Absence of long term pulmonary sequelae after mild meconium aspiration syndrome.

John Stevens, H. Eigen, D. Wysomierski

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

To assess residual damage from meconium aspiration syndrome (MAS), we studied 12 children, ages 6 to 9 years, an average of 7.4 years after injury. Our sample consisted of mildly affected patients, only one having required intubation and mechanical ventilation in the acute phase of illness. In each child we measured FVC, FEV1, PEFR, MMEFR, VisoV, lung volumes by plethysmography, DLCO and calculated FEV1/FVC and RV/TLC. Methacholine bronchial challenge was performed and the PD20 was calculated. These results were compared with those obtained from a group of 12 normal children studied in our laboratory. No significant difference was found for pulmonary function parameters studied, except for VisoV which was greater in MAS patients than normals (P less than 0.02). Given the inherent high degree of variability with VisoV, we were not able to ascribe this isolated finding to be indicative of small airway disease in these asymptomatic patients. We conclude that patients with mild to moderate initial insult from MAS show an absence of pulmonary sequelae when tested at an average of 7.4 years of age.

Original languageEnglish
Pages (from-to)74-81
Number of pages8
JournalPediatric Pulmonology
Volume5
Issue number2
StatePublished - 1988

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Meconium Aspiration Syndrome
Lung
Peak Expiratory Flow Rate
Asymptomatic Diseases
Plethysmography
Methacholine Chloride
Artificial Respiration
Intubation
Wounds and Injuries

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine

Cite this

Absence of long term pulmonary sequelae after mild meconium aspiration syndrome. / Stevens, John; Eigen, H.; Wysomierski, D.

In: Pediatric Pulmonology, Vol. 5, No. 2, 1988, p. 74-81.

Research output: Contribution to journalArticle

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