Alterations in epithelial polarity and the pathogenesis of disease states

Eileen M. Fish, Bruce Molitoris

Research output: Contribution to journalArticle

179 Citations (Scopus)

Abstract

The establishment and maintenance of epithelial-cell polarity are prerequisites for normal epithelial-cell and organ function. Knowledge of the processes involved in cell polarity has provided insight into the mechanisms of cell dysfunction and the pathogenesis of several diseases. These insights should lead to the development of specific strategies aimed at preventing or minimizing the progression of these diseases.

Original languageEnglish
Pages (from-to)1580-1588
Number of pages9
JournalNew England Journal of Medicine
Volume330
Issue number22
DOIs
StatePublished - 1994

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Cell Polarity
Epithelial Cells
Disease Progression
Maintenance

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Alterations in epithelial polarity and the pathogenesis of disease states. / Fish, Eileen M.; Molitoris, Bruce.

In: New England Journal of Medicine, Vol. 330, No. 22, 1994, p. 1580-1588.

Research output: Contribution to journalArticle

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