Abstract
Purpose: Open partial nephrectomy (OPN) and robotic partial nephrectomy (RPN) are widely utilized techniques for small renal masses. The lack of tactile feedback and limitations of laparoscopy may result in differences in the surgical specimen that may impact oncologic outcome. We present postoperative pathological outcomes data in a cohort of patients matched for nephrometry score, tumor size, gender and age. Materials and methods: We reviewed 81 patients who underwent partial nephrectomy between January 2003 and March 2010. Twenty-seven underwent RPN and 54 received OPN. Two OPN cases were matched for nephrometry score, tumor size, gender and age for each RPN. Postoperative pathological specimens were reviewed by a urologic pathologist regarding margin status, pathologic stage, histology, renal capsule violation, among other variables. Results: Sixty-two (76.5 %) patients were found to have renal cell carcinoma on final pathology. Frozen sectioning with tumor bed sampling was intra-operatively employed in 70 cases (86.4 %). The overall positive margin occurrence was 1 of 81 patients, which occurred during an RPN for a hilar tumor and converted to radical nephrectomy to achieve negative clinical margins. Additionally, 14.8 % of OPN patients had renal capsule violation as compared to 3.7 % of RPN cases (p = 0.34). Importantly, the mean distance to the proximal margin edge for RPN specimens (2.77 mm) was equivalent to OPN (3.01 mm), p = 0.46. Conclusion: When matched for nephrometry score, tumor size, gender and age, RPN produces similar pathological outcomes to OPN.
| Original language | English |
|---|---|
| Pages (from-to) | 381-385 |
| Number of pages | 5 |
| Journal | International Urology and Nephrology |
| Volume | 45 |
| Issue number | 2 |
| DOIs | |
| State | Published - Apr 2013 |
Fingerprint
Keywords
- Margin
- Partial nephrectomy
- Pathology
ASJC Scopus subject areas
- Nephrology
- Urology
Cite this
A comparison of pathologic outcomes of matched robotic and open partial nephrectomies. / Mellon, Matthew J.; Lucas, Steven M.; Kum, Jennifer B J; Cheng, Liang; Sundaram, Chandru.
In: International Urology and Nephrology, Vol. 45, No. 2, 04.2013, p. 381-385.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A comparison of pathologic outcomes of matched robotic and open partial nephrectomies
AU - Mellon, Matthew J.
AU - Lucas, Steven M.
AU - Kum, Jennifer B J
AU - Cheng, Liang
AU - Sundaram, Chandru
PY - 2013/4
Y1 - 2013/4
N2 - Purpose: Open partial nephrectomy (OPN) and robotic partial nephrectomy (RPN) are widely utilized techniques for small renal masses. The lack of tactile feedback and limitations of laparoscopy may result in differences in the surgical specimen that may impact oncologic outcome. We present postoperative pathological outcomes data in a cohort of patients matched for nephrometry score, tumor size, gender and age. Materials and methods: We reviewed 81 patients who underwent partial nephrectomy between January 2003 and March 2010. Twenty-seven underwent RPN and 54 received OPN. Two OPN cases were matched for nephrometry score, tumor size, gender and age for each RPN. Postoperative pathological specimens were reviewed by a urologic pathologist regarding margin status, pathologic stage, histology, renal capsule violation, among other variables. Results: Sixty-two (76.5 %) patients were found to have renal cell carcinoma on final pathology. Frozen sectioning with tumor bed sampling was intra-operatively employed in 70 cases (86.4 %). The overall positive margin occurrence was 1 of 81 patients, which occurred during an RPN for a hilar tumor and converted to radical nephrectomy to achieve negative clinical margins. Additionally, 14.8 % of OPN patients had renal capsule violation as compared to 3.7 % of RPN cases (p = 0.34). Importantly, the mean distance to the proximal margin edge for RPN specimens (2.77 mm) was equivalent to OPN (3.01 mm), p = 0.46. Conclusion: When matched for nephrometry score, tumor size, gender and age, RPN produces similar pathological outcomes to OPN.
AB - Purpose: Open partial nephrectomy (OPN) and robotic partial nephrectomy (RPN) are widely utilized techniques for small renal masses. The lack of tactile feedback and limitations of laparoscopy may result in differences in the surgical specimen that may impact oncologic outcome. We present postoperative pathological outcomes data in a cohort of patients matched for nephrometry score, tumor size, gender and age. Materials and methods: We reviewed 81 patients who underwent partial nephrectomy between January 2003 and March 2010. Twenty-seven underwent RPN and 54 received OPN. Two OPN cases were matched for nephrometry score, tumor size, gender and age for each RPN. Postoperative pathological specimens were reviewed by a urologic pathologist regarding margin status, pathologic stage, histology, renal capsule violation, among other variables. Results: Sixty-two (76.5 %) patients were found to have renal cell carcinoma on final pathology. Frozen sectioning with tumor bed sampling was intra-operatively employed in 70 cases (86.4 %). The overall positive margin occurrence was 1 of 81 patients, which occurred during an RPN for a hilar tumor and converted to radical nephrectomy to achieve negative clinical margins. Additionally, 14.8 % of OPN patients had renal capsule violation as compared to 3.7 % of RPN cases (p = 0.34). Importantly, the mean distance to the proximal margin edge for RPN specimens (2.77 mm) was equivalent to OPN (3.01 mm), p = 0.46. Conclusion: When matched for nephrometry score, tumor size, gender and age, RPN produces similar pathological outcomes to OPN.
KW - Margin
KW - Partial nephrectomy
KW - Pathology
UR - http://www.scopus.com/inward/record.url?scp=84880727514&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84880727514&partnerID=8YFLogxK
U2 - 10.1007/s11255-013-0392-4
DO - 10.1007/s11255-013-0392-4
M3 - Article
C2 - 23386247
AN - SCOPUS:84880727514
VL - 45
SP - 381
EP - 385
JO - International Urology and Nephrology
JF - International Urology and Nephrology
SN - 0301-1623
IS - 2
ER -