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  • Naga Chalasani
2020

Alcohol Rehabilitation Within 30 Days of Hospital Discharge Is Associated With Reduced Readmission, Relapse, and Death in Patients With Alcoholic Hepatitis

Peeraphatdit, T. B., Kamath, P. S., Karpyak, V. M., Davis, B., Desai, V., Liangpunsakul, S., Sanyal, A., Chalasani, N., Shah, V. H. & Simonetto, D. A., Feb 2020, In : Clinical Gastroenterology and Hepatology. 18, 2, p. 477-485.e5

Research output: Contribution to journalArticle

2 Scopus citations

Apolipoprotein B and PNPLA3 Double Heterozygosity in a Father–Son Pair With Advanced Nonalcoholic Fatty Liver Disease

Jansson-Knodell, C. L., Gawrieh, S., McIntyre, A. D., Liang, T., Hegele, R. A. & Chalasani, N., Jan 1 2020, In : Hepatology. 71, 1, p. 383-385 3 p.

Research output: Contribution to journalArticle

Automated quantification and architectural pattern detection of hepatic fibrosis in NAFLD

Gawrieh, S., Sethunath, D., Cummings, O. W., Kleiner, D. E., Vuppalanchi, R., Chalasani, N. & Tuceryan, M., Aug 2020, In : Annals of Diagnostic Pathology. 47, 151518.

Research output: Contribution to journalArticle

Clinical Characteristics and Adverse Impact of Hepatotoxicity due to Immune Checkpoint Inhibitors

Miller, E. D., Abu-Sbeih, H., Styskel, B., Nogueras Gonzalez, G. M., Blechacz, B., Naing, A. & Chalasani, N., Feb 1 2020, In : The American journal of gastroenterology. 115, 2, p. 251-261 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Consensus guidelines: best practices for detection, assessment and management of suspected acute drug-induced liver injury occurring during clinical trials in adults with chronic cholestatic liver disease

Palmer, M., Regev, A., Lindor, K., Avigan, M. I., Dimick-Santos, L., Treem, W., Marcinak, J. F., Lewis, J. H., Anania, F. A., Seekins, D., Shneider, B. L. & Chalasani, N., Jan 1 2020, In : Alimentary Pharmacology and Therapeutics. 51, 1, p. 90-109 20 p.

Research output: Contribution to journalReview article

Open Access

Distinctive Features and Outcomes of Hepatocellular Carcinoma in Patients With Alcohol-Related Liver Disease: A US Multicenter Study

deLemos, A., Patel, M., Gawrieh, S., Burney, H., Dakhoul, L., Miller, E., Scanga, A., Kettler, C., Liu, H., Roche, P., Wattacheril, J. & Chalasani, N., Mar 1 2020, In : Clinical and translational gastroenterology. 11, 3, p. e00139

Research output: Contribution to journalArticle

Open Access

Effects of Belapectin, an Inhibitor of Galectin-3, in Patients With Nonalcoholic Steatohepatitis With Cirrhosis and Portal Hypertension

The Belapectin (GR-MD-02) Study Investigators, Apr 2020, In : Gastroenterology. 158, 5, p. 1334-1345.e5

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
Open Access

Persistent Hyperactivation of Endothelial Cells in Patients with Alcoholic Hepatitis

Xia, Y., Yang, J., Sanyal, A. J., Shah, V. H., Chalasani, N. P., Yu, Q., Zheng, X. & Li, W., May 1 2020, In : Alcoholism: Clinical and Experimental Research. 44, 5, p. 1075-1087 13 p.

Research output: Contribution to journalArticle

Significant Medical Comorbidities Are Associated With Lower Causality Scores in Patients Presenting With Suspected Drug-Induced Liver Injury

Ghabril, M., Gu, J., Yoder, L., Corbito, L., Dakhoul, L., Ringel, A., Beyer, C. D., Vuppalanchi, R., Barnhart, H., Hayashi, P. H. & Chalasani, N., Apr 1 2020, In : Clinical and translational gastroenterology. 11, 4, p. e00141

Research output: Contribution to journalArticle

Open Access

Spontaneous Fluctuations in Liver Biochemistries in Patients with Compensated NASH Cirrhosis: Implications for Drug Hepatotoxicity Monitoring

Shamseddeen, H., Vilar-Gomez, E., Chalasani, N., Myers, R. P., Subramanian, G. M., Shlevin, H. H., Allgood, A. E. & Orman, E. S., Mar 1 2020, In : Drug Safety. 43, 3, p. 281-290 10 p.

Research output: Contribution to journalArticle

14 Scopus citations
2019

Admission plasma uromodulin and the risk of acute kidney injury in hospitalized patients with cirrhosis: a pilot study

Patidar, K. R., Garimella, P. S., Macedo, E., Slaven, J. E., Ghabril, M. S., Weber, R. E., Anderson, M., Orman, E. S., Nephew, L. D., Desai, A. P., Chalasani, N. P. & El-Achkar, T. M., Oct 1 2019, In : American journal of physiology. Gastrointestinal and liver physiology. 317, 4, p. G447-G452

Research output: Contribution to journalArticle

Advice Regarding Alcohol Use by Individuals With Nonalcoholic Fatty Liver Disease: Primum non nocere

Dunn, W. & Chalasani, N., Jan 2019, In : Hepatology. 69, 1, p. 9-11 3 p.

Research output: Contribution to journalEditorial

Alcohol abstinence does not fully reverse abnormalities of mucosal-associated invariant T cells in the blood of patients with alcoholic hepatitis

Li, W., Lin, E. L., Liangpunsakul, S., Lan, J., Chalasani, S., Rane, S., Puri, P., Kamath, P. S., Sanyal, A. J., Shah, V. H., Radaeva, S., Crabb, D. W., Chalasani, N. & Yu, Q., Jun 1 2019, In : Clinical and translational gastroenterology. 10, 6, e-00052.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury

Drug-Induced Liver Injury Network (DILIN) investigators & International DILI consortium (iDILIC), May 2019, In : Gastroenterology. 156, 6, p. 1707-1716.e2

Research output: Contribution to journalArticle

20 Scopus citations

Association of Histologic Disease Activity With Progression of Nonalcoholic Fatty Liver Disease

Nonalcoholic Steatohepatitis Clinical Research Network, Oct 2 2019, In : JAMA Network Open. 2, 10, p. e1912565

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Black Adult Patients With Acute Liver Failure Are Sicker and More Likely to Undergo Liver Transplantation Than White Patients

Nephew, L., Zia, Z., Ghabril, M., Orman, E., Lammert, C. & Chalasani, N., Nov 1 2019, In : Liver Transplantation. 25, 11, p. 1634-1641 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Candidate biomarkers for the diagnosis and prognosis of drug-induced liver injury: An international collaborative effort

Church, R. J., Kullak-Ublick, G. A., Aubrecht, J., Bonkovsky, H. L., Chalasani, N., Fontana, R. J., Goepfert, J. C., Hackman, F., King, N. M. P., Kirby, S., Kirby, P., Marcinak, J., Ormarsdottir, S., Schomaker, S. J., Schuppe-Koistinen, I., Wolenski, F., Arber, N., Merz, M., Sauer, J. M., Andrade, R. J. & 3 others, van Bömmel, F., Poynard, T. & Watkins, P. B., Feb 1 2019, In : Hepatology. 69, 2, p. 760-773 14 p.

Research output: Contribution to journalArticle

45 Scopus citations

Characteristics, aetiologies and trends of hepatocellular carcinoma in patients without cirrhosis: a United States multicentre study

Gawrieh, S., Dakhoul, L., Miller, E., Scanga, A., deLemos, A., Kettler, C., Burney, H., Liu, H., Abu-Sbeih, H., Chalasani, N. & Wattacheril, J., Oct 1 2019, In : Alimentary Pharmacology and Therapeutics. 50, 7, p. 809-821 13 p.

Research output: Contribution to journalArticle

8 Scopus citations

Consensus: guidelines: best practices for detection, assessment and management of suspected acute drug-induced liver injury during clinical trials in patients with nonalcoholic steatohepatitis

Regev, A., Palmer, M., Avigan, M. I., Dimick-Santos, L., Treem, W. R., Marcinak, J. F., Seekins, D., Krishna, G., Anania, F. A., Freston, J. W., Lewis, J. H., Sanyal, A. J. & Chalasani, N., Mar 2019, In : Alimentary Pharmacology and Therapeutics. 49, 6, p. 702-713 12 p.

Research output: Contribution to journalReview article

4 Scopus citations

Correction: Cytokine profiles in acute liver injury-Results from the US Drug-Induced Liver Injury Network (DILIN) and the Acute Liver Failure Study Group (PLoS ONE (2018) 13:10 (e0206389) DOI: 10.1371/journal.pone.0206389)

US Drug-Induced Liver Injury Network and the Acute Liver Failure Study Group, Feb 2019, In : PloS one. 14, 2, e0212394.

Research output: Contribution to journalComment/debate

Open Access

Development and Validation of a Model Consisting of Comorbidity Burden to Calculate Risk of Death Within 6 Months for Patients With Suspected Drug-Induced Liver Injury

Ghabril, M., Gu, J., Yoder, L., Corbito, L., Ringel, A., Beyer, C. D., Vuppalanchi, R., Barnhart, H., Hayashi, P. H. & Chalasani, N., Nov 2019, In : Gastroenterology. 157, 5, p. 1245-1252.e3

Research output: Contribution to journalArticle

Development and Validation of a Model to Predict Acute Kidney Injury in Hospitalized Patients With Cirrhosis

Patidar, K. R., Xu, C., Shamseddeen, H., Cheng, Y. W., Ghabril, M. S., Mukthinuthalapati, V. V. P. K., Fricker, Z. P., Akinyeye, S., Nephew, L. D., Desai, A. P., Anderson, M., El-Achkar, T. M., Chalasani, N. P. & Orman, E. S., Sep 1 2019, In : Clinical and translational gastroenterology. 10, 9, p. e00075

Research output: Contribution to journalArticle

Open Access

Diagnostic Accuracy of Noninvasive Fibrosis Models to Detect Change in Fibrosis Stage

NASH Clinical Research Network, Aug 2019, In : Clinical Gastroenterology and Hepatology. 17, 9, p. 1877-1885.e5

Research output: Contribution to journalArticle

17 Scopus citations

Drug-induced liver injury

Chalasani, N. & Crabb, D., Jan 1 2019, In : Gastroenterology and Hepatology. 15, 1, p. 35-37 3 p.

Research output: Contribution to journalComment/debate

Drug-induced liver injury

Andrade, R. J., Chalasani, N., Björnsson, E. S., Suzuki, A., Kullak-Ublick, G. A., Watkins, P. B., Devarbhavi, H., Merz, M., Lucena, M. I., Kaplowitz, N. & Aithal, G. P., Dec 1 2019, In : Nature Reviews Disease Primers. 5, 1, 58.

Research output: Contribution to journalArticle

4 Scopus citations
3 Scopus citations

Early predictors of outcomes of hospitalization for cirrhosis and assessment of the impact of race and ethnicity at safety-net hospitals

Mukthinuthalapati, V. V. P. K., Akinyeye, S., Fricker, Z. P., Syed, M., Orman, E. S., Nephew, L., Vilar-Gomez, E., Slaven, J., Chalasani, N., Balakrishnan, M., Long, M. T., Attar, B. M. & Ghabril, M., Mar 1 2019, In : PLoS ONE. 14, 3, e0211811.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Expanding the Donor Pool With the Use of Extended Criteria Donation After Circulatory Death Livers

Mihaylov, P., Mangus, R., Ekser, B., Cabrales, A., Timsina, L., Fridell, J., Lacerda, M., Ghabril, M., Nephew, L., Chalasani, N. & Kubal, C. A., Jan 1 2019, In : Liver Transplantation.

Research output: Contribution to journalArticle

9 Scopus citations

Factors Associated With Histologic Response in Adult Patients With Nonalcoholic Steatohepatitis

Loomba, R., Sanyal, A. J., Kowdley, K. V., Terrault, N., Chalasani, N. P., Abdelmalek, M. F., McCullough, A. J., Shringarpure, R., Ferguson, B., Lee, L., Chen, J., Liberman, A., Shapiro, D. & Neuschwander-Tetri, B. A., Jan 2019, In : Gastroenterology. 156, 1, p. 88-95.e5

Research output: Contribution to journalArticle

6 Scopus citations

Haptoglobin 2 Allele is Associated with Histologic Response to Vitamin E in Subjects with Nonalcoholic Steatohepatitis

Banini, B. A., Cazanave, S. C., Yates, K. P., Asgharpour, A., Vincent, R., Mirshahi, F., Le, P., Contos, M. J., Tonascia, J., Chalasani, N. P., Kowdley, K. V., McCullough, A. J., Behling, C. A., Schwimmer, J. B., Lavine, J. E. & Sanyal, A. J., Nov 1 2019, In : Journal of Clinical Gastroenterology. 53, 10, p. 750-758 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Histologic Findings of Advanced Fibrosis and Cirrhosis in Patients With Nonalcoholic Fatty Liver Disease Who Have Normal Aminotransferase Levels

and the NASH Clinical Research Network, Oct 1 2019, In : The American journal of gastroenterology. 114, 10, p. 1626-1635 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Impact of obeticholic acid on the lipoprotein profile in patients with non-alcoholic steatohepatitis

for the NASH CRN, Jan 1 2019, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Importance of Hepatitis C Virus RNA Testing in Patients with Suspected Drug-Induced Liver Injury

Ahmad, J., Reddy, K. R., Tillmann, H. L., Hayashi, P. H., Chalasani, N., Fontana, R. J., Navarro, V. J., Stolz, A., Barnhart, H., Cloherty, G. A. & Hoofnagle, J. H., Sep 15 2019, In : Digestive diseases and sciences. 64, 9, p. 2645-2652 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Increasing economic burden in hospitalized patients with cirrhosis: Analysis of a national database

Desai, A. P., Mohan, P., Nokes, B., Sheth, D., Knapp, S., Boustani, M., Chalasani, N., Fallon, M. B. & Calhoun, E. A., Jan 1 2019, In : Clinical and translational gastroenterology. 10, 7, e-00062.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Is Fasting Necessary for Individuals with Nonalcoholic Fatty Liver Disease to Undergo Vibration-Controlled Transient Elastography?

Vuppalanchi, R., Weber, R., Russell, S., Gawrieh, S., Samala, N., Slaven, J. E., Harden, L. & Chalasani, N., Jun 1 2019, In : American Journal of Gastroenterology. 114, 6, p. 995-997 3 p.

Research output: Contribution to journalArticle

1 Scopus citations
1 Scopus citations

Letter: metformin reduces the risk of hepatocellular carcinoma in diabetic patients. Authors' reply

Vilar-Gomez, E. & Chalasani, N., Oct 1 2019, In : Alimentary Pharmacology and Therapeutics. 50, 7, p. 838-839 2 p.

Research output: Contribution to journalLetter

7 Scopus citations
7 Scopus citations

Nonalcoholic Fatty Liver Disease and the Heart: JACC State-of-the-Art Review

Stahl, E. P., Dhindsa, D. S., Lee, S. K., Sandesara, P. B., Chalasani, N. P. & Sperling, L. S., Mar 5 2019, In : Journal of the American College of Cardiology. 73, 8, p. 948-963 16 p.

Research output: Contribution to journalReview article

18 Scopus citations

Novel HLA class I alleles outside the extended DR3 haplotype are protective against autoimmune hepatitis

Lammert, C., McKinnon, E. J., Chalasani, N. & Phillips, E. J., Jun 1 2019, In : Clinical and translational gastroenterology. 10, 6, e-00032.

Research output: Contribution to journalArticle

Open Access

Older Age and Disease Duration Are Highly Associated with Hepatocellular Carcinoma in Patients with Autoimmune Hepatitis

Dakhoul, L., Jones, K. R., Gawrieh, S., Ghabril, M., McShane, C., Vuppalanchi, R., Vilar-Gomez, E., Nephew, L., Chalasani, N. & Lammert, C., Jun 15 2019, In : Digestive diseases and sciences. 64, 6, p. 1705-1710 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Oxidized Derivatives of Linoleic Acid in Pediatric Metabolic Syndrome: Is Their Pathogenic Role Modulated by the Genetic Background and the Gut Microbiota?

Tricò, D., Di Sessa, A., Caprio, S., Chalasani, N., Liu, W., Liang, T., Graf, J., Herzog, R. I., Johnson, C. D., Umano, G. R., Feldstein, A. E. & Santoro, N., Jan 10 2019, In : Antioxidants and Redox Signaling. 30, 2, p. 241-250 10 p.

Research output: Contribution to journalArticle

7 Scopus citations
4 Scopus citations

Post hoc analyses of surrogate markers of non-alcoholic fatty liver disease (NAFLD) and liver fibrosis in patients with type 2 diabetes in a digitally supported continuous care intervention: An open-label, non-randomised controlled study

Vilar-Gomez, E., Athinarayanan, S. J., Adams, R. N., Hallberg, S. J., Bhanpuri, N. H., McKenzie, A. L., Campbell, W. W., McCarter, J. P., Phinney, S. D., Volek, J. S. & Chalasani, N., Feb 1 2019, In : BMJ open. 9, 2, 023597.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Prioritization of Therapeutic Targets and Trial Design in Cirrhotic Portal Hypertension

Abraldes, J. G., Trebicka, J., Chalasani, N., D’Amico, G., Rockey, D. C., Shah, V. H., Bosch, J. & Garcia-Tsao, G., Mar 2019, In : Hepatology. 69, 3, p. 1287-1299 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Randomized Controlled Trial of a Leucine-Metformin-Sildenafil Combination (NS-0200) on Weight and Metabolic Parameters

Zemel, M. B., Kolterman, O., Rinella, M., Vuppalanchi, R., Flores, O., Barritt, A. S., Siddiqui, M. & Chalasani, N., Jan 1 2019, In : Obesity. 27, 1, p. 59-67 9 p.

Research output: Contribution to journalArticle

2 Scopus citations