Acute myeloid leukemia diagnosis in the 21st century

Bryan L. Betz, Jay L. Hess

Research output: Contribution to journalArticle

34 Scopus citations

Abstract

Context.-Rapid advances in understanding the molecular biology of acute myeloid leukemia are transforming the approach to diagnosis, prognostication, and treatment of these cases. Objective.-To briefly review the current state of AML classification with a particular emphasis on the role of molecular studies and their impact on the management of acute myeloid leukemia and other malignancies. Data Sources.-Current literature and experience of the authors. Conclusions.-While morphology, immunophenotyping, cytogenetics, and clinical history continue to play an important role, an increasing number of molecular tests are now required to properly classify these cases.

Original languageEnglish (US)
Pages (from-to)1427-1433
Number of pages7
JournalArchives of Pathology and Laboratory Medicine
Volume134
Issue number10
StatePublished - Oct 1 2010
Externally publishedYes

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

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