A comparison of Terahertz Pulsed Imaging with transverse microradiography and microhardness to measure mineral changes in enamel after treatment with fluoride dentifrices

David Churchley, Frank Lippert, Richard Lynch, Jesse Alton, C. Gonzalez-Cabezas, J. Eder

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The aim of this study was to determine the ability of Terahertz Pulsed Imaging (TPI) to measure mineral changes in enamel lesions during de/remineralisation studies. A comparison was made between transverse microradiography (TMR) and microhardness measurements. Artificial lesions were formed in bovine enamel using a solution of 0.1 M lactic acid (pH 5.0) containing 0.2% Carbopol C907 and 50% saturated with hydroxyapatite. The 20 day experimental protocol consisted of four, one-minute treatment periods with dentifrices containing 10, 675, 1385 and 2700ppm fluoride, a 4 h/day acid challenge, and for the remaining time specimens were stored in a 50:50 pooled human / artificial saliva mixture. Terahertz images were generated by positioning the specimens at the focus of the beam and raster scanning the optics to collect the reflections from the air / enamel (AEI) and lesion / enamel (LEI) interface. Significant differences were observed in the intensity change from baseline of the AEI and LEI reflections upon treatment with the four dentifrices. A linear correlation was observed between δAEI vs δVHN (r 2 = 0.997), ΔAEI vs ΔKHN (r 2 =0.964), ΔII (ratio of LEI to AEI) vs ΔΔZ (r 2 =0.875) and ΔLEI vs ΔΔZ (r 2 =0.870). Statistically significant correlations (p

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7162
DOIs
StatePublished - 2009
Externally publishedYes
EventLasers in Dentistry XV - San Jose, CA, United States
Duration: Jan 24 2009Jan 24 2009

Other

OtherLasers in Dentistry XV
CountryUnited States
CitySan Jose, CA
Period1/24/091/24/09

Fingerprint

Terahertz Imaging
Microradiography
Dentifrices
enamels
Enamels
Dental Enamel
Fluorides
Microhardness
microhardness
Minerals
fluorides
lesions
minerals
Imaging techniques
Artificial Saliva
raster scanning
saliva
lactic acid
Durapatite
Lactic acid

Keywords

  • Caries
  • Microhardness
  • Microradiography
  • Remineralization
  • Terahertz imaging

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Churchley, D., Lippert, F., Lynch, R., Alton, J., Gonzalez-Cabezas, C., & Eder, J. (2009). A comparison of Terahertz Pulsed Imaging with transverse microradiography and microhardness to measure mineral changes in enamel after treatment with fluoride dentifrices. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 7162). [716203] https://doi.org/10.1117/12.816860

A comparison of Terahertz Pulsed Imaging with transverse microradiography and microhardness to measure mineral changes in enamel after treatment with fluoride dentifrices. / Churchley, David; Lippert, Frank; Lynch, Richard; Alton, Jesse; Gonzalez-Cabezas, C.; Eder, J.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7162 2009. 716203.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Churchley, D, Lippert, F, Lynch, R, Alton, J, Gonzalez-Cabezas, C & Eder, J 2009, A comparison of Terahertz Pulsed Imaging with transverse microradiography and microhardness to measure mineral changes in enamel after treatment with fluoride dentifrices. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 7162, 716203, Lasers in Dentistry XV, San Jose, CA, United States, 1/24/09. https://doi.org/10.1117/12.816860
Churchley D, Lippert F, Lynch R, Alton J, Gonzalez-Cabezas C, Eder J. A comparison of Terahertz Pulsed Imaging with transverse microradiography and microhardness to measure mineral changes in enamel after treatment with fluoride dentifrices. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7162. 2009. 716203 https://doi.org/10.1117/12.816860
Churchley, David ; Lippert, Frank ; Lynch, Richard ; Alton, Jesse ; Gonzalez-Cabezas, C. ; Eder, J. / A comparison of Terahertz Pulsed Imaging with transverse microradiography and microhardness to measure mineral changes in enamel after treatment with fluoride dentifrices. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7162 2009.
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abstract = "The aim of this study was to determine the ability of Terahertz Pulsed Imaging (TPI) to measure mineral changes in enamel lesions during de/remineralisation studies. A comparison was made between transverse microradiography (TMR) and microhardness measurements. Artificial lesions were formed in bovine enamel using a solution of 0.1 M lactic acid (pH 5.0) containing 0.2{\%} Carbopol C907 and 50{\%} saturated with hydroxyapatite. The 20 day experimental protocol consisted of four, one-minute treatment periods with dentifrices containing 10, 675, 1385 and 2700ppm fluoride, a 4 h/day acid challenge, and for the remaining time specimens were stored in a 50:50 pooled human / artificial saliva mixture. Terahertz images were generated by positioning the specimens at the focus of the beam and raster scanning the optics to collect the reflections from the air / enamel (AEI) and lesion / enamel (LEI) interface. Significant differences were observed in the intensity change from baseline of the AEI and LEI reflections upon treatment with the four dentifrices. A linear correlation was observed between δAEI vs δVHN (r 2 = 0.997), ΔAEI vs ΔKHN (r 2 =0.964), ΔII (ratio of LEI to AEI) vs ΔΔZ (r 2 =0.875) and ΔLEI vs ΔΔZ (r 2 =0.870). Statistically significant correlations (p",
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