A brain magnetic resonance imaging study of pituitary gland morphology in anorexia nervosa and bulimia

P. Murali Doraiswamy, K. Ranga Rama Krishnan, Gary S. Figiel, Mustafa M. Husain, Orest B. Boyko, W. J. Kenneth Rockwell, Everett H. Ellinwood

Research output: Contribution to journalArticle

45 Scopus citations

Abstract

Magnetic resonance imaging (MRI) of the brain was used to examine the morphology and dimensions of the pituitary gland in 18 patients with eating disorders (8 anorectics and 10 bulimics), in comparison with 13 healthy volunteers. None of the 18 patients with anorexia or bulimia had any radiological evidence suggestive of pituitary macroadenoma. cyst, or empty sella. Measurements revealed that the anorectics and bulimics had smaller pituitary gland cross-sectional areas (p < 0.05) and smaller pituitary gland heights, compared with healthy controls. These preliminary findings in anorectics and bulimics are suggestive of pituitary atrophy secondary to nutritional or endocrine alterations, rather than a primary pituitary pathology.

Original languageEnglish (US)
Pages (from-to)110-116
Number of pages7
JournalBiological psychiatry
Volume28
Issue number2
DOIs
StatePublished - Jul 15 1990

ASJC Scopus subject areas

  • Biological Psychiatry

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    Murali Doraiswamy, P., Ranga Rama Krishnan, K., Figiel, G. S., Husain, M. M., Boyko, O. B., Kenneth Rockwell, W. J., & Ellinwood, E. H. (1990). A brain magnetic resonance imaging study of pituitary gland morphology in anorexia nervosa and bulimia. Biological psychiatry, 28(2), 110-116. https://doi.org/10.1016/0006-3223(90)90628-F