A clinical and histomorphometric study of calcium sulfate compared with freeze-dried bone allograft for alveolar ridge preservation

Samira M. Toloue, Ioana Chesnoiu-Matei, Steven B. Blanchard

Research output: Contribution to journalArticle

34 Scopus citations

Abstract

Background: Manymaterials have been found to be effective in ridge preservation. The purpose of this study is to determine whether calciumsulfate (CS) is as effective as freeze-dried bone allograft (FDBA) in preserving postextraction ridge dimensions and to evaluate the amount of new bone formation and graft clearance through histologic analysis. Methods: Thirty-one extraction sites were selected. Postextraction clinical measurements were made, and sites were divided randomly into the test group (CS) or the control group (FDBA). After graft placement, all individuals received the same postoperative treatment and instructions. Participants were recalled after 3 months, measurements were made, and sites were re-entered. Bone samples were harvested and analyzed with histologic methodology for new bone formation and remaining residual graft. Results: Thirteen test and 15 control sites were evaluated. There was no significant change in vertical ridge height before or after surgery within the test and control groups (P = 0.57, P = 0.68, respectively). Therewas a significant decrease in bucco-lingual ridge width for both groups (P = 0.0003, P = 0.0075, respectively), but the difference between groups was not significant (P = 0.11).Histologic analysis revealed an average of 32% newbone formation with 2.5%graft remaining for the test group and 16.7% new bone formation with 21%graft remaining for the control. Conclusions: Results indicate thatCS is as effective asFDBA in preserving postextraction ridge dimensions in non-molar extraction sites. There is greater clearance of CS with more new bone formation after ≈3months compared with FDBA in these sites.

Original languageEnglish (US)
Pages (from-to)847-855
Number of pages9
JournalJournal of periodontology
Volume83
Issue number7
DOIs
StatePublished - Jul 1 2012

Keywords

  • Alveolar ridge augmentation
  • Bone regeneration
  • Bone transplantation
  • Dental implant
  • Guided tissue regeneration

ASJC Scopus subject areas

  • Periodontics

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