A novel antibacterial resin composite for improved dental restoratives

Yiming Weng, Leah Howard, Xia Guo, Voon Joe Chong, Richard L. Gregory, Dong Xie

Research output: Contribution to journalArticle

57 Scopus citations


A novel furanone-containing antibacterial resin composite has been prepared and evaluated. compressive strength (CS) and Streptococcus mutans viability were used to evaluate the mechanical strength and antibacterial activity of the composites. The modified resin composites showed a significant antibacterial activity without substantially decreasing the mechanical strengths. With 5-30 % addition of the furanone derivative, the composite kept its original CS unchanged but showed a significant antibacterial activity with a 16-68 % reduction in the S. mutans viability. Further, the antibacterial function of the new composite was not affected by human saliva. The aging study indicates that the composite may have a longlasting antibacterial function. Within the limitations of this study, it appears that the experimental antibacterial resin composite may potentially be developed into a clinically attractive dental restorative due to its high mechanical strength and antibacterial function.

Original languageEnglish (US)
Pages (from-to)1553-1561
Number of pages9
JournalJournal of Materials Science: Materials in Medicine
Issue number6
StatePublished - Jun 1 2012

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

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