A practical clinical approach to paediatric phosphate disorders

Erik Imel, Thomas O. Carpenter

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations

Abstract

Phosphate metabolism is critical to multiple systems andcellular functions. Disruption of any point in the pathwaysof phosphate metabolism may cause serum phosphate abnormalities and resultant acute or chronic clinicalconditions. The study of phosphate disorders hasrevealed a wealth of information regarding normal phosphatephysiology. Careful evaluation of affected patientsbased on pathophysiologic assessments will usuallyidentify the aetiology of hypophosphataemia or hyperphosphataemia,therapy. Because of the relative importance of chronic hypophosphataemia and hyperphosphataemia to bonedisease, much of this chapter will focus on chronic disorders,especially those mediated by excess or deficient fibroblastgrowth factor 23 functioning.

Original languageEnglish (US)
Title of host publicationCalcium and Bone Disorders in Children and Adolescents: Second Edition
PublisherS. Karger AG
Pages134-161
Number of pages28
Volume28
ISBN (Print)9783318054675, 9783318054668
DOIs
StatePublished - Jun 11 2015

ASJC Scopus subject areas

  • Medicine(all)

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    Imel, E., & Carpenter, T. O. (2015). A practical clinical approach to paediatric phosphate disorders. In Calcium and Bone Disorders in Children and Adolescents: Second Edition (Vol. 28, pp. 134-161). S. Karger AG. https://doi.org/10.1159/000381036