A 10-year-old girl with coexistent moyamoya disease and Grave's disease

Meredith Golomb, Jose Biller, Jodi Smith, Mary Edwards-Brown, Juan Sanchez, Todd Nebesio, Bhuwan P. Garg

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

There are rare reports of young women with moyamoya disease associated with Graves' disease; we are unaware of any previous reports of this association in prepubescent girls. We report a 10-year-old girl who presented with multiple bilateral strokes. Cerebral angiography demonstrated moderate to severe stenosis of her bilateral distal internal carotid arteries and proximal anterior and middle cerebral arteries, which was greater on the right. Thyroid function tests demonstrated suppressed thyroid-stimulating hormone and elevated thyroid hormone levels. Serum antiphospholipid antibody screen demonstrated mild elevations of antiocardiolipin IgG. Possible mechanisms predisposing individuals to concurrent moyamoya and Graves' disease are discussed.

Original languageEnglish
Pages (from-to)620-624
Number of pages5
JournalJournal of Child Neurology
Volume20
Issue number7
StatePublished - Jul 2005

Fingerprint

Moyamoya Disease
Graves Disease
Anterior Cerebral Artery
Thyroid Function Tests
Cerebral Angiography
Antiphospholipid Antibodies
Middle Cerebral Artery
Internal Carotid Artery
Thyrotropin
Thyroid Hormones
Pathologic Constriction
Immunoglobulin G
Stroke
Serum

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health

Cite this

A 10-year-old girl with coexistent moyamoya disease and Grave's disease. / Golomb, Meredith; Biller, Jose; Smith, Jodi; Edwards-Brown, Mary; Sanchez, Juan; Nebesio, Todd; Garg, Bhuwan P.

In: Journal of Child Neurology, Vol. 20, No. 7, 07.2005, p. 620-624.

Research output: Contribution to journalArticle

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