A 61-year-old woman with osteomalacia and a thoracic spine lesion

Ann E. Marshall, Sarah E. Martin, Narasimhan P. Agaram, Jey Hsin Chen, Eric M. Horn, Annette C. Douglas-Akinwande, Eyas M. Hattab

Research output: Contribution to journalArticle

9 Scopus citations


Phosphaturic mesenchymal tumor, mixed connective tissue variant (PMT-MCT) is a rare, largely benign, mesenchymal neoplasm almost invariably associated with oncogenic osteomalacia. It is generally found in the soft tissue and bone of the extremities. We report a case of a 61-year-old female with long-standing osteomalacia who was found to have PMT-MCT of the thoracic spine. There have been very few previously reported cases of PMT involving the spinal vertebrae and neuropathologists should be aware of this lesion. Recognition of PMT-MCT is critical for optimal patient care since complete surgical resection without additional therapy is curative.

Original languageEnglish (US)
Pages (from-to)499-502
Number of pages4
JournalBrain Pathology
Issue number2
StatePublished - Mar 1 2010

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Neuroscience(all)
  • Clinical Neurology

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    Marshall, A. E., Martin, S. E., Agaram, N. P., Chen, J. H., Horn, E. M., Douglas-Akinwande, A. C., & Hattab, E. M. (2010). A 61-year-old woman with osteomalacia and a thoracic spine lesion. Brain Pathology, 20(2), 499-502. https://doi.org/10.1111/j.1750-3639.2009.00360.x