Acute bacterial meningitis

Research output: Contribution to journalReview article

32 Scopus citations


In the past 10 years the epidemiology of bacterial meningitis has changed, with a decreased incidence of meningitis caused by Haemophilus influenzae and an increasing incidence of meningitis caused by penicillin- and cephalosporin-resistant strains of Streptococcus pneumoniae. Meningococcal meningitis has become an increasing threat to college students. Successful outcome from meningitis requires not only eradication of the bacterial pathogen but also management of the neurological complications of raised intracranial pressure, stroke, and seizure activity. In this article, the pathophysiology, etiology, clinical presentation, differential diagnosis, and management of acute bacterial meningitis are reviewed. The present recommendations for the use of dexamethasone in the treatment of this infection, the use of chemoprophylaxis, and the indications for vaccinations are included.

Original languageEnglish (US)
Pages (from-to)293-306
Number of pages14
JournalSeminars in neurology
Issue number3
StatePublished - Jan 1 2000


  • Bacterial meningitis
  • Dexamethasone
  • Vaccination

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

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