Context.-Rapid advances in understanding the molecular biology of acute myeloid leukemia are transforming the approach to diagnosis, prognostication, and treatment of these cases. Objective.-To briefly review the current state of AML classification with a particular emphasis on the role of molecular studies and their impact on the management of acute myeloid leukemia and other malignancies. Data Sources.-Current literature and experience of the authors. Conclusions.-While morphology, immunophenotyping, cytogenetics, and clinical history continue to play an important role, an increasing number of molecular tests are now required to properly classify these cases.
|Original language||English (US)|
|Number of pages||7|
|Journal||Archives of Pathology and Laboratory Medicine|
|State||Published - Oct 1 2010|
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Medical Laboratory Technology