A 41-year-old woman with von hippel-lindau and a cerebellar lesion

Sarah E. Martin, Sohaib M. Al-Khatib, Michael S. Turner, Annette C. Douglas-Akinwande, Eyas M. Hattab

Research output: Contribution to journalArticle

5 Scopus citations


A 41-year-old woman with a 12-year history of von Hippel-Lindau disease presented with progressive quadriparesis and difficulty swallowing. MRI revealed a well-circumscribed, partially cystic cerebellar neoplasm, consistent with hemangioblastoma. The tumor was resected and the diagnosis of hemangioblastoma confirmed. Embedded within the hemangioblastoma was a small focus of metastatic renal cell carcinoma (RCC). RCC metastatic to a CNS hemangioblastoma is the second most common type of tumor-to-tumor metastasis, which may be due to a number of factors. Proper immunostaining panels are required to clearly identify these cases since both tumor may have similar histology.

Original languageEnglish (US)
Pages (from-to)511-514
Number of pages4
JournalBrain Pathology
Issue number2
StatePublished - Mar 1 2010

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Neuroscience(all)
  • Clinical Neurology

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    Martin, S. E., Al-Khatib, S. M., Turner, M. S., Douglas-Akinwande, A. C., & Hattab, E. M. (2010). A 41-year-old woman with von hippel-lindau and a cerebellar lesion. Brain Pathology, 20(2), 511-514. https://doi.org/10.1111/j.1750-3639.2009.00363.x