The construction and performance of a remote system is described for the synthesis of 62Cu-labeled pyruvaldehyde bis(N4-methylthiosemicarbazonato)copper(II), [62Cu]Cu(PTSM), a positron-emitting radiopharmaceutical for perfusion imaging. The remote system allows the shielded synthesis and purification of tracer using the 2 M HCl eluate of high-level (10-18 GBq)62Zn/62Cu radionuclide generator system. The remote system allows the [62Cu]Cu(PTSM) synthesis to be performed in under 8 min with ca 40% E.O.S. radiochemical yield and >98% radiochemical purity.
|Original language||English (US)|
|Number of pages||4|
|Journal||International Journal of Radiation Applications and Instrumentation. Part|
|State||Published - 1991|
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