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  • Naga Chalasani
2017

Features of Autoimmune Hepatitis in Patients With Drug-induced Liver Injury

de Boer, Y. S., Kosinski, A. S., Urban, T. J., Zhao, Z., Long, N., Chalasani, N., Kleiner, D. E. & Hoofnagle, J. H., Jan 1 2017, In : Clinical Gastroenterology and Hepatology. 15, 1, p. 103-112.e2

Research output: Contribution to journalArticle

52 Scopus citations

Genome-Wide Associations Related to Hepatic Histology in Nonalcoholic Fatty Liver Disease in Hispanic Boys

Wattacheril, J., Lavine, J. E., Chalasani, N. P., Guo, X., Kwon, S., Schwimmer, J., Molleston, J. P., Loomba, R., Brunt, E. M., Chen, Y. D. I., Goodarzi, M. O., Taylor, K. D., Yates, K. P., Tonascia, J. & Rotter, J. I., Nov 2017, In : Journal of Pediatrics. 190, p. 100-107.e2

Research output: Contribution to journalArticle

11 Scopus citations

Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease

Ji, S. G., Juran, B. D., Mucha, S., Folseraas, T., Jostins, L., Melum, E., Kumasaka, N., Atkinson, E. J., Schlicht, E. M., Liu, J. Z., Shah, T., Gutierrez-Achury, J., Boberg, K. M., Bergquist, A., Vermeire, S., Eksteen, B., Durie, P. R., Farkkila, M., Müller, T., Schramm, C. & 50 others, Sterneck, M., Weismüller, T. J., Gotthardt, D. N., Ellinghaus, D., Braun, F., Teufel, A., Laudes, M., Lieb, W., Jacobs, G., Beuers, U., Weersma, R. K., Wijmenga, C., Marschall, H. U., Milkiewicz, P., Pares, A., Kontula, K., Chazouillères, O., Invernizzi, P., Goode, E., Spiess, K., Moore, C., Sambrook, J., Ouwehand, W. H., Roberts, D. J., Danesh, J., Floreani, A., Gulamhusein, A. F., Eaton, J. E., Schreiber, S., Coltescu, C., Bowlus, C. L., Luketic, V. A., Odin, J. A., Chopra, K. B., Kowdley, K. V., Chalasani, N., Manns, M. P., Srivastava, B., Mells, G., Sandford, R. N., Alexander, G., Gaffney, D. J., Chapman, R. W., Hirschfield, G. M., De Andrade, M., Rushbrook, S. M., Franke, A., Karlsen, T. H., Lazaridis, K. N. & Anderson, C. A., Jan 31 2017, In : Nature genetics. 49, 2, p. 269-273 5 p.

Research output: Contribution to journalArticle

60 Scopus citations

Identification and Characterization of Fenofibrate-Induced Liver Injury

Ahmad, J., Odin, J. A., Hayashi, P. H., Chalasani, N., Fontana, R. J., Barnhart, H., Cirulli, E. T., Kleiner, D. E. & Hoofnagle, J. H., Dec 1 2017, In : Digestive diseases and sciences. 62, 12, p. 3596-3604 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Idiosyncratic Drug Induced Liver Injury in African-Americans is Associated with Greater Morbidity and Mortality Compared to Caucasians

Chalasani, N., Reddy, K. R. K., Fontana, R. J., Barnhart, H., Gu, J., Hayashi, P. H., Ahmad, J., Stolz, A., Navarro, V. & Hoofnagle, J. H., Sep 1 2017, In : American Journal of Gastroenterology. 112, 9, p. 1382-1388 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Improvement in liver histology due to lifestyle modification is independently associated with improved kidney function in patients with non-alcoholic steatohepatitis

Vilar-Gomez, E., Calzadilla-Bertot, L., Friedman, S. L., Gra-Oramas, B., Gonzalez-Fabian, L., Villa-Jimenez, O., Lazo-del Vallin, S., Diago, M., Adams, L. A., Romero-Gomez, M. & Chalasani, N., Jan 1 2017, In : Alimentary Pharmacology and Therapeutics. 45, 2, p. 332-344 13 p.

Research output: Contribution to journalArticle

20 Scopus citations

In Memoriam—Lawrence Lumeng, MD: Researcher, Clinician, Leader, Mentor, Family Man, and Friend

Chalasani, N., Crabb, D. & Rex, D., Oct 1 2017, In : Gastroenterology. 153, 4, p. 873-874 2 p.

Research output: Contribution to journalEditorial

Lipopolysaccharide downregulates macrophage-derived IL-22 to modulate alcohol-induced hepatocyte cell death

Liu, Y., Verma, V. K., Malhi, H., Gores, G. J., Kamath, P. S., Sanyal, A., Chalasani, N., Gao, B. & Shah, V. H., Sep 5 2017, In : American Journal of Physiology - Cell Physiology. 313, 3, p. C305-C313

Research output: Contribution to journalArticle

6 Scopus citations

Low and High Birth Weights Are Risk Factors for Nonalcoholic Fatty Liver Disease in Children

Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN), Aug 1 2017, In : Journal of Pediatrics. 187, p. 141-146.e1

Research output: Contribution to journalArticle

26 Scopus citations

Minocycline hepatotoxicity: Clinical characterization and identification of HLA-B∗35:02 as a risk factor

Drug-Induced Liver Injury Network (DILIN), Pharmacogenetics of Drug-Induced Liver Injury group (DILIGEN) & International Serious Adverse Events Consortium (iSAEC), Jul 2017, In : Journal of Hepatology. 67, 1, p. 137-144 8 p.

Research output: Contribution to journalArticle

46 Scopus citations

Molecular mechanisms of nonalcoholic fatty liver disease: Potential role for 12-lipoxygenase

Samala, N., Tersey, S. A., Chalasani, N., Anderson, R. M. & Mirmira, R. G., Nov 2017, In : Journal of Diabetes and its Complications. 31, 11, p. 1630-1637 8 p.

Research output: Contribution to journalReview article

8 Scopus citations
17 Scopus citations

Patient Sex, Reproductive Status, and Synthetic Hormone Use Associate With Histologic Severity of Nonalcoholic Steatohepatitis

Yang, J. D., Abdelmalek, M. F., Guy, C. D., Gill, R. M., Lavine, J. E., Yates, K., Klair, J., Terrault, N. A., Clark, J. M., Unalp-Arida, A., Diehl, A. M., Suzuki, A., Dasarathy, S., Dasarathy, J., Hawkins, C., McCullough, A. J., Pagadala, M., Pai, R., Sargent, R., Bashir, M. & 80 others, Buie, S., Kigongo, C., Pan, Y. P., Piercy, D., Chalasani, N., Cummings, O. W., Gawrieh, S., Ghabril, M., Marri, S., Ragozzino, L., Sandrasegaran, K., Vuppalanchi, R., King, D., Osmack, P., Siegner, J., Stewart, S., Neuschwander-Tetri, B. A., Torretta, S., Ang, B., Behling, C., Bhatt, A., Loomba, R., Middleton, M., Patton, H., Sirlin, C., Aouizerat, B., Bass, N. M., Brandman, D., Ferrell, L. D., Hameed, B., Ramos, C., Ungermann, A., Atla, P., Croft, B., Garcia, R., Garcia, S., Sheikh, M., Singh, M., Boyett, S., Carucci, L., Contos, M. J., Kraft, K., Luketic, V. A. C., Puri, P., Sanyal, A. J., Schlosser, J., Siddiqui, M. S., Wolford, B., Ackermann, S., Cooney, S., Coy, D., Gelinas, K., Kowdley, K. V., Lee, M., Pierce, T., Mooney, J., Nelson, J. E., Shaw, C., Siddique, A., Wang, C., Brunt, E. M., Fowler, K., Kleiner, D. E., Grave, G. D., Doo, E. C., Hoofnagle, J. H., Robuck, P. R., Sherker, A., Belt, P., Donithan, M., Hallinan, E., Isaacson, M., May, K. P., Miriel, L., Sternberg, A., Tonascia, J., Ünalp-Arida, A., Van Natta, M., Vaughn, I. & Wilson, L., Jan 1 2017, In : Clinical Gastroenterology and Hepatology. 15, 1, p. 127-131.e2

Research output: Contribution to journalArticle

17 Scopus citations

Perilipin Staining Distinguishes Between Steatosis and Nonalcoholic Steatohepatitis in Adults and Children

Carr, R. M., Dhir, R., Mahadev, K., Comerford, M., Chalasani, N. & Ahima, R. S., Jan 1 2017, In : Clinical Gastroenterology and Hepatology. 15, 1, p. 145-147 3 p.

Research output: Contribution to journalShort survey

7 Scopus citations

Profiles of miRNAs in serum in severe acute drug induced liver injury and their prognostic significance

Russo, M. W., Steuerwald, N., Norton, H. J., Anderson, W. E., Foureau, D., Chalasani, N., Fontana, R. J., Watkins, P. B., Serrano, J. & Bonkovsky, H. L., May 1 2017, In : Liver International. 37, 5, p. 757-764 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Risk factors for hepatocellular carcinoma in cirrhosis due to nonalcoholic fatty liver disease: A multicenter, case-control study

Corey, K. E., Gawrieh, S., deLemos, A. S., Zheng, H., Scanga, A. E., Haglund, J. W., Sanchez, J., Danford, C. J., Comerford, M., Bossi, K., Munir, S., Chalasani, N. & Wattacheril, J., 2017, In : World Journal of Hepatology. 9, 7, p. 385-390 6 p.

Research output: Contribution to journalArticle

6 Scopus citations
2 Scopus citations

The Authors' Response

Ghabril, M. & Chalasani, N., Aug 1 2017, In : Transplantation. 101, 8, p. e282-e283

Research output: Contribution to journalLetter

1 Scopus citations

The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases

Chalasani, N., Younossi, Z., Lavine, J. E., Charlton, M., Cusi, K., Rinella, M., Harrison, S. A., Brunt, E. M. & Sanyal, A. J., 2017, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

882 Scopus citations

Transcriptional regulation of PNPLA3 and its impact on susceptibility to nonalcoholic fatty liver Disease (NAFLD) in humans

FLIP Investigators & FLPGP Investigators, Jan 1 2017, In : Aging. 9, 1, p. 26-40 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

Treatment with LY2409021, a glucagon receptor antagonist, increases liver fat in patients with type 2 diabetes

Guzman, C. B., Zhang, X. M., Liu, R., Regev, A., Shankar, S., Garhyan, P., Pillai, S. G., Kazda, C., Chalasani, N. & Hardy, T. A., 2017, (Accepted/In press) In : Diabetes, Obesity and Metabolism.

Research output: Contribution to journalArticle

41 Scopus citations

Effects of Age, Sex, Body Weight, and Quantity of Alcohol Consumption on Occurrence and Severity of Alcoholic Hepatitis

Translational Research and Evolving Alcoholic Hepatitis Treatment Consortium & Translational Research and Evolving Alcoholic Hepatitis Treatment Consortium, Dec 1 2016, In : Clinical Gastroenterology and Hepatology. 14, 12, p. 1831-1838.e3

Research output: Contribution to journalArticle

19 Scopus citations

Febuxostat-induced acute liver injury

Bohm, M., Vuppalanchi, R., Chalasani, N., Fontana, R. J., Watkins, P. B., Bonkovsky, H. L., Davern, T., Serrano, J. & Rochon, J., Mar 1 2016, In : Hepatology. 63, 3, p. 1047-1049 3 p.

Research output: Contribution to journalArticle

11 Scopus citations

Increased parenchymal damage and steatohepatitis in Caucasian non-alcoholic fatty liver disease patients with common IL1B and IL6 polymorphisms

the NASH Clinical Research Network, Dec 1 2016, In : Alimentary Pharmacology and Therapeutics. 44, 11-12, p. 1253-1264 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Nodular regenerative hyperplasia after treatment with trastuzumab emtansine

Force, J., Saxena, R., Schneider, B., Storniolo, A. M., Sledge, G. W., Chalasani, N. & Vuppalanchi, R., Jan 20 2016, In : Journal of Clinical Oncology. 34, 3, p. e9-e12

Research output: Contribution to journalArticle

14 Scopus citations

Nonalcoholic Fatty Liver Disease in Latinos

Saab, S., Manne, V., Nieto, J., Schwimmer, J. B. & Chalasani, N. P., Jan 1 2016, In : Clinical Gastroenterology and Hepatology. 14, 1, p. 5-12 8 p.

Research output: Contribution to journalReview article

33 Scopus citations

Not routine screening, but vigilance for chronic liver disease in patients with type 2 diabetes

Wong, V. W. S. & Chalasani, N., 2016, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

14 Scopus citations
32 Scopus citations
47 Scopus citations

Randomised clinical study: GR-MD-02, a galectin-3 inhibitor, vs. placebo in patients having non-alcoholic steatohepatitis with advanced fibrosis

Harrison, S. A., Marri, S. R., Chalasani, N., Kohli, R., Aronstein, W., Thompson, G. A., Irish, W., Miles, M. V., Xanthakos, S. A., Lawitz, E., Noureddin, M., Schiano, T. D., Siddiqui, M., Sanyal, A., Neuschwander-Tetri, B. A. & Traber, P. G., Dec 1 2016, In : Alimentary Pharmacology and Therapeutics. 44, 11-12, p. 1183-1198 16 p.

Research output: Contribution to journalArticle

52 Scopus citations

Reply

De Boer, Y. S., Kosinski, A. S., Urban, T. J., Zhao, Z., Long, N., Chalasani, N., Kleiner, D. E. & Hoofnagle, J. H., Dec 1 2016, In : Clinical Gastroenterology and Hepatology. 14, 12, p. 1845-1846 2 p.

Research output: Contribution to journalLetter

1 Scopus citations
1 Scopus citations

Standard Definitions and Common Data Elements for Clinical Trials in Patients with Alcoholic Hepatitis: Recommendation from the NIAAA Alcoholic Hepatitis Consortia

Crabb, D. W., Bataller, R., Chalasani, N. P., Kamath, P. S., Lucey, M., Mathurin, P., McClain, C., McCullough, A., Mitchell, M. C., Morgan, T. R., Nagy, L., Radaeva, S., Sanyal, A., Shah, V. & Szabo, G., Apr 1 2016, In : Gastroenterology. 150, 4, p. 785-790 6 p.

Research output: Contribution to journalEditorial

108 Scopus citations