African Descent and Glaucoma Evaluation Study (ADAGES): II. Ancestry differences in optic disc, retinal nerve fiber layer, and macular structure in healthy subjects

Christopher A. Girkin, Pamela A. Sample, Jeffrey M. Liebmann, Sonia Jain, Christopher Bowd, Lida M. Becerra, Felipe A. Medeiros, Lyne Racette, Keri A. Dirkes, Robert N. Weinreb, Linda M. Zangwill

Research output: Contribution to journalArticle

65 Citations (Scopus)

Abstract

Objective: To define differences in optic disc, retinal nerve fiber layer, and macular structure between healthy participants of African (AD) and European descent (ED) using quantitative imaging techniques in the African Descent and Glaucoma Evaluation Study (ADAGES). Methods: Reliable images were obtained using stereoscopic photography, confocal scanning laser ophthalmoscopy (Heidelberg retina tomography [HRT]), and optical coherence tomography (OCT) for 648 healthy subjects in ADAGES. Findings were compared and adjusted for age, optic disc area, and reference plane height where appropriate. Results: The AD participants had significantly greater optic disc area on HRT (2.06 mm2; P2; P

Original languageEnglish (US)
Pages (from-to)541-550
Number of pages10
JournalArchives of Ophthalmology
Volume128
Issue number5
DOIs
StatePublished - May 2010
Externally publishedYes

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Optic Disk
Nerve Fibers
Glaucoma
Healthy Volunteers
Retina
Tomography
Ophthalmoscopy
Photography
Optical Coherence Tomography
Lasers

ASJC Scopus subject areas

  • Ophthalmology

Cite this

African Descent and Glaucoma Evaluation Study (ADAGES) : II. Ancestry differences in optic disc, retinal nerve fiber layer, and macular structure in healthy subjects. / Girkin, Christopher A.; Sample, Pamela A.; Liebmann, Jeffrey M.; Jain, Sonia; Bowd, Christopher; Becerra, Lida M.; Medeiros, Felipe A.; Racette, Lyne; Dirkes, Keri A.; Weinreb, Robert N.; Zangwill, Linda M.

In: Archives of Ophthalmology, Vol. 128, No. 5, 05.2010, p. 541-550.

Research output: Contribution to journalArticle

Girkin, CA, Sample, PA, Liebmann, JM, Jain, S, Bowd, C, Becerra, LM, Medeiros, FA, Racette, L, Dirkes, KA, Weinreb, RN & Zangwill, LM 2010, 'African Descent and Glaucoma Evaluation Study (ADAGES): II. Ancestry differences in optic disc, retinal nerve fiber layer, and macular structure in healthy subjects', Archives of Ophthalmology, vol. 128, no. 5, pp. 541-550. https://doi.org/10.1001/archophthalmol.2010.49
Girkin, Christopher A. ; Sample, Pamela A. ; Liebmann, Jeffrey M. ; Jain, Sonia ; Bowd, Christopher ; Becerra, Lida M. ; Medeiros, Felipe A. ; Racette, Lyne ; Dirkes, Keri A. ; Weinreb, Robert N. ; Zangwill, Linda M. / African Descent and Glaucoma Evaluation Study (ADAGES) : II. Ancestry differences in optic disc, retinal nerve fiber layer, and macular structure in healthy subjects. In: Archives of Ophthalmology. 2010 ; Vol. 128, No. 5. pp. 541-550.
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