Abandonment of childhood cancer treatment in Western Kenya

Festus Njuguna, S. Mostert, A. Slot, S. Langat, J. Skiles, M. N. Sitaresmi, P. M. Van De Ven, J. Musimbi, H. Muliro, Rachel Vreeman, Gjl Kaspers

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Background: The most important reason for childhood cancer treatment failure in low-income countries is treatment abandonment. Objective: The aim of this study was to explore reasons for childhood cancer treatment abandonment and assess the clinical condition of these children. Design: This was a descriptive study using semistructured questionnaires. Home visits were conducted to interview families of childhood cancer patients, diagnosed between January 2007 and January 2009, who had abandoned treatment at the Moi Teaching and Referral Hospital (MTRH). Results: Between January 2007 and January 2009, 222 children were newly diagnosed with a malignancy at MTRH. Treatment outcome was documented in 180 patients. Of these 180 patients, 98 (54%) children abandoned treatment. From December 2011 until August 2012, 53 (54%) of the 98 families were contacted. Due to lack of contact information, 45 families were untraceable. From 53 contacted families, 46 (87%) families agreed to be interviewed. Reasons for abandonment were reported by 26 families, and they were diverse. Most common reasons were financial diffi culties (46%), inadequate access to health insurance (27%) and transportation dif ficulties (23%). Most patients (72%) abandoned treatment after the first 3 months had been completed. Of the 46 children who abandoned treatment, 9 (20%) were still alive: 6 (67%) of these children looked healthy and 3 (33%) ill. The remaining 37 (80%) children had passed away. Conclusions: Prevention of childhood cancer treatment abandonment requires improved access to health insurance, financial or transportation support, proper parental education, psychosocial guidance and ameliorated communication skills of healthcare providers.

Original languageEnglish
Pages (from-to)609-614
Number of pages6
JournalArchives of Disease in Childhood
Issue number7
StatePublished - 2014

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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    Njuguna, F., Mostert, S., Slot, A., Langat, S., Skiles, J., Sitaresmi, M. N., Van De Ven, P. M., Musimbi, J., Muliro, H., Vreeman, R., & Kaspers, G. (2014). Abandonment of childhood cancer treatment in Western Kenya. Archives of Disease in Childhood, 99(7), 609-614. https://doi.org/10.1136/archdischild-2013-305257