A 41-year-old woman with von hippel-lindau and a cerebellar lesion

Sarah E. Martin, Sohaib M. Al-Khatib, Michael S. Turner, Annette C. Douglas-Akinwande, Eyas M. Hattab

Research output: Contribution to journalArticle

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Abstract

A 41-year-old woman with a 12-year history of von Hippel-Lindau disease presented with progressive quadriparesis and difficulty swallowing. MRI revealed a well-circumscribed, partially cystic cerebellar neoplasm, consistent with hemangioblastoma. The tumor was resected and the diagnosis of hemangioblastoma confirmed. Embedded within the hemangioblastoma was a small focus of metastatic renal cell carcinoma (RCC). RCC metastatic to a CNS hemangioblastoma is the second most common type of tumor-to-tumor metastasis, which may be due to a number of factors. Proper immunostaining panels are required to clearly identify these cases since both tumor may have similar histology.

Original languageEnglish
Pages (from-to)511-514
Number of pages4
JournalBrain Pathology
Volume20
Issue number2
DOIs
StatePublished - Mar 2010

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Hemangioblastoma
Renal Cell Carcinoma
Neoplasms
Cerebellar Neoplasms
von Hippel-Lindau Disease
Quadriplegia
Deglutition
Histology
Neoplasm Metastasis

ASJC Scopus subject areas

  • Neuroscience(all)
  • Pathology and Forensic Medicine
  • Clinical Neurology

Cite this

Martin, S. E., Al-Khatib, S. M., Turner, M. S., Douglas-Akinwande, A. C., & Hattab, E. M. (2010). A 41-year-old woman with von hippel-lindau and a cerebellar lesion. Brain Pathology, 20(2), 511-514. https://doi.org/10.1111/j.1750-3639.2009.00363.x

A 41-year-old woman with von hippel-lindau and a cerebellar lesion. / Martin, Sarah E.; Al-Khatib, Sohaib M.; Turner, Michael S.; Douglas-Akinwande, Annette C.; Hattab, Eyas M.

In: Brain Pathology, Vol. 20, No. 2, 03.2010, p. 511-514.

Research output: Contribution to journalArticle

Martin, SE, Al-Khatib, SM, Turner, MS, Douglas-Akinwande, AC & Hattab, EM 2010, 'A 41-year-old woman with von hippel-lindau and a cerebellar lesion', Brain Pathology, vol. 20, no. 2, pp. 511-514. https://doi.org/10.1111/j.1750-3639.2009.00363.x
Martin SE, Al-Khatib SM, Turner MS, Douglas-Akinwande AC, Hattab EM. A 41-year-old woman with von hippel-lindau and a cerebellar lesion. Brain Pathology. 2010 Mar;20(2):511-514. https://doi.org/10.1111/j.1750-3639.2009.00363.x
Martin, Sarah E. ; Al-Khatib, Sohaib M. ; Turner, Michael S. ; Douglas-Akinwande, Annette C. ; Hattab, Eyas M. / A 41-year-old woman with von hippel-lindau and a cerebellar lesion. In: Brain Pathology. 2010 ; Vol. 20, No. 2. pp. 511-514.
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