An Empirical Validation of Recursive Noisy OR (RNOR) Rule for Asthma Prediction

Vibha Anand, Stephen M. Downs

Research output: Contribution to journalArticle

2 Scopus citations


In 2004, an extension of the Noisy-OR formalism termed the Recursive Noisy-OR (RNOR) rule was published for estimating complex probabilistic interactions in a Bayesian Network (BN). The RNOR rule presents an algorithm to construct a complete conditional probability distribution (CPD) of a node while allowing domain causal relationships over and above causal independence to be tractably captured in a semantically meaningful way. However, to the best of our knowledge, the accuracy of this rule has not been tested empirically. In this paper, we report the results of a study that compares the performance of a data-trained expert BN (empiric BN) with the reformulated BN, using the RNOR rule. The original empiric BN was trained with a large dataset from the Regenstrief Medical Record System (RMRS). Furthermore, we evaluate conditions in our dataset which render the RNOR rule inapplicable and discuss our use of Noisy-OR calculations in such situations. We call this approach "Adaptive Recursive Noisy-OR".

Original languageEnglish (US)
Pages (from-to)16-20
Number of pages5
JournalAMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium
StatePublished - Jan 1 2010


  • Adaptive Recursive Noisy OR
  • Asthma; Bayesian Network
  • Noisy-OR
  • Recursive Noisy OR rule (RNOR)

ASJC Scopus subject areas

  • Medicine(all)

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