A combined structural-functional classification of schizophrenia using hippocampal volume plus fMRI activation

James Ford, Li Shen, Fillia Makedon, Laura A. Flashman, Andrew Saykin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

9 Citations (Scopus)

Abstract

Previous work has demonstrated that fMRI activations in individual anatomic regions can be used as a basis for classifying subjects for schizophrenia. Here we demonstrate that this classification, which is approximately 75-83% accurate for the hippocampal formation, can be improved by incorporating hippocampal volume information, which alone classifies at chance levels of accuracy. The best combined classifier is about 87% accurate and uses only right hippocampal activation and volume data. These accuracy figures should be considered approximate due to the limited size of our test dataset (N=23, 15 patients and 8 controls).

Original languageEnglish (US)
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Pages48-49
Number of pages2
Volume1
StatePublished - 2002
Externally publishedYes
EventProceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) - Houston, TX, United States
Duration: Oct 23 2002Oct 26 2002

Other

OtherProceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS)
CountryUnited States
CityHouston, TX
Period10/23/0210/26/02

Fingerprint

Chemical activation
Classifiers
Magnetic Resonance Imaging

Keywords

  • Classification
  • FLD
  • Schizophrenia

ASJC Scopus subject areas

  • Bioengineering

Cite this

Ford, J., Shen, L., Makedon, F., Flashman, L. A., & Saykin, A. (2002). A combined structural-functional classification of schizophrenia using hippocampal volume plus fMRI activation. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (Vol. 1, pp. 48-49)

A combined structural-functional classification of schizophrenia using hippocampal volume plus fMRI activation. / Ford, James; Shen, Li; Makedon, Fillia; Flashman, Laura A.; Saykin, Andrew.

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 1 2002. p. 48-49.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Ford, J, Shen, L, Makedon, F, Flashman, LA & Saykin, A 2002, A combined structural-functional classification of schizophrenia using hippocampal volume plus fMRI activation. in Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. vol. 1, pp. 48-49, Proceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS), Houston, TX, United States, 10/23/02.
Ford J, Shen L, Makedon F, Flashman LA, Saykin A. A combined structural-functional classification of schizophrenia using hippocampal volume plus fMRI activation. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 1. 2002. p. 48-49
Ford, James ; Shen, Li ; Makedon, Fillia ; Flashman, Laura A. ; Saykin, Andrew. / A combined structural-functional classification of schizophrenia using hippocampal volume plus fMRI activation. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 1 2002. pp. 48-49
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