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  • Howard Edenberg
2020

A Family-Based Genome Wide Association Study of Externalizing Behaviors

Barr, P. B., Salvatore, J. E., Wetherill, L., Anokhin, A., Chan, G., Edenberg, H. J., Kuperman, S., Meyers, J., Nurnberger, J., Porjesz, B., Schuckit, M. & Dick, D. M., May 1 2020, In : Behavior Genetics. 50, 3, p. 175-183 9 p.

Research output: Contribution to journalArticle

A genome-wide association study of interhemispheric theta EEG coherence: implications for neural connectivity and alcohol use behavior

Meyers, J. L., Zhang, J., Chorlian, D. B., Pandey, A. K., Kamarajan, C., Wang, J. C., Wetherill, L., Lai, D., Chao, M., Chan, G., Kinreich, S., Kapoor, M., Bertelsen, S., McClintick, J., Bauer, L., Hesselbrock, V., Kuperman, S., Kramer, J., Salvatore, J. E., Dick, D. M. & 5 others, Agrawal, A., Foroud, T., Edenberg, H. J., Goate, A. & Porjesz, B., Jan 1 2020, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Characterization of Service Use for Alcohol Problems Across Generations and Sex in Adults With Alcohol Use Disorder

Bourdon, J. L., Tillman, R., Francis, M. W., Dick, D. M., Stephenson, M., Kamarajan, C., Edenberg, H. J., Kramer, J., Kuperman, S., Bucholz, K. K. & McCutcheon, V. V., Mar 1 2020, In : Alcoholism: Clinical and Experimental Research. 44, 3, p. 746-757 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Density and Dichotomous Family History Measures of Alcohol Use Disorder as Predictors of Behavioral and Neural Phenotypes: A Comparative Study Across Gender and Race/Ethnicity

Pandey, G., Seay, M. J., Meyers, J. L., Chorlian, D. B., Pandey, A. K., Kamarajan, C., Ehrenberg, M., Pitti, D., Kinreich, S., Subbie-Saenz de Viteri, S., Acion, L., Anokhin, A., Bauer, L., Chan, G., Edenberg, H., Hesselbrock, V., Kuperman, S., McCutcheon, V. V., Bucholz, K. K., Schuckit, M. & 1 others, Porjesz, B., Mar 1 2020, In : Alcoholism: Clinical and Experimental Research. 44, 3, p. 697-710 14 p.

Research output: Contribution to journalArticle

Effects of chronic intermittent ethanol exposure and withdrawal on neuroblastoma cell transcriptome

McClintick, J. N., Thapa, K., Liu, Y., Xuei, X. & Edenberg, H. J., Jun 2020, In : Alcohol. 85, p. 119-126 8 p.

Research output: Contribution to journalArticle

Embryonic ethanol exposure alters expression of sox2 and other early transcripts in zebrafish, producing gastrulation defects

Sarmah, S., Srivastava, R., McClintick, J. N., Janga, S. C., Edenberg, H. J. & Marrs, J. A., Dec 1 2020, In : Scientific reports. 10, 1, 3951.

Research output: Contribution to journalArticle

Open Access

Genome-wide association studies of the self-rating of effects of ethanol (SRE)

Lai, D., Wetherill, L., Kapoor, M., Johnson, E. C., Schwandt, M., Ramchandani, V. A., Goldman, D., Joslyn, G., Rao, X., Liu, Y., Farris, S., Mayfield, R. D., Dick, D., Hesselbrock, V., Kramer, J., McCutcheon, V. V., Nurnberger, J., Tischfield, J., Goate, A., Edenberg, H. J. & 4 others, Porjesz, B., Agrawal, A., Foroud, T. & Schuckit, M., Mar 1 2020, In : Addiction Biology. 25, 2, e12800.

Research output: Contribution to journalArticle

Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium

on behalf of the Psychiatric Genomics Consortium Substance Use Disorders Workgroup, Jan 1 2020, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Polygenic contributions to alcohol use and alcohol use disorders across population-based and clinically ascertained samples

Johnson, E. C., Sanchez-Roige, S., Acion, L., Adams, M. J., Bucholz, K. K., Chan, G., Chao, M. J., Chorlian, D. B., Dick, D. M., Edenberg, H. J., Foroud, T., Hayward, C., Heron, J., Hesselbrock, V., Hickman, M., Kendler, K. S., Kinreich, S., Kramer, J., Kuo, S. I. C., Kuperman, S. & 13 others, Lai, D., McIntosh, A. M., Meyers, J. L., Plawecki, M. H., Porjesz, B., Porteous, D., Schuckit, M. A., Su, J., Zang, Y., Palmer, A. A., Agrawal, A., Clarke, T. K. & Edwards, A. C., Jan 1 2020, (Accepted/In press) In : Psychological Medicine.

Research output: Contribution to journalArticle

Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies

Munn-Chernoff, M. A., Johnson, E. C., Chou, Y. L., Coleman, J. R. I., Thornton, L. M., Walters, R. K., Yilmaz, Z., Baker, J. H., Hübel, C., Gordon, S., Medland, S. E., Watson, H. J., Gaspar, H. A., Bryois, J., Hinney, A., Leppä, V. M., Mattheisen, M., Ripke, S., Yao, S., Giusti-Rodríguez, P. & 332 others, Hanscombe, K. B., Adan, R. A. H., Alfredsson, L., Ando, T., Andreassen, O. A., Berrettini, W. H., Boehm, I., Boni, C., Boraska Perica, V., Buehren, K., Burghardt, R., Cassina, M., Cichon, S., Clementi, M., Cone, R. D., Courtet, P., Crow, S., Crowley, J. J., Danner, U. N., Davis, O. S. P., de Zwaan, M., Dedoussis, G., Degortes, D., DeSocio, J. E., Dick, D. M., Dikeos, D., Dina, C., Dmitrzak-Weglarz, M., Docampo, E., Duncan, L. E., Egberts, K., Ehrlich, S., Escaramís, G., Esko, T., Estivill, X., Farmer, A., Favaro, A., Fernández-Aranda, F., Fichter, M. M., Fischer, K., Föcker, M., Foretova, L., Forstner, A. J., Forzan, M., Franklin, C. S., Gallinger, S., Giegling, I., Giuranna, J., Gonidakis, F., Gorwood, P., Gratacos Mayora, M., Guillaume, S., Guo, Y., Hakonarson, H., Hatzikotoulas, K., Hauser, J., Hebebrand, J., Helder, S. G., Herms, S., Herpertz-Dahlmann, B., Herzog, W., Huckins, L. M., Hudson, J. I., Imgart, H., Inoko, H., Janout, V., Jiménez-Murcia, S., Julià, A., Kalsi, G., Kaminská, D., Karhunen, L., Karwautz, A., Kas, M. J. H., Kennedy, J. L., Keski-Rahkonen, A., Kiezebrink, K., Kim, Y. R., Klump, K. L., Knudsen, G. P. S., La Via, M. C., Le Hellard, S., Levitan, R. D., Li, D., Lilenfeld, L., Lin, B. D., Lissowska, J., Luykx, J., Magistretti, P. J., Maj, M., Mannik, K., Marsal, S., Marshall, C. R., Mattingsdal, M., McDevitt, S., McGuffin, P., Metspalu, A., Meulenbelt, I., Micali, N., Mitchell, K., Monteleone, A. M., Monteleone, P., Nacmias, B., Navratilova, M., Ntalla, I., O'Toole, J. K., Ophoff, R. A., Padyukov, L., Palotie, A., Pantel, J., Papezova, H., Pinto, D., Rabionet, R., Raevuori, A., Ramoz, N., Reichborn-Kjennerud, T., Ricca, V., Ripatti, S., Ritschel, F., Roberts, M., Rotondo, A., Rujescu, D., Rybakowski, F., Santonastaso, P., Scherag, A., Scherer, S. W., Schmidt, U., Schork, N. J., Schosser, A., Seitz, J., Slachtova, L., Slagboom, P. E., Slof-Op't Landt, M. C. T., Slopien, A., Sorbi, S., Świątkowska, B., Szatkiewicz, J. P., Tachmazidou, I., Tenconi, E., Tortorella, A., Tozzi, F., Treasure, J., Tsitsika, A., Tyszkiewicz-Nwafor, M., Tziouvas, K., van Elburg, A. A., van Furth, E. F., Wagner, G., Walton, E., Widen, E., Zeggini, E., Zerwas, S., Zipfel, S., Bergen, A. W., Boden, J. M., Brandt, H., Crawford, S., Halmi, K. A., Horwood, L. J., Johnson, C., Kaplan, A. S., Kaye, W. H., Mitchell, J., Olsen, C. M., Pearson, J. F., Pedersen, N. L., Strober, M., Werge, T., Whiteman, D. C., Woodside, D. B., Grove, J., Henders, A. K., Larsen, J. T., Parker, R., Petersen, L. V., Jordan, J., Kennedy, M. A., Birgegård, A., Lichtenstein, P., Norring, C., Landén, M., Mortensen, P. B., Polimanti, R., McClintick, J. N., Adkins, A. E., Aliev, F., Bacanu, S. A., Batzler, A., Bertelsen, S., Biernacka, J. M., Bigdeli, T. B., Chen, L. S., Clarke, T. K., Degenhardt, F., Docherty, A. R., Edwards, A. C., Foo, J. C., Fox, L., Frank, J., Hack, L. M., Hartmann, A. M., Hartz, S. M., Heilmann-Heimbach, S., Hodgkinson, C., Hoffmann, P., Hottenga, J. J., Konte, B., Lahti, J., Lahti-Pulkkinen, M., Lai, D., Ligthart, L., Loukola, A., Maher, B. S., Mbarek, H., McIntosh, A. M., McQueen, M. B., Meyers, J. L., Milaneschi, Y., Palviainen, T., Peterson, R. E., Ryu, E., Saccone, N. L., Salvatore, J. E., Sanchez-Roige, S., Schwandt, M., Sherva, R., Streit, F., Strohmaier, J., Thomas, N., Wang, J. C., Webb, B. T., Wedow, R., Wetherill, L., Wills, A. G., Zhou, H., Boardman, J. D., Chen, D., Choi, D. S., Copeland, W. E., Culverhouse, R. C., Dahmen, N., Degenhardt, L., Domingue, B. W., Frye, M. A., Gäbel, W., Hayward, C., Ising, M., Keyes, M., Kiefer, F., Koller, G., Kramer, J., Kuperman, S., Lucae, S., Lynskey, M. T., Maier, W., Mann, K., Männistö, S., Müller-Myhsok, B., Murray, A. D., Nurnberger, J. I., Preuss, U., Räikkönen, K., Reynolds, M. D., Ridinger, M., Scherbaum, N., Schuckit, M. A., Soyka, M., Treutlein, J., Witt, S. H., Wodarz, N., Zill, P., Adkins, D. E., Boomsma, D. I., Bierut, L. J., Brown, S. A., Bucholz, K. K., Costello, E. J., de Wit, H., Diazgranados, N., Eriksson, J. G., Farrer, L. A., Foroud, T., Gillespie, N. A., Goate, A. M., Goldman, D., Grucza, R. A., Hancock, D. B., Harris, K. M., Hesselbrock, V., Hewitt, J. K., Hopfer, C. J., Iacono, W. G., Johnson, E. O., Karpyak, V. M., Kendler, K. S., Kranzler, H. R., Krauter, K., Lind, P. A., McGue, M., MacKillop, J., Madden, P. A. F., Maes, H. H., Magnusson, P. K. E., Nelson, E. C., Nöthen, M. M., Palmer, A. A., Penninx, B. W. J. H., Porjesz, B., Rice, J. P., Rietschel, M., Riley, B. P., Rose, R. J., Shen, P. H., Silberg, J., Stallings, M. C., Tarter, R. E., Vanyukov, M. M., Vrieze, S., Wall, T. L., Whitfield, J. B., Zhao, H., Neale, B. M., Wade, T. D., Heath, A. C., Montgomery, G. W., Martin, N. G., Sullivan, P. F., Kaprio, J., Breen, G., Gelernter, J., Edenberg, H. J., Bulik, C. M. & Agrawal, A., Jan 1 2020, (Accepted/In press) In : Addiction Biology. e12880.

Research output: Contribution to journalArticle

Sibling comparisons elucidate the associations between educational attainment polygenic scores and alcohol, nicotine and cannabis

Salvatore, J. E., Barr, P. B., Stephenson, M., Aliev, F., Kuo, S. I. C., Su, J., Agrawal, A., Almasy, L., Bierut, L., Bucholz, K., Chan, G., Edenberg, H. J., Johnson, E. C., McCutcheon, V. V., Meyers, J. L., Schuckit, M., Tischfield, J., Wetherill, L. & Dick, D. M., Feb 1 2020, In : Addiction. 115, 2, p. 337-346 10 p.

Research output: Contribution to journalArticle

The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls

Bipolar Disorder Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jan 1 2020, (Accepted/In press) In : Biological psychiatry.

Research output: Contribution to journalArticle

3 Scopus citations

The Moderate Alcohol and Cardiovascular Health Trial (MACH15): Design and methods for a randomized trial of moderate alcohol consumption and cardiometabolic risk

Spiegelman, D., Lovato, L. C., Khudyakov, P., Wilkens, T. L., Adebamowo, C. A., Adebamowo, S. N., Appel, L. J., Beulens, J. W. J., Coughlin, J. W., Dragsted, L. O., Edenberg, H. J., Eriksen, J. N., Estruch, R., Grobbee, D. E., Gulayin, P. E., Irazola, V., Krystal, J. H., Lazo, M., Murray, M. M., Rimm, E. B. & 3 others, Schrieks, I. C., Williamson, J. D. & Mukamal, K. J., Jan 1 2020, (Accepted/In press) In : European Journal of Preventive Cardiology.

Research output: Contribution to journalArticle

1 Scopus citations
2018

A 22-Year Follow-Up (Range 16 to 23) of Original Subjects with Baseline Alcohol Use Disorders from the Collaborative Study on Genetics of Alcoholism

Schuckit, M. A., Smith, T. L., Danko, G., Kramer, J., Bucholz, K. K., McCutcheon, V., Chan, G., Kuperman, S., Hesselbrock, V., Dick, D. M., Hesselbrock, M., Porjesz, B., Edenberg, H. J., Nureberger, J. I., Gregg, M., Schoen, L., Kawamura, M. & Mendoza, L. A., Sep 2018, In : Alcoholism: Clinical and Experimental Research. 42, 9, p. 1704-1714 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

A Brief Critique of the TATES Procedure

Aliev, F., Salvatore, J. E., Agrawal, A., Almasy, L., Chan, G., Edenberg, H. J., Hesselbrock, V., Kuperman, S., Meyers, J. & Dick, D. M., Mar 1 2018, In : Behavior Genetics. 48, 2, p. 155-167 13 p.

Research output: Contribution to journalArticle

A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework

Schizophrenia and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium, Jun 25 2018, In : BMC genomics. 19, 1, 494.

Research output: Contribution to journalArticle

3 Scopus citations

Alcohol Dehydrogenases

Edenberg, H. J. & Bosron, W. F., Jan 1 2018, Biotransformation. Elsevier Inc., Vol. 10-15. p. 126-145 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Alcohol Dehydrogenases, Aldehyde Dehydrogenases, and Alcohol Use Disorders: A Critical Review

Edenberg, H. J. & McClintick, J. N., Dec 2018, In : Alcoholism: Clinical and Experimental Research. 42, 12, p. 2281-2297 17 p.

Research output: Contribution to journalReview article

22 Scopus citations

Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium, Dec 1 2018, In : Communications Biology. 1, 1, 163.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Associations of parental alcohol use disorders and parental separation with offspring initiation of alcohol, cigarette and cannabis use and sexual debut in high-risk families

McCutcheon, V. V., Agrawal, A., Kuo, S. I. C., Su, J., Dick, D. M., Meyers, J. L., Edenberg, H. J., Nurnberger, J. I., Kramer, J. R., Kuperman, S., Schuckit, M. A., Hesselbrock, V. M., Brooks, A., Porjesz, B. & Bucholz, K. K., Feb 1 2018, In : Addiction. 113, 2, p. 336-345 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

CYP2A6 metabolism in the development of smoking behaviors in young adults

Olfson, E., Bloom, J., Bertelsen, S., Budde, J. P., Breslau, N., Brooks, A., Culverhouse, R., Chan, G., Chen, L. S., Chorlian, D., Dick, D. M., Edenberg, H. J., Hartz, S., Hatsukami, D., Hesselbrock, V. M., Johnson, E. O., Kramer, J. R., Kuperman, S., Meyers, J. L., Nurnberger, J. & 8 others, Porjesz, B., Saccone, N. L., Schuckit, M. A., Stitzel, J., Tischfield, J. A., Rice, J. P., Goate, A. & Bierut, L. J., Jan 2018, In : Addiction Biology. 23, 1, p. 437-447 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Detecting significant genotype–phenotype association rules in bipolar disorder: market research meets complex genetics

Breuer, R., Mattheisen, M., Frank, J., Krumm, B., Treutlein, J., Kassem, L., Strohmaier, J., Herms, S., Mühleisen, T. W., Degenhardt, F., Cichon, S., Nöthen, M. M., Karypis, G., Kelsoe, J., Greenwood, T., Nievergelt, C., Shilling, P., Shekhtman, T., Edenberg, H., Craig, D. & 32 others, Szelinger, S., Nurnberger, J., Gershon, E., Alliey-Rodriguez, N., Zandi, P., Goes, F., Schork, N., Smith, E., Koller, D., Zhang, P., Badner, J., Berrettini, W., Bloss, C., Byerley, W., Coryell, W., Foroud, T., Guo, Y., Hipolito, M., Keating, B., Lawson, W., Liu, C., Mahon, P., McInnis, M., Murray, S., Nwulia, E., Potash, J., Rice, J., Scheftner, W., Zöllner, S., McMahon, F. J., Rietschel, M. & Schulze, T. G., Dec 1 2018, In : International Journal of Bipolar Disorders. 6, 1, 24.

Research output: Contribution to journalArticle

2 Scopus citations

Gene expression changes in the ventral hippocampus and medial prefrontal cortex of adolescent alcohol-preferring (P) rats following binge-like alcohol drinking

McClintick, J. N., McBride, W. J., Bell, R. L., Ding, Z. M., Liu, Y., Xuei, X. & Edenberg, H. J., May 2018, In : Alcohol. 68, p. 37-47 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Genome-wide association study identifies a novel locus for cannabis dependence

Agrawal, A., Chou, Y. L., Carey, C. E., Baranger, D. A. A., Zhang, B., Sherva, R., Wetherill, L., Kapoor, M., Wang, J. C., Bertelsen, S., Anokhin, A. P., Hesselbrock, V., Kramer, J., Lynskey, M. T., Meyers, J. L., Nurnberger, J. I., Rice, J. P., Tischfield, J., Bierut, L. J., Degenhardt, L. & 16 others, Farrer, L. A., Gelernter, J., Hariri, A. R., Heath, A. C., Kranzler, H. R., Madden, P. A. F., Martin, N. G., Montgomery, G. W., Porjesz, B., Wang, T., Whitfield, J. B., Edenberg, H. J., Foroud, T., Goate, A. M., Bogdan, R. & Nelson, E. C., May 1 2018, In : Molecular Psychiatry. 23, 5, p. 1293-1302 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium douglas.ruderfer@vanderbilt.edu, Psychosis Endophenotypes International Consortium & Wellcome Trust Case-Control Consortium, Jun 14 2018, In : Cell. 173, 7, p. 1705-1715.e16

Research output: Contribution to journalArticle

121 Scopus citations

Influence of Parental Alcohol Dependence Symptoms and Parenting on Adolescent Risky Drinking and Conduct Problems: A Family Systems Perspective

Su, J., Kuo, S. I. C., Aliev, F., Guy, M. C., Derlan, C. L., Edenberg, H. J., Nurnberger, J. I., Kramer, J. R., Bucholz, K. K., Salvatore, J. E. & Dick, D. M., Sep 2018, In : Alcoholism: Clinical and Experimental Research. 42, 9, p. 1783-1794 12 p.

Research output: Contribution to journalArticle

Psychiatric genomics: An update and an Agenda

Psychiatric Genomics Consortium Coordinating Committee, Jan 1 2018, In : American Journal of Psychiatry. 175, 1, p. 15-27 13 p.

Research output: Contribution to journalArticle

156 Scopus citations

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

23andMe Research Team, Dec 1 2018, In : Nature Neuroscience. 21, 12, p. 1656-1669 14 p.

Research output: Contribution to journalArticle

Open Access
74 Scopus citations

Understanding Mechanisms of Genetic Risk for Adolescent Internalizing and Externalizing Problems: The Mediating Role of Parenting and Personality

Su, J., Kuo, S. I. C., Bucholz, K. K., Edenberg, H. J., Kramer, J. R., Schuckit, M. & Dick, D. M., Aug 1 2018, In : Twin Research and Human Genetics. 21, 4, p. 310-321 12 p.

Research output: Contribution to journalArticle

2017

A GABRA2 polymorphism improves a model for prediction of drinking initiation

Kuperman, S., Chan, G., Kramer, J., Wetherill, L., Acion, L., Edenberg, H. J., Foroud, T. M., Nurnberger, J., Agrawal, A., Anokhin, A., Brooks, A., Hesselbrock, V., Hesselbrock, M., Schuckit, M., Tischfield, J. & Liu, X., Sep 2017, In : Alcohol. 63, p. 1-8 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

A genome wide association study of fast beta EEG in families of European ancestry

Meyers, J. L., Zhang, J., Manz, N., Rangaswamy, M., Kamarajan, C., Wetherill, L., Chorlian, D. B., Kang, S. J., Bauer, L., Hesselbrock, V., Kramer, J., Kuperman, S., Nurnberger, J. I., Tischfield, J., Wang, J. C., Edenberg, H. J., Goate, A., Foroud, T. & Porjesz, B., May 1 2017, In : International Journal of Psychophysiology. 115, p. 74-85 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

A KCNJ6 gene polymorphism modulates theta oscillations during reward processing

Kamarajan, C., Pandey, A. K., Chorlian, D. B., Manz, N., Stimus, A. T., Edenberg, H. J., Wetherill, L., Schuckit, M., Wang, J. C., Kuperman, S., Kramer, J., Tischfield, J. A. & Porjesz, B., May 1 2017, In : International Journal of Psychophysiology. 115, p. 13-23 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

An endophenotype approach to the genetics of alcohol dependence: A genome wide association study of fast beta EEG in families of African ancestry

Meyers, J. L., Zhang, J., Wang, J. C., Su, J., Kuo, S. I., Kapoor, M., Wetherill, L., Bertelsen, S., Lai, D., Salvatore, J. E., Kamarajan, C., Chorlian, D., Agrawal, A., Almasy, L., Bauer, L., Bucholz, K. K., Chan, G., Hesselbrock, V., Koganti, L., Kramer, J. & 11 others, Kuperman, S., Manz, N., Pandey, A., Seay, M., Scott, D., Taylor, R. E., Dick, D. M., Edenberg, H. J., Goate, A., Foroud, T. & Porjesz, B., Dec 1 2017, In : Molecular Psychiatry. 22, 12, p. 1767-1775 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Characterizing the roles of long non-coding RNA in rat alcohol preference

Zhou, A., Wang, Y., Liu, Y., Feng, W. & Edenberg, H., Jan 17 2017, Proceedings - 2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016. Institute of Electrical and Electronics Engineers Inc., p. 167-173 7 p. 7822513

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Comparison of Parent, Peer, Psychiatric, and Cannabis Use Influences Across Stages of Offspring Alcohol Involvement: Evidence from the COGA Prospective Study

Bucholz, K. K., McCutcheon, V. V., Agrawal, A., Dick, D. M., Hesselbrock, V. M., Kramer, J. R., Kuperman, S., Nurnberger, J. I., Salvatore, J. E., Schuckit, M. A., Bierut, L. J., Foroud, T. M., Chan, G., Hesselbrock, M., Meyers, J. L., Edenberg, H. J. & Porjesz, B., Feb 1 2017, In : Alcoholism: Clinical and Experimental Research. 41, 2, p. 359-368 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

Familial association of abstinent remission from alcohol use disorder in first-degree relatives of alcohol-dependent treatment-seeking probands

McCutcheon, V. V., Schuckit, M. A., Kramer, J. R., Chan, G., Edenberg, H. J., Smith, T. L., Bender, A. K., Hesselbrock, V., Hesselbrock, M. & Bucholz, K. K., Nov 2017, In : Addiction. 112, 11, p. 1909-1917 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Genetic correlates of the development of theta event related oscillations in adolescents and young adults

Chorlian, D. B., Rangaswamy, M., Manz, N., Meyers, J. L., Kang, S. J., Kamarajan, C., Pandey, A. K., Wang, J. C., Wetherill, L., Edenberg, H. & Porjesz, B., May 1 2017, In : International Journal of Psychophysiology. 115, p. 24-39 16 p.

Research output: Contribution to journalArticle

4 Scopus citations

Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis

PGC ADHD Working Group & PGC Bipolar Disorder Working Group, Nov 1 2017, In : Biological psychiatry. 82, 9, p. 634-641 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms

Collaborative Study of the Genetics of Alcoholism Consortium & the German Study of the Genetics of Addiction Consortium, May 2017, In : Alcoholism: Clinical and Experimental Research. 41, 5, p. 911-928 18 p.

Research output: Contribution to journalArticle

17 Scopus citations

Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia

Schizophrenia Working Group of the Psychiatric Genomics Consortium, Bipolar Disorders Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jun 20 2017, In : Translational psychiatry. 7, 6, p. e1155

Research output: Contribution to journalArticle

43 Scopus citations

Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence

Andersen, A. M., Pietrzak, R. H., Kranzler, H. R., Ma, L., Zhou, H., Liu, X., Kramer, J., Kuperman, S., Edenberg, H. J., Nurnberger, J. I., Rice, J. P., Tischfield, J. A., Goate, A., Foroud, T. M., Meyers, J. L., Porjesz, B., Dick, D. M., Hesselbrock, V., Boerwinkle, E., Southwick, S. M. & 6 others, Krystal, J. H., Weissman, M. M., Levinson, D. F., Potash, J. B., Gelernter, J. & Han, S., Nov 1 2017, In : JAMA psychiatry. 74, 11, p. 1153-1160 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

RareVar: A Framework for Detecting Low-Frequency Single-Nucleotide Variants

Hao, Y., Xuei, X., Li, L., Nakshatri, H., Edenberg, H. J. & Liu, Y., Jul 1 2017, In : Journal of Computational Biology. 24, 7, p. 637-646 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Reciprocal relationships between substance use and disorders and suicidal ideation and suicide attempts in the Collaborative Study of the Genetics of Alcoholism

Agrawal, A., Tillman, R., Grucza, R. A., Nelson, E. C., McCutcheon, V. V., Few, L., Conner, K. R., Lynskey, M. T., Dick, D. M., Edenberg, H. J., Hesselbrock, V. M., Kramer, J. R., Kuperman, S., Nurnberger, J. I., Schuckit, M. A., Porjesz, B. & Bucholz, K. K., Apr 15 2017, In : Journal of Affective Disorders. 213, p. 96-104 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Substance use disorders in adolescent and young adult relatives of probands with bipolar disorder: What drives the increased risk?

Hulvershorn, L. A., King, J., Monahan, P. O., Wilcox, H. C., Mitchell, P. B., Fullerton, J. M., Edenberg, H. J., Roberts, G. M. P., Kamali, M., Glowinski, A. L., Ghaziuddin, N., McInnis, M., Iyer-Eimerbrink, P. A. & Nurnberger, J. I., Oct 2017, In : Comprehensive Psychiatry. 78, p. 130-139 10 p.

Research output: Contribution to journalArticle

1 Scopus citations
12 Scopus citations

Traumatic Stress Interacts With Bipolar Disorder Genetic Risk to Increase Risk for Suicide Attempts

Wilcox, H. C., Fullerton, J. M., Glowinski, A. L., Benke, K., Kamali, M., Hulvershorn, L. A., Stapp, E. K., Edenberg, H. J., Roberts, G. M. P., Ghaziuddin, N., Fisher, C., Brucksch, C., Frankland, A., Toma, C., Shaw, A. D., Kastelic, E., Miller, L., McInnis, M. G., Mitchell, P. B. & Nurnberger, J. I., Dec 2017, In : Journal of the American Academy of Child and Adolescent Psychiatry. 56, 12, p. 1073-1080 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Using Patterns of Genetic Association to Elucidate Shared Genetic Etiologies Across Psychiatric Disorders

Cho, S. B., Aliev, F., Clark, S. L., Adkins, A. E., Edenberg, H. J., Bucholz, K. K., Porjesz, B. & Dick, D. M., Jul 1 2017, In : Behavior Genetics. 47, 4, p. 405-415 11 p.

Research output: Contribution to journalArticle

1 Scopus citations
3 Scopus citations
2016

A genome-wide association study of bipolar disorder with comorbid eating disorder replicates the SOX2-OT region

Bipolar Genome Study (BiGS), Jan 1 2016, In : Journal of Affective Disorders. 189, p. 141-149 9 p., 7712.

Research output: Contribution to journalArticle

24 Scopus citations

Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts

Schwantes-An, T. H., Zhang, J., Chen, L. S., Hartz, S. M., Culverhouse, R. C., Chen, X., Coon, H., Frank, J., Kamens, H. M., Konte, B., Kovanen, L., Latvala, A., Legrand, L. N., Maher, B. S., Melroy, W. E., Nelson, E. C., Reid, M. W., Robinson, J. D., Shen, P. H., Yang, B. Z. & 90 others, Andrews, J. A., Aveyard, P., Beltcheva, O., Brown, S. A., Cannon, D. S., Cichon, S., Corley, R. P., Dahmen, N., Degenhardt, L., Foroud, T., Gaebel, W., Giegling, I., Glatt, S. J., Grucza, R. A., Hardin, J., Hartmann, A. M., Heath, A. C., Herms, S., Hodgkinson, C. A., Hoffmann, P., Hops, H., Huizinga, D., Ising, M., Johnson, E. O., Johnstone, E., Kaneva, R. P., Kendler, K. S., Kiefer, F., Kranzler, H. R., Krauter, K. S., Levran, O., Lucae, S., Lynskey, M. T., Maier, W., Mann, K., Martin, N. G., Mattheisen, M., Montgomery, G. W., Müller-Myhsok, B., Murphy, M. F., Neale, M. C., Nikolov, M. A., Nishita, D., Nöthen, M. M., Nurnberger, J., Partonen, T., Pergadia, M. L., Reynolds, M., Ridinger, M., Rose, R. J., Rouvinen-Lagerström, N., Scherbaum, N., Schmäl, C., Soyka, M., Stallings, M. C., Steffens, M., Treutlein, J., Tsuang, M., Wall, T. L., Wodarz, N., Yuferov, V., Zill, P., Bergen, A. W., Chen, J., Cinciripini, P. M., Edenberg, H. J., Ehringer, M. A., Ferrell, R. E., Gelernter, J., Goldman, D., Hewitt, J. K., Hopfer, C. J., Iacono, W. G., Kaprio, J., Kreek, M. J., Kremensky, I. M., Madden, P. A. F., McGue, M., Munafò, M. R., Philibert, R. A., Rietschel, M., Roy, A., Rujescu, D., Saarikoski, S. T., Swan, G. E., Todorov, A. A., Vanyukov, M. M., Weiss, R. B., Bierut, L. J. & Saccone, N. L., Mar 1 2016, In : Behavior Genetics. 46, 2, p. 151-169 19 p.

Research output: Contribution to journalArticle

51 Scopus citations