Abdominal radical trachelectomy: A fertility-preserving option for women with early cervical cancer

László Ungár, László Pálfalvi, Russell Hogg, Pál Siklós, Deborah C M Boyle, Giuseppe Del Priore, Richard R. Smith

Research output: Contribution to journalArticle

160 Citations (Scopus)

Abstract

Abdominal radical trachelectomy is a fertility-preserving alternative to radical hysterectomy or chemoradiation for young women with stage IA2 to IB cervical cancers. Thirty-three patients were offered this procedure. The mean age was 30.5 years (range 23-37). Three procedures were abandoned because of positive pelvic nodes (two patients) and involvement of the margin between the amputated cervix and uterine fundus (one patient). Of the remaining 30 patients, 10 had stage IA2 tumours, 15 had stage IB1 and 5 had stage IB2. During follow up of a median of 47 months (mean 32 months, range 14-75 months), no recurrences have been detected. A normal menstrual pattern resumed within eight weeks of surgery in all but two patients. Five patients attempted to conceive. Three women have fallen pregnant, resulting in one first trimester miscarriage and two caesarean section deliveries at term. Our experience suggests that abdominal radical trachelectomy provides a method of treating women with stage IA2 to IB cervical cancers with conservation of fertility without apparently compromising recurrence or survival rates. It appears to provide equivalent oncological safety to a standard Wertheim hysterectomy using a technique familiar to all practising gynaecologic oncologists.

Original languageEnglish (US)
Pages (from-to)366-369
Number of pages4
JournalBJOG: An International Journal of Obstetrics and Gynaecology
Volume112
Issue number3
DOIs
StatePublished - Mar 2005
Externally publishedYes

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Uterine Cervical Neoplasms
Fertility
Hysterectomy
Patient Participation
Recurrence
Spontaneous Abortion
First Pregnancy Trimester
Cervix Uteri
Cesarean Section
Survival Rate
Trachelectomy
Safety
Neoplasms

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Abdominal radical trachelectomy : A fertility-preserving option for women with early cervical cancer. / Ungár, László; Pálfalvi, László; Hogg, Russell; Siklós, Pál; Boyle, Deborah C M; Del Priore, Giuseppe; Smith, Richard R.

In: BJOG: An International Journal of Obstetrics and Gynaecology, Vol. 112, No. 3, 03.2005, p. 366-369.

Research output: Contribution to journalArticle

Ungár, László ; Pálfalvi, László ; Hogg, Russell ; Siklós, Pál ; Boyle, Deborah C M ; Del Priore, Giuseppe ; Smith, Richard R. / Abdominal radical trachelectomy : A fertility-preserving option for women with early cervical cancer. In: BJOG: An International Journal of Obstetrics and Gynaecology. 2005 ; Vol. 112, No. 3. pp. 366-369.
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