An update on the treatment of precocious puberty in McCune-Albright syndrome and testotoxicosis

Nadine Haddad, Erica Eugster

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

McCune-Albright syndrome and testotoxicosis are rare forms of peripheral precocious puberty. Our understanding of the pathophysiology and mechanism of these diseases has significantly increased following identification of their underlying molecular etiology. However, their treatment remains challenging. We provide a review of the various treatment modalities used in both conditions with an update on recent trials using novel and promising pharmacological agents.

Original languageEnglish
Pages (from-to)653-661
Number of pages9
JournalJournal of Pediatric Endocrinology and Metabolism
Volume20
Issue number6
StatePublished - Jun 2007

Fingerprint

Polyostotic Fibrous Dysplasia
Precocious Puberty
Pharmacology
Sexual precocity

Keywords

  • Aromatase inhibitors
  • McCune-Albright syndrome
  • Testotoxicosis

ASJC Scopus subject areas

  • Endocrinology
  • Pediatrics, Perinatology, and Child Health

Cite this

An update on the treatment of precocious puberty in McCune-Albright syndrome and testotoxicosis. / Haddad, Nadine; Eugster, Erica.

In: Journal of Pediatric Endocrinology and Metabolism, Vol. 20, No. 6, 06.2007, p. 653-661.

Research output: Contribution to journalArticle

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