Allergic eosinophilic esophagitis is an increasingly recognized disease in various parts of the world. The clinical presentation mimics other gastrointestinal diseases, especially gastroesophageal reflux disease, making endoscopic examination and histological evaluation of esophageal mucosal biopsies crucial to accurate diagnosis. The pathogenesis likely involves allergen-initiated, TH2-dependent, IL-5 mediated infiltration of eosinophilis into the esophageal mucosa. Therapies currently favored include dietary modifications and use of corticosteroids.
|Original language||English (US)|
|Number of pages||7|
|Journal||Indian journal of pediatrics|
|State||Published - Oct 2006|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health