A magnetic resonance image study of age-related changes in human putamen nuclei

William M. McDonald, Mustafa Husain, P. Murali Doraiswamy, Gary Figiel, Orest Boyko, Ranga Rama Krishnan

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

Putamen nuclei were assessed in 36 normal volunteers using magnetic resonance imaging and a systematic sampling method. There was a significant decrease in the volume of the putamen nuclei with advancing age (r = —0.74, p < 0.0001), and an associated decline in the volume of the caudate nuclei (r = 0.60, p < 0.0001). The implications of these findings in age-associated motor abnormalities are discussed.

Original languageEnglish (US)
Pages (from-to)57-60
Number of pages4
JournalNeuroReport
Volume2
Issue number1
StatePublished - 1991
Externally publishedYes

Fingerprint

Putamen
Magnetic Resonance Spectroscopy
Caudate Nucleus
Healthy Volunteers
Magnetic Resonance Imaging

Keywords

  • Age-related changes
  • Magnetic resonance image
  • Putamen nuclei
  • Stereology

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

McDonald, W. M., Husain, M., Doraiswamy, P. M., Figiel, G., Boyko, O., & Krishnan, R. R. (1991). A magnetic resonance image study of age-related changes in human putamen nuclei. NeuroReport, 2(1), 57-60.

A magnetic resonance image study of age-related changes in human putamen nuclei. / McDonald, William M.; Husain, Mustafa; Doraiswamy, P. Murali; Figiel, Gary; Boyko, Orest; Krishnan, Ranga Rama.

In: NeuroReport, Vol. 2, No. 1, 1991, p. 57-60.

Research output: Contribution to journalArticle

McDonald, WM, Husain, M, Doraiswamy, PM, Figiel, G, Boyko, O & Krishnan, RR 1991, 'A magnetic resonance image study of age-related changes in human putamen nuclei', NeuroReport, vol. 2, no. 1, pp. 57-60.
McDonald WM, Husain M, Doraiswamy PM, Figiel G, Boyko O, Krishnan RR. A magnetic resonance image study of age-related changes in human putamen nuclei. NeuroReport. 1991;2(1):57-60.
McDonald, William M. ; Husain, Mustafa ; Doraiswamy, P. Murali ; Figiel, Gary ; Boyko, Orest ; Krishnan, Ranga Rama. / A magnetic resonance image study of age-related changes in human putamen nuclei. In: NeuroReport. 1991 ; Vol. 2, No. 1. pp. 57-60.
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