Amphibians as research models for regenerative medicine

Fengyu Song, Bingbing Li, David L. Stocum

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

The ability to regenerate bone across a critical size defect would be a marked clinical advance over current methods for dealing with such structural gaps. Here, we briefly review the development of limb bones and the mandible, the regeneration of urodele limbs after amputation, and present evidence that urodele and anuran amphibians represent a valuable research model for the study of segment defect regeneration in both limb bones and mandible.

Original languageEnglish (US)
Pages (from-to)141-150
Number of pages10
JournalOrganogenesis
Volume6
Issue number3
DOIs
StatePublished - Jul 2010
Externally publishedYes

Fingerprint

Regenerative Medicine
Amphibians
Bone
Extremities
Mandible
Research
Bone and Bones
Defects
Bone Regeneration
Amputation
Regeneration

Keywords

  • Critical size defect
  • Endochondral bone
  • Frog
  • Growth factors
  • Intramembranous bone
  • Limb regeneration
  • Salamander
  • Scaffolds

ASJC Scopus subject areas

  • Developmental Biology
  • Embryology
  • Transplantation
  • Biomedical Engineering

Cite this

Amphibians as research models for regenerative medicine. / Song, Fengyu; Li, Bingbing; Stocum, David L.

In: Organogenesis, Vol. 6, No. 3, 07.2010, p. 141-150.

Research output: Contribution to journalArticle

Song, Fengyu ; Li, Bingbing ; Stocum, David L. / Amphibians as research models for regenerative medicine. In: Organogenesis. 2010 ; Vol. 6, No. 3. pp. 141-150.
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