Agreement between clinical screening procedures for neuropathy in the feet

​Yi  ​Wang, Jaclyn M. Goodrich, Robert Werner, Brenda Gillespie, Niladri Basu, Alfred Franzblau

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Introduction: The correlation between monofilament testing, symptom surveys, and electrodiagnostic studies for the diagnosis of axonal polyneuropathy has not been well studied. This investigation was done to assess the agreement between these procedures in a non-random sample of volunteers. Methods: The procedures evaluated included electrodiagnostic tests of the sural nerve, monofilament testing of the great toe, a symptom survey, and a body diagram. Kappa coefficients and sensitivity and specificity, using nerve conduction as a "gold standard," were used to determine the agreement between various combinations of procedures. Results: Poor agreement (kappa values -0.12-0.44) and sensitivity (sensitivity <30%) were found for all combinations of symptoms and monofilament results in comparison with sural peak latency and amplitude. Conclusions: Overall, the results demonstrated a low discriminatory power for the screening procedures for identifying persons with impaired sural nerve function. The results highlight the need for further development and evaluation of screening methods for distal neuropathy in population-based studies.

Original languageEnglish (US)
Pages (from-to)653-658
Number of pages6
JournalMuscle and Nerve
Volume45
Issue number5
DOIs
StatePublished - May 1 2012
Externally publishedYes

Fingerprint

Foot
Sural Nerve
Hallux
Polyneuropathies
Neural Conduction
Volunteers
Sensitivity and Specificity
Population
Surveys and Questionnaires

Keywords

  • Agreement
  • Monofilament
  • Nerve conduction
  • Sural nerve, symptom

ASJC Scopus subject areas

  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Physiology (medical)
  • Physiology

Cite this

​Wang, Y., Goodrich, J. M., Werner, R., Gillespie, B., Basu, N., & Franzblau, A. (2012). Agreement between clinical screening procedures for neuropathy in the feet. Muscle and Nerve, 45(5), 653-658. https://doi.org/10.1002/mus.23238

Agreement between clinical screening procedures for neuropathy in the feet. / ​Wang, ​Yi ; Goodrich, Jaclyn M.; Werner, Robert; Gillespie, Brenda; Basu, Niladri; Franzblau, Alfred.

In: Muscle and Nerve, Vol. 45, No. 5, 01.05.2012, p. 653-658.

Research output: Contribution to journalArticle

​Wang, Y, Goodrich, JM, Werner, R, Gillespie, B, Basu, N & Franzblau, A 2012, 'Agreement between clinical screening procedures for neuropathy in the feet', Muscle and Nerve, vol. 45, no. 5, pp. 653-658. https://doi.org/10.1002/mus.23238
​Wang Y, Goodrich JM, Werner R, Gillespie B, Basu N, Franzblau A. Agreement between clinical screening procedures for neuropathy in the feet. Muscle and Nerve. 2012 May 1;45(5):653-658. https://doi.org/10.1002/mus.23238
​Wang, ​Yi  ; Goodrich, Jaclyn M. ; Werner, Robert ; Gillespie, Brenda ; Basu, Niladri ; Franzblau, Alfred. / Agreement between clinical screening procedures for neuropathy in the feet. In: Muscle and Nerve. 2012 ; Vol. 45, No. 5. pp. 653-658.
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