A practical diastereoselective synthesis of β-amino-α-hydroxy carboxylates

Jae Mok Lee, Hyun Suk Lim, Kyung Chang Seo, Sung Kee Chung

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Practical synthetic routes to β-amino-α-hydroxy carboxylates (AHC) have been developed from amino acids. Reduction of β-amino-α- keto esters 6 with NaBH4 was found to give anti-AHCs 7 in high de, which were efficiently converted to the corresponding syn-AHCs 8 via oxazolidine ring 10 formation.

Original languageEnglish (US)
Pages (from-to)3639-3641
Number of pages3
JournalTetrahedron Asymmetry
Issue number23
StatePublished - Nov 28 2003
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

Fingerprint Dive into the research topics of 'A practical diastereoselective synthesis of β-amino-α-hydroxy carboxylates'. Together they form a unique fingerprint.

Cite this