Acupuncture for the Treatment of Adults with Posttraumatic Stress Disorder: A Systematic Review and Meta-Analysis

Sean Grant, Benjamin Colaiaco, Aneesa Motala, Roberta Shanman, Melony Sorbero, Susanne Hempel

Research output: Contribution to journalReview article

Abstract

Acupuncture has been suggested as a treatment for posttraumatic stress disorder (PTSD), yet its clinical effects are unclear. This review aims to estimate effects of acupuncture on PTSD symptoms, depressive symptoms, anxiety symptoms, and sleep quality for adults with PTSD. We searched 10 databases in January 2016 to identify eligible randomized controlled trials (RCTs). We performed random effects meta-analyses and examined quality of the body of evidence (QoE) using the GRADE approach to rate confidence in meta-analytic effect estimates. Seven RCTs with 709 participants met inclusion criteria. We identified very low QoE indicating significant differences favoring acupuncture (versus any comparator) at post-intervention on PTSD symptoms (standardized mean difference [SMD] = −0.80, 95% confidence interval [CI] [−1.59, −0.01], 6 RCTs), and low QoE at longer follow-up on PTSD (SMD = −0.46, 95% CI [−0.85, −0.06], 4 RCTs) and depressive symptoms (SMD = −0.56; 95% CI [−0.88, −0.23], 4 RCTs). No significant differences were observed between acupuncture and comparators at post-intervention for depressive symptoms (SMD = −0.58, 95% CI [−1.18, 0.01], 6 RCTs, very low QoE), anxiety symptoms (SMD = −0.82, 95% CI [−2.16, 0.53], 4 RCTs, very low QoE), and sleep quality (SMD = −0.46, 95% CI [−3.95, 3.03], 2 RCTs, low QoE). Safety data (7 RCTs) suggest little risk of serious adverse events, though some participants experienced minor/moderate pain, superficial bleeding, and hematoma at needle insertion sites. To increase confidence in findings, sufficiently powered replication trials are needed that measure all relevant clinical outcomes and dedicate study resources to minimizing participant attrition.

Original languageEnglish (US)
Pages (from-to)39-58
Number of pages20
JournalJournal of Trauma and Dissociation
Volume19
Issue number1
DOIs
StatePublished - Jan 1 2018
Externally publishedYes

Fingerprint

Acupuncture Therapy
Post-Traumatic Stress Disorders
Meta-Analysis
Randomized Controlled Trials
Acupuncture
Confidence Intervals
Depression
Sleep
Anxiety
Hematoma
Needles
Outcome Assessment (Health Care)
Databases
Hemorrhage
Safety
Pain

Keywords

  • Alternative medicine
  • complementary medicine
  • meta-analysis
  • posttraumatic stress disorder
  • systematic review

ASJC Scopus subject areas

  • Clinical Psychology
  • Psychiatry and Mental health

Cite this

Acupuncture for the Treatment of Adults with Posttraumatic Stress Disorder : A Systematic Review and Meta-Analysis. / Grant, Sean; Colaiaco, Benjamin; Motala, Aneesa; Shanman, Roberta; Sorbero, Melony; Hempel, Susanne.

In: Journal of Trauma and Dissociation, Vol. 19, No. 1, 01.01.2018, p. 39-58.

Research output: Contribution to journalReview article

Grant, Sean ; Colaiaco, Benjamin ; Motala, Aneesa ; Shanman, Roberta ; Sorbero, Melony ; Hempel, Susanne. / Acupuncture for the Treatment of Adults with Posttraumatic Stress Disorder : A Systematic Review and Meta-Analysis. In: Journal of Trauma and Dissociation. 2018 ; Vol. 19, No. 1. pp. 39-58.
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