A “Connexin” Responsible for the Fatal Attraction of Cancer to Bone

David L. Waning, Theresa Guise, Khalid Mohammad

Research output: Contribution to journalArticle

Abstract

Tumor cell interactions with the bone microenvironment are vital for the establishment and progression of bone metastases. Recently in Cancer Cell, Wang et al. (2018) showed that cells of the osteoblast lineage are critical for the delivery of calcium to tumor cells through gap junctions, pointing toward potential therapies for bone metastases.

Original languageEnglish (US)
JournalCell Metabolism
DOIs
StateAccepted/In press - Jan 1 2018

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Bone Neoplasms
Connexins
Bone and Bones
Neoplasm Metastasis
Neoplasms
Gap Junctions
Cell Lineage
Osteoblasts
Cell Communication
Calcium
Therapeutics

ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Cell Biology

Cite this

A “Connexin” Responsible for the Fatal Attraction of Cancer to Bone. / Waning, David L.; Guise, Theresa; Mohammad, Khalid.

In: Cell Metabolism, 01.01.2018.

Research output: Contribution to journalArticle

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