A new C-nucleoside analogue of tiazofurin: Synthesis and biological evaluation of 2-β-D-ribofuranosylimidazole-4-carboxamide (imidazofurin)

Palmarisa Franchetti, Stefano Marchetti, Loredana Cappellacci, Joel A. Yalowitz, Hiremagalur N. Jayaram, Barry M. Goldstein, Mario Grifantini

Research output: Contribution to journalArticle

34 Scopus citations

Abstract

2-β-D-Ribofuranosylimidazole-4-carboxamide, an imidazole analogue of the antitumor agent tiazofurin, was synthesized and evaluated for the growth inhibitory activity of human myelogenous leukemia K562 cells. (C) 2000 Elsevier Science Ltd.

Original languageEnglish (US)
Pages (from-to)67-69
Number of pages3
JournalBioorganic and Medicinal Chemistry Letters
Volume11
Issue number1
DOIs
StatePublished - Jan 8 2001

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ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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