An integrative model of the impairments in insight in schizophrenia: emerging research on causal factors and treatments

Jenifer Vohs, Sunita George, Bethany L. Leonhardt, Paul H. Lysaker

Research output: Contribution to journalReview article

21 Scopus citations


Introduction: Poor insight, or unawareness of some major aspect of mental illness, is a major barrier to wellness when it interferes with persons seeking out treatment or forming their own understanding of the challenges they face. One barrier to addressing impaired insight is the absence of a comprehensive model of how poor insight develops. Areas covered: To explore this issue we review how poor insight is the result of multiple phenomena which interfere with the construction of narrative accounts of psychiatric challenges, rather than a single social or biological cause. Expert commentary: We propose an integrative model of poor insight in schizophrenia which involves the interaction of symptoms, deficits in neurocognition, social cognition, metacognition, and stigma. Emerging treatments for poor insight including therapies which focus on the development of metacognition are discussed.

Original languageEnglish (US)
Pages (from-to)1193-1204
Number of pages12
JournalExpert Review of Neurotherapeutics
Issue number10
StatePublished - Oct 2 2016



  • insight
  • metacognition
  • neurocognition
  • Schizophrenia
  • social cognition
  • stigma
  • symptoms

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology
  • Pharmacology (medical)

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