A Comparison of Data Driven-based Measures of Adherence to Oral Hypoglycemic Agents in Medicaid Patients

Vivienne J. Zhu, Wanzhu Tu, Marc Rosenman, J. Marc Overhage

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

We evaluated and compared different methods for measuring adherence to Oral Antihyperglycemic Agents (OHA), based on the correlation between these measures and glycated hemoglobin A1C (HbA1c) levels in Medicaid patients with Type 2 diabetes. An observational sample of 831 Medicaid patients with Type 2 diabetes who had HbA1c test results recorded between January 1, 2001 and December 31, 2005 was identified in the Indiana Network of Patient Care (INPC). OHA adherence was measured by medication possession ratio (MPR), proportion of days covered (PDC), and the number of gaps (GAP) for 3, 6, and 12-month intervals prior to the HbA1c test date. All three OHA adherence measurements showed consistent and significant correlation with HbA1c level. The 6-month PDC showed the strongest association with HbA1c levels in both unadjusted (-1.07, P

Original languageEnglish (US)
Pages (from-to)1294-1301
Number of pages8
JournalAMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium
Volume2014
StatePublished - 2014

Fingerprint

Medicaid
Hypoglycemic Agents
Hemoglobins
Type 2 Diabetes Mellitus
Glycosylated Hemoglobin A
Patient Care

ASJC Scopus subject areas

  • Medicine(all)

Cite this

@article{1efad563c799431ca85425e86cc2854d,
title = "A Comparison of Data Driven-based Measures of Adherence to Oral Hypoglycemic Agents in Medicaid Patients",
abstract = "We evaluated and compared different methods for measuring adherence to Oral Antihyperglycemic Agents (OHA), based on the correlation between these measures and glycated hemoglobin A1C (HbA1c) levels in Medicaid patients with Type 2 diabetes. An observational sample of 831 Medicaid patients with Type 2 diabetes who had HbA1c test results recorded between January 1, 2001 and December 31, 2005 was identified in the Indiana Network of Patient Care (INPC). OHA adherence was measured by medication possession ratio (MPR), proportion of days covered (PDC), and the number of gaps (GAP) for 3, 6, and 12-month intervals prior to the HbA1c test date. All three OHA adherence measurements showed consistent and significant correlation with HbA1c level. The 6-month PDC showed the strongest association with HbA1c levels in both unadjusted (-1.07, P",
author = "Zhu, {Vivienne J.} and Wanzhu Tu and Marc Rosenman and Overhage, {J. Marc}",
year = "2014",
language = "English (US)",
volume = "2014",
pages = "1294--1301",
journal = "AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium",
issn = "1559-4076",
publisher = "American Medical Informatics Association",

}

TY - JOUR

T1 - A Comparison of Data Driven-based Measures of Adherence to Oral Hypoglycemic Agents in Medicaid Patients

AU - Zhu, Vivienne J.

AU - Tu, Wanzhu

AU - Rosenman, Marc

AU - Overhage, J. Marc

PY - 2014

Y1 - 2014

N2 - We evaluated and compared different methods for measuring adherence to Oral Antihyperglycemic Agents (OHA), based on the correlation between these measures and glycated hemoglobin A1C (HbA1c) levels in Medicaid patients with Type 2 diabetes. An observational sample of 831 Medicaid patients with Type 2 diabetes who had HbA1c test results recorded between January 1, 2001 and December 31, 2005 was identified in the Indiana Network of Patient Care (INPC). OHA adherence was measured by medication possession ratio (MPR), proportion of days covered (PDC), and the number of gaps (GAP) for 3, 6, and 12-month intervals prior to the HbA1c test date. All three OHA adherence measurements showed consistent and significant correlation with HbA1c level. The 6-month PDC showed the strongest association with HbA1c levels in both unadjusted (-1.07, P

AB - We evaluated and compared different methods for measuring adherence to Oral Antihyperglycemic Agents (OHA), based on the correlation between these measures and glycated hemoglobin A1C (HbA1c) levels in Medicaid patients with Type 2 diabetes. An observational sample of 831 Medicaid patients with Type 2 diabetes who had HbA1c test results recorded between January 1, 2001 and December 31, 2005 was identified in the Indiana Network of Patient Care (INPC). OHA adherence was measured by medication possession ratio (MPR), proportion of days covered (PDC), and the number of gaps (GAP) for 3, 6, and 12-month intervals prior to the HbA1c test date. All three OHA adherence measurements showed consistent and significant correlation with HbA1c level. The 6-month PDC showed the strongest association with HbA1c levels in both unadjusted (-1.07, P

UR - http://www.scopus.com/inward/record.url?scp=84964313110&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84964313110&partnerID=8YFLogxK

M3 - Article

VL - 2014

SP - 1294

EP - 1301

JO - AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium

JF - AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium

SN - 1559-4076

ER -