A comparison of ibuprofen versus acetaminophen with codeine in the young tonsillectomy patient

C. S. St. Charles, Bruce Matt, M. M. Hamilton, Barry Katz

Research output: Contribution to journalArticle

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Abstract

OBJECTIVE: To compare the use of ibuprofen with the use of acetaminophen with codeine for posttonsillectomy management. BACKGROUND: We were not satisfied with our traditional pain-management practice for tonsillectomy patients. We hoped to find a new approach for improved patient comfort and avoid scheduled, abusable drugs such as codeine. DESIGN: Intervention, prospective, randomized control trial. Follow-up was 1 month. SETTING: University referral center; institutional pediatric practice, ambulatory. PATIENTS: 110 children undergoing tonsillectomy with or without other procedures. Consecutive patients were offered participation. Enrollees were randomly assigned to one of two classes and analyzed with the initial assignment. No patients withdrew for adverse effects, although 12 in group 2 used codeine and 5 of those used acetaminophen, whereas 2 in group 1 received ibuprofen. INTERVENTIONS: Patients received either acetaminophen with codeine (group 1) or ibuprofen (group 2) for pastoperative pain control. MAIN OUTCOME MEASURES: The main outcomes, determined before initiation of the study, were assessment of (1) postoperative bleeding, (2) pain, (3) efficacy of relief of pain by drug, (4) nausea, (5) emesis, (6) readmission to hospital, (7) overage temperature, and (8) highest temperature after surgery. RESULTS: The only statistically significant difference is less nausea in patients receiving ibuprofen (p = 0.0049). Of note, no difference existed in postoperative bleeding, pain, or temperature control. CONCLUSIONS: Ibuprofen is at least as effective as acetaminophen with codeine for postoperative pain control in children after tonsillectomy.

Original languageEnglish
Pages (from-to)76-82
Number of pages7
JournalOtolaryngology - Head and Neck Surgery
Volume117
Issue number1
DOIs
StatePublished - 1997

Fingerprint

Tonsillectomy
Ibuprofen
Codeine
Postoperative Pain
Pain
Nausea
Temperature
Institutional Practice
Hemorrhage
Patient Readmission
Pain Management
Acetaminophen
Pharmaceutical Preparations
Vomiting
Referral and Consultation
codeine drug combination acetaminophen
Pediatrics

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

A comparison of ibuprofen versus acetaminophen with codeine in the young tonsillectomy patient. / St. Charles, C. S.; Matt, Bruce; Hamilton, M. M.; Katz, Barry.

In: Otolaryngology - Head and Neck Surgery, Vol. 117, No. 1, 1997, p. 76-82.

Research output: Contribution to journalArticle

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