A Balancing Act: PGRPs Preserve and Protect

Research output: Contribution to journalShort survey

5 Scopus citations

Abstract

How does the immune system maintain a balance between preserving a beneficial microbiome and protecting against pathogens while also inducing effective, yet not damaging, responses? In this issue of Cell Host & Microbe, Charroux et al. (2018) reveal that, in Drosophila, this task is performed by three isoforms of PGRP-LB, a peptidoglycan-hydrolyzing amidase. How does the immune system maintain a balance between preserving a beneficial microbiome and protecting against pathogens while also inducing effective, yet not damaging, responses? In this issue of Cell Host & Microbe, Charroux et al. (2018) reveal that, in Drosophila, this task is performed by three isoforms of PGRP-LB, a peptidoglycan-hydrolyzing amidase.

Original languageEnglish (US)
Pages (from-to)149-151
Number of pages3
JournalCell Host and Microbe
Volume23
Issue number2
DOIs
StatePublished - Feb 14 2018

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Virology

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