A case of high-risk penile epithelioid hemangioendothelioma

Alexei Wedmid, Timothy Masterson, Robert G. Maki, Paul Russo

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background. A 48-year-old, previously healthy man presented to his local urologist with several small, violaceous, indurated lesions along the shaft of his penis and glans, which caused discomfort and penile curvature. Four weeks previously, the lesions were three small painless blemishes. Peyronie disease was initially diagnosed, but the disease progressed despite steroid treatment. Following the results of a biopsy, multifocal angiosarcoma was diagnosed. CT of the chest, abdomen and pelvis was negative for metastatic disease. At this point the patient was referred to a specialist oncology center for further management. Investigations. At the specialty center, the patient underwent physical examination, additional excisional biopsies, and PET-CT. Diagnosis. Penile epithelioid hemangioendothelioma, which is a multifocal, atypical epithelioid vascular tumor. Management. Single-agent chemotherapy using liposomal doxorubicin hydrochloride for eight cycles, followed by 63 Gy of adjuvant external beam radiation therapy to the penis fractionated over 35 treatments.

Original languageEnglish (US)
Pages (from-to)223-227
Number of pages5
JournalNature Reviews Urology
Volume6
Issue number4
DOIs
StatePublished - Apr 2009
Externally publishedYes

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Epithelioid Hemangioendothelioma
Penis
Penile Induration
Biopsy
Hemangiosarcoma
Pelvis
Abdomen
Doxorubicin
Physical Examination
Blood Vessels
Radiotherapy
Thorax
Steroids
Drug Therapy
Therapeutics
Neoplasms

ASJC Scopus subject areas

  • Urology
  • Medicine(all)

Cite this

A case of high-risk penile epithelioid hemangioendothelioma. / Wedmid, Alexei; Masterson, Timothy; Maki, Robert G.; Russo, Paul.

In: Nature Reviews Urology, Vol. 6, No. 4, 04.2009, p. 223-227.

Research output: Contribution to journalArticle

Wedmid, Alexei ; Masterson, Timothy ; Maki, Robert G. ; Russo, Paul. / A case of high-risk penile epithelioid hemangioendothelioma. In: Nature Reviews Urology. 2009 ; Vol. 6, No. 4. pp. 223-227.
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