Age and sex-dependent trends in pulmonary embolism testing and derivation of a clinical decision rule for young patients

John Mongan, Jeffrey Kline, Rebecca Smith-Bindman

Research output: Contribution to journalArticle

9 Scopus citations


Importance Despite low prevalence of pulmonary embolism (PE) in young adults, they are frequently imaged for PE, which involves radiation exposure and substantial financial cost. Objective: Determine the use and positive proportions for PE imaging by age, differences in clinical presentation of PE by age and the projected impact of an age-targeted decision rule. Design: Analysis of two national population-based datasets: the 2009 Nationwide Emergency Department Sample, a 20% sample of US emergency departments (EDs) and the 2003-2006 Pulmonary Embolism Rule-out Criteria (PERC) dataset, a multisite cohort of ED patients with suspected PE from 12 US EDs. Results: Prevalence of PE was 10 times lower in young patients (18-35 years) than in older patients (>65 years) (0.06% vs 0.60%, p

Original languageEnglish (US)
Pages (from-to)840-845
Number of pages6
JournalEmergency Medicine Journal
Issue number11
StatePublished - Nov 1 2015


ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine
  • Emergency Medicine

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