, In : Digestive diseases and sciences. 64, 6, p. 1705-1710 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Oxidized Derivatives of Linoleic Acid in Pediatric Metabolic Syndrome: Is Their Pathogenic Role Modulated by the Genetic Background and the Gut Microbiota?

Tricò, D., Di Sessa, A., Caprio, S., Chalasani, N., Liu, W., Liang, T., Graf, J., Herzog, R. I., Johnson, C. D., Umano, G. R., Feldstein, A. E. & Santoro, N., Jan 10 2019, In : Antioxidants and Redox Signaling. 30, 2, p. 241-250 10 p.

Research output: Contribution to journalArticle

7 Scopus citations
4 Scopus citations

Post hoc analyses of surrogate markers of non-alcoholic fatty liver disease (NAFLD) and liver fibrosis in patients with type 2 diabetes in a digitally supported continuous care intervention: An open-label, non-randomised controlled study

Vilar-Gomez, E., Athinarayanan, S. J., Adams, R. N., Hallberg, S. J., Bhanpuri, N. H., McKenzie, A. L., Campbell, W. W., McCarter, J. P., Phinney, S. D., Volek, J. S. & Chalasani, N., Feb 1 2019, In : BMJ open. 9, 2, 023597.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Prioritization of Therapeutic Targets and Trial Design in Cirrhotic Portal Hypertension

Abraldes, J. G., Trebicka, J., Chalasani, N., D’Amico, G., Rockey, D. C., Shah, V. H., Bosch, J. & Garcia-Tsao, G., Mar 2019, In : Hepatology. 69, 3, p. 1287-1299 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Randomized Controlled Trial of a Leucine-Metformin-Sildenafil Combination (NS-0200) on Weight and Metabolic Parameters

Zemel, M. B., Kolterman, O., Rinella, M., Vuppalanchi, R., Flores, O., Barritt, A. S., Siddiqui, M. & Chalasani, N., Jan 1 2019, In : Obesity. 27, 1, p. 59-67 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Relationship between resolution of non-alcoholic steatohepatitis and changes in lipoprotein sub-fractions: a post-hoc analysis of the PIVENS trial

the NASH Clinical Research Network, May 2019, In : Alimentary Pharmacology and Therapeutics. 49, 9, p. 1205-1213 9 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Relationship between three commonly used non-invasive fibrosis biomarkers and improvement in fibrosis stage in patients with non-alcoholic steatohepatitis

Chalasani, N., Abdelmalek, M. F., Loomba, R., Kowdley, K. V., McCullough, A. J., Dasarathy, S., Neuschwander-Tetri, B. A., Terrault, N., Ferguson, B., Shringarpure, R., Shapiro, D. & Sanyal, A. J., May 2019, In : Liver International. 39, 5, p. 924-932 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Reply

Vilar-Gomez, E. & Chalasani, N., Jan 1 2019, In : Hepatology. 70, 2, 1 p.

Research output: Contribution to journalLetter

Reply

Vuppalanchi, R. & Chalasani, N., Jul 2019, In : Hepatology. 70, 1, p. 445-446 2 p.

Research output: Contribution to journalLetter

Open Access
8 Scopus citations

Trends in Characteristics, Mortality, and Other Outcomes of Patients with Newly Diagnosed Cirrhosis

Orman, E. S., Roberts, A., Ghabril, M., Nephew, L., Desai, A., Patidar, K. & Chalasani, N., Jan 1 2019, In : JAMA Network Open.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Vibration-Controlled Transient Elastography to Assess Fibrosis and Steatosis in Patients With Nonalcoholic Fatty Liver Disease

NASH Clinical Research Network, Jan 2019, In : Clinical Gastroenterology and Hepatology. 17, 1, p. 156-163.e2

Research output: Contribution to journalArticle

45 Scopus citations
2018

A dedicated paracentesis clinic decreases healthcare utilization for serial paracenteses in decompensated cirrhosis

Cheng, Y. W., Sandrasegaran, K., Cheng, K., Shah, A., Ghabril, M., Berry, W., Lammert, C., Chalasani, N. & Orman, E. S., Aug 1 2018, In : Abdominal Radiology. 43, 8, p. 2190-2197 8 p.

Research output: Contribution to journalArticle

Automated assessment of steatosis in murine fatty liver

Sethunath, D., Morusu, S., Tuceryan, M., Cummings, O., Zhang, H., Yin, X-M., Vanderbeck, S., Chalasani, N. & Gawrieh, S., May 1 2018, In : PLoS One. 13, 5, e0197242.

Research output: Contribution to journalArticle

1 Scopus citations

Celecoxib-induced Liver Injury

Mukthinuthalapati, P. K., Fontana, R. J., Vuppalanchi, R., Chalasani, N. & Ghabril, M., Jan 1 2018, In : Journal of Clinical Gastroenterology. 52, 2, p. 114-122 9 p.

Research output: Contribution to journalReview article

4 Scopus citations

Class II Human Leukocyte Antigen Epitope Mismatch Predicts De Novo Donor-Specific Antibody Formation After Liver Transplantation

Kubal, C. A., Mangus, R., Ekser, B., Mihaylov, P., Ceballos, B., Higgins, N., Chalasani, N., Ghabril, M., Nephew, L. & Lobashevsky, A., Aug 2018, In : Liver Transplantation. 24, 8, p. 1101-1108 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Clinical and metabolic effects associated with weight changes and obeticholic acid in non-alcoholic steatohepatitis

for the NASH CRN, Mar 2018, In : Alimentary Pharmacology and Therapeutics. 47, 5, p. 645-656 12 p.

Research output: Contribution to journalArticle

16 Scopus citations