Adverse effects of nonsteroidal anti-inflammatory drugs on renal function

M. D. Murray, D. C. Brater

Research output: Contribution to journalEditorial

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Renal deterioration from nonsteroidal anti-inflammatory drugs (NSAIDs) occurs in patients with prostaglandin-dependent renal function. Whelton and colleagues in this issue show that all NSAIDs are capable of producing these effects in patients at risk. Epidemiologic studies have not supported a conclusion that any problem exists. Many of these studies, however, either lacked sensitivity or excluded patients with risk factors. Results from both interventional and better epidemiologic studies are needed to make decisions about the status of NSAIDs.

Original languageEnglish (US)
Pages (from-to)I-3+559-560
JournalAnnals of internal medicine
Issue number8
StatePublished - Jan 1 1990


ASJC Scopus subject areas

  • Internal Medicine

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