A comparison of young women's actual and assigned timing of use of a microbicide surrogate

Amanda E. Tanner, Katherine A. Roof, Barry Katz, Adrian Katschke, J. Fortenberry, Gregory Zimet

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Purpose: This study examined young women's actual timing of use of a microbicide surrogate gel (vaginal moisturiser (VM)) compared with assigned timing conditions. Methods: Participants used a VM with coitus during 4-week cycles over a 3-year period in random timing sequences: 1h before coitus, 10min before coitus and 10min after coitus. Daily diaries collected information related to coital behaviours, VM use and timing, and participants' and partners' VM assessments. Descriptive and mixed-effects model analyses were conducted. Results: At least three VM timing conditions were completed by 109 women aged 18-22 years old. Of 17 772 diary days collected, coitus was reported on 2128 (1252 with VM use; 59%). Median times between VM application and coitus were: 60min before coitus (mean=68.2; s.d.=76.9) for the 1-h pre-coital group, 13.5min before coitus (mean=44.9; s.d.=117.1) for the 10-min pre-coital group and 5min before coitus (mean=24.5; s.d.=205.1) for the 10-min post-coital group. Women reported that the VM was very easy to use (68%), it was somewhat messy (61%), they were very wet during sex (81%), sex was very good (80%) and their partners liked using the VM (38%). Conclusions: Overall, the VM was rated positively. There was substantial deviation in application time across timing conditions, with significantly greater variability in the post-coital group. These findings contribute to understanding of how VMs are accepted and used, with implications for HIV prevention with microbicides requiring specific application timing.

Original languageEnglish
Pages (from-to)299-303
Number of pages5
JournalSexual Health
Volume9
Issue number4
DOIs
StatePublished - 2012

Fingerprint

Coitus
Anti-Infective Agents
Foams and Jellies Vaginal Creams
HIV

Keywords

  • acceptability
  • application
  • HIV prevention
  • STI prevention
  • vaginal microbicide

ASJC Scopus subject areas

  • Infectious Diseases
  • Public Health, Environmental and Occupational Health

Cite this

A comparison of young women's actual and assigned timing of use of a microbicide surrogate. / Tanner, Amanda E.; Roof, Katherine A.; Katz, Barry; Katschke, Adrian; Fortenberry, J.; Zimet, Gregory.

In: Sexual Health, Vol. 9, No. 4, 2012, p. 299-303.

Research output: Contribution to journalArticle

Tanner, Amanda E. ; Roof, Katherine A. ; Katz, Barry ; Katschke, Adrian ; Fortenberry, J. ; Zimet, Gregory. / A comparison of young women's actual and assigned timing of use of a microbicide surrogate. In: Sexual Health. 2012 ; Vol. 9, No. 4. pp. 299-303.
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abstract = "Purpose: This study examined young women's actual timing of use of a microbicide surrogate gel (vaginal moisturiser (VM)) compared with assigned timing conditions. Methods: Participants used a VM with coitus during 4-week cycles over a 3-year period in random timing sequences: 1h before coitus, 10min before coitus and 10min after coitus. Daily diaries collected information related to coital behaviours, VM use and timing, and participants' and partners' VM assessments. Descriptive and mixed-effects model analyses were conducted. Results: At least three VM timing conditions were completed by 109 women aged 18-22 years old. Of 17 772 diary days collected, coitus was reported on 2128 (1252 with VM use; 59{\%}). Median times between VM application and coitus were: 60min before coitus (mean=68.2; s.d.=76.9) for the 1-h pre-coital group, 13.5min before coitus (mean=44.9; s.d.=117.1) for the 10-min pre-coital group and 5min before coitus (mean=24.5; s.d.=205.1) for the 10-min post-coital group. Women reported that the VM was very easy to use (68{\%}), it was somewhat messy (61{\%}), they were very wet during sex (81{\%}), sex was very good (80{\%}) and their partners liked using the VM (38{\%}). Conclusions: Overall, the VM was rated positively. There was substantial deviation in application time across timing conditions, with significantly greater variability in the post-coital group. These findings contribute to understanding of how VMs are accepted and used, with implications for HIV prevention with microbicides requiring specific application timing.",
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