A supervised method for calculation of perfusion/diffusion mismatch volume in acute stroke

Judy Rose James, Olaniyi Osuntokun, Karmen Yoder, Askiel Bruno, Evan D. Morris

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Abstract

We present our initial experience with a supervised technique for calculating the mismatch between lesion volumes on Perfusion and Diffusion weighted images of acute stroke. Our method was designed to be reliable and easy to use. It requires the intervention of a trained user at two points during the segmentation process: first to identify normal and lesion tissue, and second, to match a filter to artifact size. The time to analyze a single patient is 15 minutes or less. Statistical test showed us effect of rater or day. This performance suggests that personnel at multiple sites could use this method in future studies to evaluate the meaning and utility of the mismatch volume. Most of the variability in our measurements appears to be due to variability in the perfusion (MTT) images. We expect that this variability would be minimized with higher doses of contrast agent.

Original languageEnglish (US)
Title of host publication2004 2nd IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationMacro to Nano
Pages1295-1298
Number of pages4
StatePublished - Dec 1 2004
Event2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano - Arlington, VA, United States
Duration: Apr 15 2004Apr 18 2004

Publication series

Name2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
Volume2

Other

Other2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
CountryUnited States
CityArlington, VA
Period4/15/044/18/04

ASJC Scopus subject areas

  • Engineering(all)

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  • Cite this

    James, J. R., Osuntokun, O., Yoder, K., Bruno, A., & Morris, E. D. (2004). A supervised method for calculation of perfusion/diffusion mismatch volume in acute stroke. In 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano (pp. 1295-1298). (2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano; Vol. 2).