A cell-permeable synthetic transcription factor mimic

Xiangshu Xiao, Peng Yu, Hyun Suk Lim, Devanjan Sikder, Thomas Kodadek

Research output: Contribution to journalArticle

64 Scopus citations

Abstract

Do you copy? A cell-permeable synthetic transcription factor mimic composed of a DNA-binding hairpin polyamide and an activation-domain-like peptoid can turn on gene transcription in living cells. (Figure Presented).

Original languageEnglish (US)
Pages (from-to)2865-2868
Number of pages4
JournalAngewandte Chemie - International Edition
Volume46
Issue number16
DOIs
StatePublished - Jul 2 2007

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Keywords

  • DNA
  • DNA transcription
  • Ligands
  • Peptoids
  • Polyamides

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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