Find Publications

Search in all content

Filters for Publications

Search concepts
Selected Filters

Publication Year

  • 2020
  • 2019
  • 2018
  • 2017
  • 2016

Author

  • Naga Chalasani
Article

A dedicated paracentesis clinic decreases healthcare utilization for serial paracenteses in decompensated cirrhosis

Cheng, Y. W., Sandrasegaran, K., Cheng, K., Shah, A., Ghabril, M., Berry, W., Lammert, C., Chalasani, N. & Orman, E. S., Aug 1 2018, In : Abdominal Radiology. 43, 8, p. 2190-2197 8 p.

Research output: Contribution to journalArticle

Admission plasma uromodulin and the risk of acute kidney injury in hospitalized patients with cirrhosis: a pilot study

Patidar, K. R., Garimella, P. S., Macedo, E., Slaven, J. E., Ghabril, M. S., Weber, R. E., Anderson, M., Orman, E. S., Nephew, L. D., Desai, A. P., Chalasani, N. P. & El-Achkar, T. M., Oct 1 2019, In : American journal of physiology. Gastrointestinal and liver physiology. 317, 4, p. G447-G452

Research output: Contribution to journalArticle

Alcohol abstinence ameliorates the dysregulated immune profiles in patients with alcoholic hepatitis: A prospective observational study

Li, W., Amet, T., Xing, Y., Yang, D., Liangpunsakul, S., Puri, P., Kamath, P. S., Sanyal, A. J., Shah, V. H., Katz, B. P., Radaeva, S., Crabb, D. W., Chalasani, N. & Yu, Q., Aug 2017, In : Hepatology. 66, 2, p. 575-590 16 p.

Research output: Contribution to journalArticle

11 Scopus citations

Alcohol abstinence does not fully reverse abnormalities of mucosal-associated invariant T cells in the blood of patients with alcoholic hepatitis

Li, W., Lin, E. L., Liangpunsakul, S., Lan, J., Chalasani, S., Rane, S., Puri, P., Kamath, P. S., Sanyal, A. J., Shah, V. H., Radaeva, S., Crabb, D. W., Chalasani, N. & Yu, Q., Jun 1 2019, In : Clinical and translational gastroenterology. 10, 6, e-00052.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Alcohol Rehabilitation Within 30 Days of Hospital Discharge Is Associated With Reduced Readmission, Relapse, and Death in Patients With Alcoholic Hepatitis

Peeraphatdit, T. B., Kamath, P. S., Karpyak, V. M., Davis, B., Desai, V., Liangpunsakul, S., Sanyal, A., Chalasani, N., Shah, V. H. & Simonetto, D. A., Feb 2020, In : Clinical Gastroenterology and Hepatology. 18, 2, p. 477-485.e5

Research output: Contribution to journalArticle

2 Scopus citations

A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury

Drug-Induced Liver Injury Network (DILIN) investigators & International DILI consortium (iDILIC), May 2019, In : Gastroenterology. 156, 6, p. 1707-1716.e2

Research output: Contribution to journalArticle

20 Scopus citations

An exploratory genome-wide analysis of genetic risk for alcoholic hepatitis

for the TREAT Consortium, Nov 2 2017, In : Scandinavian Journal of Gastroenterology. 52, 11, p. 1263-1269 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Apolipoprotein B and PNPLA3 Double Heterozygosity in a Father–Son Pair With Advanced Nonalcoholic Fatty Liver Disease

Jansson-Knodell, C. L., Gawrieh, S., McIntyre, A. D., Liang, T., Hegele, R. A. & Chalasani, N., Jan 1 2020, In : Hepatology. 71, 1, p. 383-385 3 p.

Research output: Contribution to journalArticle

Association of Histologic Disease Activity With Progression of Nonalcoholic Fatty Liver Disease

Nonalcoholic Steatohepatitis Clinical Research Network, Oct 2 2019, In : JAMA Network Open. 2, 10, p. e1912565

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study

International Drug-Induced Liver Injury Consortium, Drug-Induced Liver Injury Network Investigators, and International Serious Adverse Events Consortium, Apr 1 2017, In : Gastroenterology. 152, 5, p. 1078-1089 12 p.

Research output: Contribution to journalArticle

81 Scopus citations

Automated assessment of steatosis in murine fatty liver

Sethunath, D., Morusu, S., Tuceryan, M., Cummings, O., Zhang, H., Yin, X-M., Vanderbeck, S., Chalasani, N. & Gawrieh, S., May 1 2018, In : PLoS One. 13, 5, e0197242.

Research output: Contribution to journalArticle

1 Scopus citations

Automated quantification and architectural pattern detection of hepatic fibrosis in NAFLD

Gawrieh, S., Sethunath, D., Cummings, O. W., Kleiner, D. E., Vuppalanchi, R., Chalasani, N. & Tuceryan, M., Aug 2020, In : Annals of Diagnostic Pathology. 47, 151518.

Research output: Contribution to journalArticle

Azathioprine and 6-Mercaptopurine-induced Liver Injury

DILIN Investigators, 2017, In : Journal of Clinical Gastroenterology. 51, 1, p. 63-69 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Black Adult Patients With Acute Liver Failure Are Sicker and More Likely to Undergo Liver Transplantation Than White Patients

Nephew, L., Zia, Z., Ghabril, M., Orman, E., Lammert, C. & Chalasani, N., Nov 1 2019, In : Liver Transplantation. 25, 11, p. 1634-1641 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Candidate biomarkers for the diagnosis and prognosis of drug-induced liver injury: An international collaborative effort

Church, R. J., Kullak-Ublick, G. A., Aubrecht, J., Bonkovsky, H. L., Chalasani, N., Fontana, R. J., Goepfert, J. C., Hackman, F., King, N. M. P., Kirby, S., Kirby, P., Marcinak, J., Ormarsdottir, S., Schomaker, S. J., Schuppe-Koistinen, I., Wolenski, F., Arber, N., Merz, M., Sauer, J. M., Andrade, R. J. & 3 others, van Bömmel, F., Poynard, T. & Watkins, P. B., Feb 1 2019, In : Hepatology. 69, 2, p. 760-773 14 p.

Research output: Contribution to journalArticle

45 Scopus citations

Characteristics, aetiologies and trends of hepatocellular carcinoma in patients without cirrhosis: a United States multicentre study

Gawrieh, S., Dakhoul, L., Miller, E., Scanga, A., deLemos, A., Kettler, C., Burney, H., Liu, H., Abu-Sbeih, H., Chalasani, N. & Wattacheril, J., Oct 1 2019, In : Alimentary Pharmacology and Therapeutics. 50, 7, p. 809-821 13 p.

Research output: Contribution to journalArticle

8 Scopus citations

Child-Turcotte-Pugh Class is Best at Stratifying Risk in Variceal Hemorrhage: Analysis of a US Multicenter Prospective Study

for the Vapreotide Study Group, Jan 1 2017, In : Journal of Clinical Gastroenterology. 51, 5, p. 446-453 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

Class II Human Leukocyte Antigen Epitope Mismatch Predicts De Novo Donor-Specific Antibody Formation After Liver Transplantation

Kubal, C. A., Mangus, R., Ekser, B., Mihaylov, P., Ceballos, B., Higgins, N., Chalasani, N., Ghabril, M., Nephew, L. & Lobashevsky, A., Aug 2018, In : Liver Transplantation. 24, 8, p. 1101-1108 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Clinical and metabolic effects associated with weight changes and obeticholic acid in non-alcoholic steatohepatitis

for the NASH CRN, Mar 2018, In : Alimentary Pharmacology and Therapeutics. 47, 5, p. 645-656 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

Clinical Characteristics and Adverse Impact of Hepatotoxicity due to Immune Checkpoint Inhibitors

Miller, E. D., Abu-Sbeih, H., Styskel, B., Nogueras Gonzalez, G. M., Blechacz, B., Naing, A. & Chalasani, N., Feb 1 2020, In : The American journal of gastroenterology. 115, 2, p. 251-261 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Concomitant Psychiatric and Nonalcohol-Related Substance Use Disorders Among Hospitalized Patients with Alcoholic Liver Disease in the United States

the Translational Research and Evolving Alcoholic Hepatitis Treatment Consortium, Feb 1 2018, In : Alcoholism: Clinical and Experimental Research. 42, 2, p. 397-402 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Cytokine profiles in acute liver injury—Results from the US Drug-Induced Liver Injury Network (DILIN) and the Acute Liver Failure Study Group

Bonkovsky, H. L., Barnhart, H. X., Foureau, D. M., Steuerwald, N., Lee, W. M., Gu, J., Fontana, R. J., Hayashi, P. J., Chalasani, N., Navarro, V. M., Odin, J., Stolz, A., Watkins, P. B. & Serrano, J., Oct 2018, In : PloS one. 13, 10, e0206389.

Research output: Contribution to journalArticle

8 Scopus citations

Death and liver transplantation within 2 years of onset of drug-induced liver injury

for the Drug-Induced Liver Injury Network (DILIN) Investigators, Oct 2017, In : Hepatology. 66, 4, p. 1275-1285 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

Development and Validation of a Model Consisting of Comorbidity Burden to Calculate Risk of Death Within 6 Months for Patients With Suspected Drug-Induced Liver Injury

Ghabril, M., Gu, J., Yoder, L., Corbito, L., Ringel, A., Beyer, C. D., Vuppalanchi, R., Barnhart, H., Hayashi, P. H. & Chalasani, N., Nov 2019, In : Gastroenterology. 157, 5, p. 1245-1252.e3

Research output: Contribution to journalArticle

Development and Validation of a Model to Predict Acute Kidney Injury in Hospitalized Patients With Cirrhosis

Patidar, K. R., Xu, C., Shamseddeen, H., Cheng, Y. W., Ghabril, M. S., Mukthinuthalapati, V. V. P. K., Fricker, Z. P., Akinyeye, S., Nephew, L. D., Desai, A. P., Anderson, M., El-Achkar, T. M., Chalasani, N. P. & Orman, E. S., Sep 1 2019, In : Clinical and translational gastroenterology. 10, 9, p. e00075

Research output: Contribution to journalArticle

Open Access

Development of a modified lymphocyte transformation test for diagnosing drug-induced liver injury associated with an adaptive immune response

Whritenour, J., Ko, M., Zong, Q., Wang, J., Tartaro, K., Schneider, P., Olson, E., Van Volkenburg, M., Serrano, J., Hayashi, P., Fontana, R., Chalasani, N. & Bonkovsky, H. L., Jan 1 2017, In : Journal of Immunotoxicology. 14, 1, p. 31-38 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Diagnostic Accuracy of Noninvasive Fibrosis Models to Detect Change in Fibrosis Stage

NASH Clinical Research Network, Aug 2019, In : Clinical Gastroenterology and Hepatology. 17, 9, p. 1877-1885.e5

Research output: Contribution to journalArticle

17 Scopus citations

Distinctive Features and Outcomes of Hepatocellular Carcinoma in Patients With Alcohol-Related Liver Disease: A US Multicenter Study

deLemos, A., Patel, M., Gawrieh, S., Burney, H., Dakhoul, L., Miller, E., Scanga, A., Kettler, C., Liu, H., Roche, P., Wattacheril, J. & Chalasani, N., Mar 1 2020, In : Clinical and translational gastroenterology. 11, 3, p. e00139

Research output: Contribution to journalArticle

Open Access

Drug-induced liver injury

Andrade, R. J., Chalasani, N., Björnsson, E. S., Suzuki, A., Kullak-Ublick, G. A., Watkins, P. B., Devarbhavi, H., Merz, M., Lucena, M. I., Kaplowitz, N. & Aithal, G. P., Dec 1 2019, In : Nature Reviews Disease Primers. 5, 1, 58.

Research output: Contribution to journalArticle

4 Scopus citations

Dynamic MTORC1-TFEB feedback signaling regulates hepatic autophagy, steatosis and liver injury in long-term nutrient oversupply

Zhang, H., Yan, S., Khambu, B., Ma, F., Li, Y., Chen, X., Martina, J. A., Puertollano, R., Li, Y., Chalasani, N. & Yin, X. M., Oct 3 2018, In : Autophagy. 14, 10, p. 1779-1795 17 p.

Research output: Contribution to journalArticle

10 Scopus citations

Early predictors of outcomes of hospitalization for cirrhosis and assessment of the impact of race and ethnicity at safety-net hospitals

Mukthinuthalapati, V. V. P. K., Akinyeye, S., Fricker, Z. P., Syed, M., Orman, E. S., Nephew, L., Vilar-Gomez, E., Slaven, J., Chalasani, N., Balakrishnan, M., Long, M. T., Attar, B. M. & Ghabril, M., Mar 1 2019, In : PLoS ONE. 14, 3, e0211811.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Effects of Age, Sex, Body Weight, and Quantity of Alcohol Consumption on Occurrence and Severity of Alcoholic Hepatitis

Translational Research and Evolving Alcoholic Hepatitis Treatment Consortium & Translational Research and Evolving Alcoholic Hepatitis Treatment Consortium, Dec 1 2016, In : Clinical Gastroenterology and Hepatology. 14, 12, p. 1831-1838.e3

Research output: Contribution to journalArticle

19 Scopus citations

Effects of Belapectin, an Inhibitor of Galectin-3, in Patients With Nonalcoholic Steatohepatitis With Cirrhosis and Portal Hypertension

The Belapectin (GR-MD-02) Study Investigators, Apr 2020, In : Gastroenterology. 158, 5, p. 1334-1345.e5

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Expanding the Donor Pool With the Use of Extended Criteria Donation After Circulatory Death Livers

Mihaylov, P., Mangus, R., Ekser, B., Cabrales, A., Timsina, L., Fridell, J., Lacerda, M., Ghabril, M., Nephew, L., Chalasani, N. & Kubal, C. A., Jan 1 2019, In : Liver Transplantation.

Research output: Contribution to journalArticle

9 Scopus citations

Factors Associated With Histologic Response in Adult Patients With Nonalcoholic Steatohepatitis

Loomba, R., Sanyal, A. J., Kowdley, K. V., Terrault, N., Chalasani, N. P., Abdelmalek, M. F., McCullough, A. J., Shringarpure, R., Ferguson, B., Lee, L., Chen, J., Liberman, A., Shapiro, D. & Neuschwander-Tetri, B. A., Jan 2019, In : Gastroenterology. 156, 1, p. 88-95.e5

Research output: Contribution to journalArticle

6 Scopus citations

Features of Autoimmune Hepatitis in Patients With Drug-induced Liver Injury

de Boer, Y. S., Kosinski, A. S., Urban, T. J., Zhao, Z., Long, N., Chalasani, N., Kleiner, D. E. & Hoofnagle, J. H., Jan 1 2017, In : Clinical Gastroenterology and Hepatology. 15, 1, p. 103-112.e2

Research output: Contribution to journalArticle

52 Scopus citations

Febuxostat-induced acute liver injury

Bohm, M., Vuppalanchi, R., Chalasani, N., Fontana, R. J., Watkins, P. B., Bonkovsky, H. L., Davern, T., Serrano, J. & Rochon, J., Mar 1 2016, In : Hepatology. 63, 3, p. 1047-1049 3 p.

Research output: Contribution to journalArticle

11 Scopus citations

Fibrosis Severity as a Determinant of Cause-Specific Mortality in Patients With Advanced Nonalcoholic Fatty Liver Disease: A Multi-National Cohort Study

Vilar-Gomez, E., Calzadilla-Bertot, L., Wai-Sun Wong, V., Castellanos, M., Aller-de la Fuente, R., Metwally, M., Eslam, M., Gonzalez-Fabian, L., Alvarez-Quiñones Sanz, M., Conde-Martin, A. F., De Boer, B., McLeod, D., Hung Chan, A. W., Chalasani, N., George, J., Adams, L. A. & Romero-Gomez, M., Aug 2018, In : Gastroenterology. 155, 2, p. 443-457.e17

Research output: Contribution to journalArticle

98 Scopus citations

Genetic Variants Associated with Obesity and Insulin Resistance in Hispanic Boys with Nonalcoholic Fatty Liver Disease

Rausch, J. C., Lavine, J. E., Chalasani, N., Guo, X., Kwon, S., Schwimmer, J. B., Molleston, J. P., Loomba, R., Brunt, E. M., Chen, Y. D. I., Goodarzi, M. O., Taylor, K. D., Yates, K. P. & Rotter, J. I., May 1 2018, In : Journal of pediatric gastroenterology and nutrition. 66, 5, p. 789-796 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Genome-Wide Associations Related to Hepatic Histology in Nonalcoholic Fatty Liver Disease in Hispanic Boys

Wattacheril, J., Lavine, J. E., Chalasani, N. P., Guo, X., Kwon, S., Schwimmer, J., Molleston, J. P., Loomba, R., Brunt, E. M., Chen, Y. D. I., Goodarzi, M. O., Taylor, K. D., Yates, K. P., Tonascia, J. & Rotter, J. I., Nov 2017, In : Journal of Pediatrics. 190, p. 100-107.e2

Research output: Contribution to journalArticle

11 Scopus citations

Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease

Ji, S. G., Juran, B. D., Mucha, S., Folseraas, T., Jostins, L., Melum, E., Kumasaka, N., Atkinson, E. J., Schlicht, E. M., Liu, J. Z., Shah, T., Gutierrez-Achury, J., Boberg, K. M., Bergquist, A., Vermeire, S., Eksteen, B., Durie, P. R., Farkkila, M., Müller, T., Schramm, C. & 50 others, Sterneck, M., Weismüller, T. J., Gotthardt, D. N., Ellinghaus, D., Braun, F., Teufel, A., Laudes, M., Lieb, W., Jacobs, G., Beuers, U., Weersma, R. K., Wijmenga, C., Marschall, H. U., Milkiewicz, P., Pares, A., Kontula, K., Chazouillères, O., Invernizzi, P., Goode, E., Spiess, K., Moore, C., Sambrook, J., Ouwehand, W. H., Roberts, D. J., Danesh, J., Floreani, A., Gulamhusein, A. F., Eaton, J. E., Schreiber, S., Coltescu, C., Bowlus, C. L., Luketic, V. A., Odin, J. A., Chopra, K. B., Kowdley, K. V., Chalasani, N., Manns, M. P., Srivastava, B., Mells, G., Sandford, R. N., Alexander, G., Gaffney, D. J., Chapman, R. W., Hirschfield, G. M., De Andrade, M., Rushbrook, S. M., Franke, A., Karlsen, T. H., Lazaridis, K. N. & Anderson, C. A., Jan 31 2017, In : Nature genetics. 49, 2, p. 269-273 5 p.

Research output: Contribution to journalArticle

60 Scopus citations

Haptoglobin 2 Allele is Associated with Histologic Response to Vitamin E in Subjects with Nonalcoholic Steatohepatitis

Banini, B. A., Cazanave, S. C., Yates, K. P., Asgharpour, A., Vincent, R., Mirshahi, F., Le, P., Contos, M. J., Tonascia, J., Chalasani, N. P., Kowdley, K. V., McCullough, A. J., Behling, C. A., Schwimmer, J. B., Lavine, J. E. & Sanyal, A. J., Nov 1 2019, In : Journal of Clinical Gastroenterology. 53, 10, p. 750-758 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Heavy Consumption of Alcohol is Not Associated With Worse Outcomes in Patients With Idiosyncratic Drug-induced Liver Injury Compared to Non-Drinkers

United States Drug Induced Liver Injury Network, May 2018, In : Clinical Gastroenterology and Hepatology. 16, 5, p. 722-729.e2

Research output: Contribution to journalArticle

6 Scopus citations

Histologic Findings of Advanced Fibrosis and Cirrhosis in Patients With Nonalcoholic Fatty Liver Disease Who Have Normal Aminotransferase Levels

and the NASH Clinical Research Network, Oct 1 2019, In : The American journal of gastroenterology. 114, 10, p. 1626-1635 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Identification and Characterization of Fenofibrate-Induced Liver Injury

Ahmad, J., Odin, J. A., Hayashi, P. H., Chalasani, N., Fontana, R. J., Barnhart, H., Cirulli, E. T., Kleiner, D. E. & Hoofnagle, J. H., Dec 1 2017, In : Digestive diseases and sciences. 62, 12, p. 3596-3604 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Idiosyncratic Drug Induced Liver Injury in African-Americans is Associated with Greater Morbidity and Mortality Compared to Caucasians

Chalasani, N., Reddy, K. R. K., Fontana, R. J., Barnhart, H., Gu, J., Hayashi, P. H., Ahmad, J., Stolz, A., Navarro, V. & Hoofnagle, J. H., Sep 1 2017, In : American Journal of Gastroenterology. 112, 9, p. 1382-1388 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Impact of obeticholic acid on the lipoprotein profile in patients with non-alcoholic steatohepatitis

for the NASH CRN, Jan 1 2019, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Importance of Hepatitis C Virus RNA Testing in Patients with Suspected Drug-Induced Liver Injury

Ahmad, J., Reddy, K. R., Tillmann, H. L., Hayashi, P. H., Chalasani, N., Fontana, R. J., Navarro, V. J., Stolz, A., Barnhart, H., Cloherty, G. A. & Hoofnagle, J. H., Sep 15 2019, In : Digestive diseases and sciences. 64, 9, p. 2645-2652 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Improvement in liver histology due to lifestyle modification is independently associated with improved kidney function in patients with non-alcoholic steatohepatitis

Vilar-Gomez, E., Calzadilla-Bertot, L., Friedman, S. L., Gra-Oramas, B., Gonzalez-Fabian, L., Villa-Jimenez, O., Lazo-del Vallin, S., Diago, M., Adams, L. A., Romero-Gomez, M. & Chalasani, N., Jan 1 2017, In : Alimentary Pharmacology and Therapeutics. 45, 2, p. 332-344 13 p.

Research output: Contribution to journalArticle

20 Scopus citations