An evaluation of type A and B alcoholics

M. A. Schuckit, J. E. Tipp, T. L. Smith, E. Shapiro, V. M. Hesselbrock, K. K. Bucholz, T. Reich, John Nurnberger

Research output: Contribution to journalArticle

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Abstract

Evaluations of 1539 alcohol-dependent subjects (including 512 women) were carried out in an attempt to replicate the Type A/B dichotomy suggested by Babor et al.. The subjects are participants in the Collaborative Study on the Genetics of Alcoholism (COGA), and each was evaluated using a face-to-face structured interview. Following the procedure of Babor et al., data were used to create 17 domains, and a k-means clustering method was invoked to generate a two-cluster solution. Thirty-one per cent of the males and 25% of the females fell into the Type B group, with overall R2 of 0.22 and 0.24 for males and females, respectively. The scores in each of the 17 domains and the analyses of the clinical characteristics for Type A and B subjects were, in general, consistent with the earlier onset and more severe course for Type B men and women. The ability of the domains to identify, subgroups of alcoholics remained robust even after the exclusion of alcohol dependent subjects with antisocial personality disorder (ASPD) and those with an onset of alcohol dependence before age 25 years. The present analyses suggest that five of the 17 domains might be especially useful in identifying Type A and B groups.

Original languageEnglish (US)
Pages (from-to)1189-1203
Number of pages15
JournalAddiction
Volume90
Issue number9
DOIs
StatePublished - 1995
Externally publishedYes

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Alcoholics
Alcoholism
Alcohols
Antisocial Personality Disorder
Aptitude
Cluster Analysis
Interviews

ASJC Scopus subject areas

  • Medicine (miscellaneous)

Cite this

Schuckit, M. A., Tipp, J. E., Smith, T. L., Shapiro, E., Hesselbrock, V. M., Bucholz, K. K., ... Nurnberger, J. (1995). An evaluation of type A and B alcoholics. Addiction, 90(9), 1189-1203. https://doi.org/10.1111/j.1360-0443.1995.tb01089.x

An evaluation of type A and B alcoholics. / Schuckit, M. A.; Tipp, J. E.; Smith, T. L.; Shapiro, E.; Hesselbrock, V. M.; Bucholz, K. K.; Reich, T.; Nurnberger, John.

In: Addiction, Vol. 90, No. 9, 1995, p. 1189-1203.

Research output: Contribution to journalArticle

Schuckit, MA, Tipp, JE, Smith, TL, Shapiro, E, Hesselbrock, VM, Bucholz, KK, Reich, T & Nurnberger, J 1995, 'An evaluation of type A and B alcoholics', Addiction, vol. 90, no. 9, pp. 1189-1203. https://doi.org/10.1111/j.1360-0443.1995.tb01089.x
Schuckit MA, Tipp JE, Smith TL, Shapiro E, Hesselbrock VM, Bucholz KK et al. An evaluation of type A and B alcoholics. Addiction. 1995;90(9):1189-1203. https://doi.org/10.1111/j.1360-0443.1995.tb01089.x
Schuckit, M. A. ; Tipp, J. E. ; Smith, T. L. ; Shapiro, E. ; Hesselbrock, V. M. ; Bucholz, K. K. ; Reich, T. ; Nurnberger, John. / An evaluation of type A and B alcoholics. In: Addiction. 1995 ; Vol. 90, No. 9. pp. 1189-1203.
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