Age at injury is associated with the long-term cognitive outcome of traumatic brain injuries

Alzheimer's Disease Neuroimaging Initiative

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Introduction The association between age at injury (AAI) and long-term cognitive outcome of traumatic brain injuries (TBI) is debatable. Methods Eligible participants with a history of TBI from Alzheimer's Disease Neuroimaging Initiative were divided into a childhood TBI (cTBI) group (the AAI ≤ 21 years old) and an adult TBI (aTBI) group (the AAI > 21 years old). Results The cTBI group has a higher Everyday Cognition total score than the aTBI group. All perceived cognitive functions are worse for the cTBI group than for the aTBI group except memory. By contrast, the cTBI group has higher assessment scores on either the Boston Naming Test or Rey Auditory Verbal Learning Test than the aTBI group. Discussion The AAI is associated with the long-term cognitive outcomes in older adults with a history of TBI.

Original languageEnglish (US)
Pages (from-to)196-200
Number of pages5
JournalAlzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring
Volume6
DOIs
StatePublished - 2017

Fingerprint

Wounds and Injuries
Cognition
Verbal Learning
Neuroimaging
Alzheimer Disease
Age Groups
Traumatic Brain Injury

Keywords

  • Alzheimer's disease
  • Dementia
  • Executive function
  • TBI

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health

Cite this

Age at injury is associated with the long-term cognitive outcome of traumatic brain injuries. / Alzheimer's Disease Neuroimaging Initiative.

In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, Vol. 6, 2017, p. 196-200.

Research output: Contribution to journalArticle

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N2 - Introduction The association between age at injury (AAI) and long-term cognitive outcome of traumatic brain injuries (TBI) is debatable. Methods Eligible participants with a history of TBI from Alzheimer's Disease Neuroimaging Initiative were divided into a childhood TBI (cTBI) group (the AAI ≤ 21 years old) and an adult TBI (aTBI) group (the AAI > 21 years old). Results The cTBI group has a higher Everyday Cognition total score than the aTBI group. All perceived cognitive functions are worse for the cTBI group than for the aTBI group except memory. By contrast, the cTBI group has higher assessment scores on either the Boston Naming Test or Rey Auditory Verbal Learning Test than the aTBI group. Discussion The AAI is associated with the long-term cognitive outcomes in older adults with a history of TBI.

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