A color Doppler analysis of nifedipine-induced posterior ocular blood flow changes in open-angle glaucoma

Richard P. Wilson, Warren J. Chang, Robert C. Sergott, Marlene R. Moster, Courtland M. Schmidt, J. Brent Bond, Alon Harris

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

Purpose: This pilot study used color Doppler imaging to investigate the effects of nifedipine on the posterior ocular blood flow of patients with glaucoma progression at normal intraocular pressures. Patients and Methods: Eighteen patients, 11 men and seven women with a median age of 61.7 years, were imaged before and 6 weeks after the initiation of 30 mg of sustained-release nifedipine (Procardia XL; produced by either Pfizer or Pratt) daily. Results: There was no statistically significant change in the blood velocity of the ophthalmic artery, central retinal artery, and main nasal and temporal short posterior ciliary arteries after treatment with nifedipine. Conclusion: The routine use of nifedipine in patients with normal tension glaucoma progression is not supported by this study.

Original languageEnglish (US)
Pages (from-to)231-236
Number of pages6
JournalJournal of Glaucoma
Volume6
Issue number4
StatePublished - Aug 1 1997

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Keywords

  • Color Doppler
  • Nifedipine
  • Normal tension glaucoma
  • Optic nerve blood

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Wilson, R. P., Chang, W. J., Sergott, R. C., Moster, M. R., Schmidt, C. M., Bond, J. B., & Harris, A. (1997). A color Doppler analysis of nifedipine-induced posterior ocular blood flow changes in open-angle glaucoma. Journal of Glaucoma, 6(4), 231-236.