A new overgrowth syndrome with accelerated skeletal maturation, unusual facies, and camptodactyly

David Weaver, C. Benjamin Graham, I. T. Thomas, David W. Smith

Research output: Contribution to journalArticle

99 Citations (Scopus)

Abstract

Two strikingly similar unrelated male children have the following pattern of anomalies: accelerated growth and osseous maturation, unusual craniofacial appearance, hoarse and low-pitched cry, and hypertonia with camptodactyly. The craniofacial abnormalities include large ears, broad forehead with hypertelorism, and long philtrum in relation to the relatively small mouth and mandible. The excessive growth is of prenatal onset and has continued at two to three times the normal rate with dysharmonic acceleration of skeletal maturation.

Original languageEnglish (US)
Pages (from-to)547-552
Number of pages6
JournalJournal of Pediatrics
Volume84
Issue number4
DOIs
StatePublished - 1974
Externally publishedYes

Fingerprint

Craniofacial Abnormalities
Hypertelorism
Forehead
Growth
Lip
Mandible
Ear
Mouth

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

A new overgrowth syndrome with accelerated skeletal maturation, unusual facies, and camptodactyly. / Weaver, David; Graham, C. Benjamin; Thomas, I. T.; Smith, David W.

In: Journal of Pediatrics, Vol. 84, No. 4, 1974, p. 547-552.

Research output: Contribution to journalArticle

Weaver, David ; Graham, C. Benjamin ; Thomas, I. T. ; Smith, David W. / A new overgrowth syndrome with accelerated skeletal maturation, unusual facies, and camptodactyly. In: Journal of Pediatrics. 1974 ; Vol. 84, No. 4. pp. 547-552.
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