A risk factor strategy for investigating affective illness.

John Nurnberger, D. C. Jimerson, W. E. Bunney

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A "risk factor" approach to affective illness is outlined. Characteristics which are correlated with vulnerability to depression (or mania) should be sought and attempts made to either modify them or elucidate a pathophysiologic link between the characteristic and the illness. Genetic factors, biochemical factors, life events, demographic variables, and behavioral factors may be examined under the assumption that affective illness is multifactorially determined. Identification of these risk factors by a prospective epidemiologic study in a geographically delimited area is discussed; the risk factor model is compared with the high-risk model.

Original languageEnglish
Pages (from-to)903-909
Number of pages7
JournalBiological Psychiatry
Volume18
Issue number8
StatePublished - Aug 1983
Externally publishedYes

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Bipolar Disorder
Epidemiologic Studies
Molecular Biology
Demography
Prospective Studies
Depression

ASJC Scopus subject areas

  • Biological Psychiatry

Cite this

A risk factor strategy for investigating affective illness. / Nurnberger, John; Jimerson, D. C.; Bunney, W. E.

In: Biological Psychiatry, Vol. 18, No. 8, 08.1983, p. 903-909.

Research output: Contribution to journalArticle

Nurnberger, J, Jimerson, DC & Bunney, WE 1983, 'A risk factor strategy for investigating affective illness.', Biological Psychiatry, vol. 18, no. 8, pp. 903-909.
Nurnberger, John ; Jimerson, D. C. ; Bunney, W. E. / A risk factor strategy for investigating affective illness. In: Biological Psychiatry. 1983 ; Vol. 18, No. 8. pp. 903-909.
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